ES8304135A3 - Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8304135A3 ES8304135A3 ES504202A ES504202A ES8304135A3 ES 8304135 A3 ES8304135 A3 ES 8304135A3 ES 504202 A ES504202 A ES 504202A ES 504202 A ES504202 A ES 504202A ES 8304135 A3 ES8304135 A3 ES 8304135A3
- Authority
- ES
- Spain
- Prior art keywords
- benzhydrylpiperazines
- translation
- procedure
- obtaining
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the obtaining of benzhydrylpiperazines and their physiologically compatible acid addition salts from formula (I), in which r can be one of various types of radicals. It consists in the reaction of benzhydrylpiperazine with the halogenuro of formula rx, in which x is chlorine, bromine or iodine and r has the same meaning as in formula (I). The reaction is carried out in an inert solution, in the presence of an alcali, through heating in a water bath. These compounds have pharmacological applications for their vasodilator and spasmolitic effects. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES504202A ES8304135A3 (en) | 1981-07-06 | 1981-07-06 | Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES504202A ES8304135A3 (en) | 1981-07-06 | 1981-07-06 | Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) |
Publications (2)
Publication Number | Publication Date |
---|---|
ES504202A0 ES504202A0 (en) | 1983-01-01 |
ES8304135A3 true ES8304135A3 (en) | 1983-01-01 |
Family
ID=8482735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504202A Expired ES8304135A3 (en) | 1981-07-06 | 1981-07-06 | Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8304135A3 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004089377A1 (en) * | 2003-04-08 | 2004-10-21 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6943168B2 (en) | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US7186726B2 (en) | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
-
1981
- 1981-07-06 ES ES504202A patent/ES8304135A3/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6943168B2 (en) | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US6949554B2 (en) | 1998-06-30 | 2005-09-27 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6951862B2 (en) | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US7064128B2 (en) | 1998-06-30 | 2006-06-20 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
US7186726B2 (en) | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
US7666865B2 (en) | 1998-06-30 | 2010-02-23 | Neuromed Pharmaceuticals Ltd. | Calcium channel blockers |
WO2004089377A1 (en) * | 2003-04-08 | 2004-10-21 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
Also Published As
Publication number | Publication date |
---|---|
ES504202A0 (en) | 1983-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19971103 |