ES8301974A3 - A procedure for the preparation of a 4-fluorofenil-piperidine replaced in position 3 (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of a 4-fluorofenil-piperidine replaced in position 3 (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8301974A3 ES8301974A3 ES504997A ES504997A ES8301974A3 ES 8301974 A3 ES8301974 A3 ES 8301974A3 ES 504997 A ES504997 A ES 504997A ES 504997 A ES504997 A ES 504997A ES 8301974 A3 ES8301974 A3 ES 8301974A3
- Authority
- ES
- Spain
- Prior art keywords
- translation
- machine
- legally binding
- google translate
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Process for the obtaining of substitute 4-fluorophenil-piperidins in position 3 and of their physiologically compatible acid addition salts, of formula (I), where r is hydrogen or alcohil c <003>; and the atom of fluor can occupy any available position. It consists of the reaction of 3,4-methylendioxypenol with a derivative of formula (II) pyridine, where r is the same as in formula (I), and x is halogen, group ester or hydroxyl. When x is chlorine or ester group, the reaction is carried out in methanol, in the presence of sodium at a temperature between 0ºc and lade reflux. When x is hydroxyl the reaction is carried out through a coupling reagent at a temperature between 160ºc and 180ºc. These compounds have pharmacological applications as antidepressive and anti-perkinsonian agents. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES504997A ES8301974A3 (en) | 1981-08-26 | 1981-08-26 | A procedure for the preparation of a 4-fluorofenil-piperidine replaced in position 3 (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES504997A ES8301974A3 (en) | 1981-08-26 | 1981-08-26 | A procedure for the preparation of a 4-fluorofenil-piperidine replaced in position 3 (Machine-translation by Google Translate, not legally binding) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES504997A0 ES504997A0 (en) | 1983-01-01 |
| ES8301974A3 true ES8301974A3 (en) | 1983-01-01 |
Family
ID=8482885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES504997A Expired ES8301974A3 (en) | 1981-08-26 | 1981-08-26 | A procedure for the preparation of a 4-fluorofenil-piperidine replaced in position 3 (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8301974A3 (en) |
-
1981
- 1981-08-26 ES ES504997A patent/ES8301974A3/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES504997A0 (en) | 1983-01-01 |
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