ES8301994A1 - Procedimiento para preparar derivados de tetrahidrotiopira- no-(3,2-b) indol - Google Patents

Procedimiento para preparar derivados de tetrahidrotiopira- no-(3,2-b) indol

Info

Publication number
ES8301994A1
ES8301994A1 ES502954A ES502954A ES8301994A1 ES 8301994 A1 ES8301994 A1 ES 8301994A1 ES 502954 A ES502954 A ES 502954A ES 502954 A ES502954 A ES 502954A ES 8301994 A1 ES8301994 A1 ES 8301994A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
tetrahydrothiopyrano
image
indole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502954A
Other languages
English (en)
Other versions
ES502954A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES502954A0 publication Critical patent/ES502954A0/es
Publication of ES8301994A1 publication Critical patent/ES8301994A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TETRAHIDROTIOPIRANO<014>3,2-B<015>INDOL Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R SON HIDROGENO O ALCOHILO C <003> ; R Y R PUEDEN SER VARIOS RADICALES; Y N VALE DE 0-2. CONSISTE EN INTRODUCIR UN SUSTITUYENTE R EN LA POSICION 5 DEL COMPUESTO DE FORMULA (I), EN LA QUE R ES HIDROGENO, POR TRATAMIENTO CON UN HALURO DEL SUSTITUYENTE R . LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE CONSTITUIDA POR UN COMPUESTO DE METAL ALCALINO, A TEMPERATURAS ENTRE LA AMBIENTE Y 100<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANALGESICA, ANTIINFLAMATORIA Y ANTIDEPRESORA.
ES502954A 1980-02-27 1981-06-11 Procedimiento para preparar derivados de tetrahidrotiopira- no-(3,2-b) indol Expired ES8301994A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2375180A JPS56120686A (en) 1980-02-27 1980-02-27 Tetrahydrothiopyrano 3,2-b indole derivative

Publications (2)

Publication Number Publication Date
ES502954A0 ES502954A0 (es) 1982-12-16
ES8301994A1 true ES8301994A1 (es) 1982-12-16

Family

ID=12119010

Family Applications (2)

Application Number Title Priority Date Filing Date
ES498968A Granted ES498968A0 (es) 1980-02-27 1981-01-30 Procedimiento para preparar derivados de tetrahidrotiopirano(3,2-b)indol
ES502954A Expired ES8301994A1 (es) 1980-02-27 1981-06-11 Procedimiento para preparar derivados de tetrahidrotiopira- no-(3,2-b) indol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES498968A Granted ES498968A0 (es) 1980-02-27 1981-01-30 Procedimiento para preparar derivados de tetrahidrotiopirano(3,2-b)indol

Country Status (8)

Country Link
US (1) US4910318A (es)
EP (1) EP0035259B1 (es)
JP (1) JPS56120686A (es)
AU (1) AU538185B2 (es)
CA (1) CA1158241A (es)
DE (1) DE3162851D1 (es)
DK (1) DK150305C (es)
ES (2) ES498968A0 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2639944B1 (fr) * 1988-12-06 1991-01-18 Adir Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2720064B1 (fr) * 1994-05-19 1996-06-28 Adir Thiacycloalkyl [b] indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
AU675141B2 (en) * 1993-07-20 1997-01-23 Adir Et Compagnie (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37060B1 (en) * 1972-01-13 1977-04-27 Ayerst Mckenna & Harrison Indole derivatives
JPS557201A (en) * 1978-05-23 1980-01-19 Shionogi & Co Ltd Derivative of tetrahydrothiopyrano(2,3-b)indole

Also Published As

Publication number Publication date
AU538185B2 (en) 1984-08-02
AU6793481A (en) 1981-09-03
EP0035259B1 (en) 1984-03-28
CA1158241A (en) 1983-12-06
ES502954A0 (es) 1982-12-16
DK85481A (da) 1981-08-28
JPS56120686A (en) 1981-09-22
US4910318A (en) 1990-03-20
EP0035259A1 (en) 1981-09-09
DK150305C (da) 1987-11-23
ES8201134A1 (es) 1981-12-01
ES498968A0 (es) 1981-12-01
DE3162851D1 (en) 1984-05-03
JPS6365675B2 (es) 1988-12-16
DK150305B (da) 1987-02-02

Similar Documents

Publication Publication Date Title
TW349946B (en) Novel naphthyl compounds and their process for preparation and pharmaceutical compositions containing same
ES8406080A1 (es) Un procedimiento para la preparacion de nuevos derivados de fosfolipidos.
HUT68029A (en) New 11-benzaldoxim-estradiene derivatives, pharmaceutical compositions containing them and process for producing them
DE3065304D1 (en) Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
ES8400422A1 (es) &#34;procedimiento de preparacion de eteres triciclicos, asi como de sus sales de adicion con un acido mineral u organico terapeuticamente compatible&#34;.
TW341565B (en) Indole derivatives processes and intermediates for their preparation and pharmaceutical compositions containing them
ES8503667A1 (es) Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
HUT68315A (en) New 11-benzaldoxime-17-beta-methoxy-17-alpha-methoxy-methyl-estradiene derivatives, pharmaceutical compositions containing them and process for producing them
ES8207155A1 (es) Un procedimiento para la preparacion de derivados de acido trans-(4-oxo-4h-quinazolin-3-il)-2-propenoico
ES479820A1 (es) Procedimiento para la preparacion de isoquinoleinas.
ES8501410A1 (es) Un procedimiento para la preparacion de nuevos derivados de fosfolipidos.
ZA815043B (en) Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof
ES473441A1 (es) Procedimiento para la preparacion de nuevos derivados de 5,-11-dihidro-6h-pirido (2,3-b)(1,4-benzodiazepin-6-ona).
ES8201134A1 (es) Procedimiento para preparar derivados de tetrahidrotiopirano(3,2-b)indol
ES8205770A1 (es) Procedimiento para la preparacion de derivados de 2,3-indo- lediona
ES480113A1 (es) Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina.
ES8800952A1 (es) Un procedimiento para la preparacion de derivados de carbapenem.
ES474367A1 (es) Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol.
ES8106129A1 (es) Un procedimiento para la preparacion de derivados de ciclo- hexadieno
AU4583489A (en) New indole derivatives, process for preparing them and pharmaceutical compositions containing them
HUT40637A (en) Process for preparing derivatives of dibenzo/be/oxepinyl-aeacetic acid derivatives and pharmaceutical compositions containing such compounds
ES8406457A1 (es) Procedimiento de preparacion de derivados de piperacina
ES8604122A1 (es) Procedimiento de preparacion de eteres oximas basicos y de sus sales de adicion acidas farmaceuticamente aceptables
ES8600203A1 (es) Procedimiento de preparacion de nuevos derivados aminoetoxibencilalcoholicos y de sus sales de adicion acidas y amonicas cuaternarias
ATE29133T1 (de) Troponon-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.