ES8304135A3 - Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8304135A3
ES8304135A3 ES504202A ES504202A ES8304135A3 ES 8304135 A3 ES8304135 A3 ES 8304135A3 ES 504202 A ES504202 A ES 504202A ES 504202 A ES504202 A ES 504202A ES 8304135 A3 ES8304135 A3 ES 8304135A3
Authority
ES
Spain
Prior art keywords
benzhydrylpiperazines
translation
procedure
obtaining
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504202A
Other languages
Spanish (es)
Other versions
ES504202A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES504202A priority Critical patent/ES8304135A3/en
Publication of ES504202A0 publication Critical patent/ES504202A0/en
Publication of ES8304135A3 publication Critical patent/ES8304135A3/en
Expired legal-status Critical Current

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Abstract

Procedure for the obtaining of benzhydrylpiperazines and their physiologically compatible acid addition salts from formula (I), in which r can be one of various types of radicals. It consists in the reaction of benzhydrylpiperazine with the halogenuro of formula rx, in which x is chlorine, bromine or iodine and r has the same meaning as in formula (I). The reaction is carried out in an inert solution, in the presence of an alcali, through heating in a water bath. These compounds have pharmacological applications for their vasodilator and spasmolitic effects. (Machine-translation by Google Translate, not legally binding)
ES504202A 1981-07-06 1981-07-06 Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding) Expired ES8304135A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES504202A ES8304135A3 (en) 1981-07-06 1981-07-06 Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES504202A ES8304135A3 (en) 1981-07-06 1981-07-06 Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
ES504202A0 ES504202A0 (en) 1983-01-01
ES8304135A3 true ES8304135A3 (en) 1983-01-01

Family

ID=8482735

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504202A Expired ES8304135A3 (en) 1981-07-06 1981-07-06 Procedure for obtaining benzhydrylpiperazines. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES8304135A3 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004089377A1 (en) * 2003-04-08 2004-10-21 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties
US6943168B2 (en) 1998-06-30 2005-09-13 Neuromed Technologies Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US7186726B2 (en) 1998-06-30 2007-03-06 Neuromed Pharmaceuticals Ltd. Preferentially substituted calcium channel blockers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943168B2 (en) 1998-06-30 2005-09-13 Neuromed Technologies Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US6949554B2 (en) 1998-06-30 2005-09-27 Neuromed Technologies Inc. Calcium channel blockers comprising two benzhydril moieties
US6951862B2 (en) 1998-06-30 2005-10-04 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties
US7064128B2 (en) 1998-06-30 2006-06-20 Neuromed Technologies, Inc. Preferentially substituted calcium channel blockers
US7186726B2 (en) 1998-06-30 2007-03-06 Neuromed Pharmaceuticals Ltd. Preferentially substituted calcium channel blockers
US7666865B2 (en) 1998-06-30 2010-02-23 Neuromed Pharmaceuticals Ltd. Calcium channel blockers
WO2004089377A1 (en) * 2003-04-08 2004-10-21 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties

Also Published As

Publication number Publication date
ES504202A0 (en) 1983-01-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103