DE3261987D1 - 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same - Google Patents

4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same

Info

Publication number
DE3261987D1
DE3261987D1 DE8282300619T DE3261987T DE3261987D1 DE 3261987 D1 DE3261987 D1 DE 3261987D1 DE 8282300619 T DE8282300619 T DE 8282300619T DE 3261987 T DE3261987 T DE 3261987T DE 3261987 D1 DE3261987 D1 DE 3261987D1
Authority
DE
Germany
Prior art keywords
imidazolylmethyl
preparation
pharmaceutical composition
composition containing
cinnamic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282300619T
Other languages
English (en)
Inventor
Morita Kaname
Iizuka Kinji
Arikawa Shigeo
Akahane Kenji
Watanabe Mitsuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3261987D1 publication Critical patent/DE3261987D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8282300619T 1981-02-10 1982-02-09 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same Expired DE3261987D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56018488A JPS57131769A (en) 1981-02-10 1981-02-10 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, its preparation and drug containing the same

Publications (1)

Publication Number Publication Date
DE3261987D1 true DE3261987D1 (en) 1985-03-07

Family

ID=11973016

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282300619T Expired DE3261987D1 (en) 1981-02-10 1982-02-09 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same

Country Status (14)

Country Link
US (1) US4607046A (de)
EP (1) EP0058079B1 (de)
JP (1) JPS57131769A (de)
KR (1) KR880001865B1 (de)
AU (1) AU546907B2 (de)
CA (1) CA1173839A (de)
DE (1) DE3261987D1 (de)
DK (1) DK155736C (de)
ES (1) ES8302664A1 (de)
FI (1) FI77028C (de)
GR (1) GR75408B (de)
IE (1) IE52519B1 (de)
YU (1) YU42757B (de)
ZA (1) ZA82639B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855466A (ja) * 1981-09-28 1983-04-01 Kissei Pharmaceut Co Ltd 新規な1,3−二置換イミダゾ−ル誘導体及びその製造方法
TW208013B (de) * 1990-03-01 1993-06-21 Daiichi Co Ltd
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
CN114436964A (zh) * 2020-10-16 2022-05-06 赤峰经方医药技术开发有限责任公司 一种奥扎格雷的连续制备方法
CN115557898A (zh) * 2021-07-01 2023-01-03 诸葛国琴 一种咪唑类化合物、其中间体及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative

Also Published As

Publication number Publication date
US4607046A (en) 1986-08-19
DK54982A (da) 1982-08-11
ES509459A0 (es) 1983-01-16
AU8015482A (en) 1982-08-19
IE52519B1 (en) 1987-11-25
GR75408B (de) 1984-07-13
EP0058079A2 (de) 1982-08-18
JPH0234941B2 (de) 1990-08-07
DK155736B (da) 1989-05-08
KR830009043A (ko) 1983-12-17
ZA82639B (en) 1983-01-26
YU42757B (en) 1988-12-31
EP0058079A3 (en) 1982-09-08
EP0058079B1 (de) 1985-01-23
IE820289L (en) 1982-08-10
ES8302664A1 (es) 1983-01-16
FI77028B (fi) 1988-09-30
AU546907B2 (en) 1985-09-26
FI820379L (fi) 1982-08-11
KR880001865B1 (ko) 1988-09-23
DK155736C (da) 1989-09-25
CA1173839A (en) 1984-09-04
FI77028C (fi) 1989-01-10
YU27482A (en) 1985-03-20
JPS57131769A (en) 1982-08-14

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee