ES8300117A1 - Procedimiento de produccion de 20-deoxo-4-semicaroriltilomiao de una sal de la misma. - Google Patents

Procedimiento de produccion de 20-deoxo-4-semicaroriltilomiao de una sal de la misma.

Info

Publication number
ES8300117A1
ES8300117A1 ES503606A ES503606A ES8300117A1 ES 8300117 A1 ES8300117 A1 ES 8300117A1 ES 503606 A ES503606 A ES 503606A ES 503606 A ES503606 A ES 503606A ES 8300117 A1 ES8300117 A1 ES 8300117A1
Authority
ES
Spain
Prior art keywords
hydrogen
image
alkanoyl
deformyltylosin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES503606A
Other languages
English (en)
Other versions
ES503606A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12026979A external-priority patent/JPS5655399A/ja
Priority claimed from JP14664279A external-priority patent/JPS5671099A/ja
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of ES8300117A1 publication Critical patent/ES8300117A1/es
Publication of ES503606A0 publication Critical patent/ES503606A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO DE PRODUCCION DE 20-DEOXO-4-SEMICAROSILTILOSINA O DE UNA SAL DE LA MISMA. CONSISTE EN REDUCIR EN GRUPO -CHO EN LA POSICION 19 DE LA TILOSINA AL GRUPO CH2OH, DESHIDROXILAR EL GRUPO CH2OH PARA OBTENER 20-DEOXOTILOSINA Y LA DE -4ELEVAO,-MICAROSILACION DE LA 20-DEOXITILOSINA OBTENIDA CON ACIDO DILUIDO. LA DE-4 ELEVADO,-MICAROSILACION DE LA 2O-DEOXOTILOSINA PUEDE EFECTUARSE MEDIANTE HIDROLIZACION PUEDE DETERMINARSE SUPERVISANDO MEDIANTE CROMATOGRAFIA EN CAPA DELGADA DE GEL DE SILICE Y PUEDE CONCLUIRSE OBSERVANDO LA DESAPARICION DE 20-DEOXOTILOSINA. ACTIVIDAD ANTIBACTERIANA.
ES503606A 1979-09-19 1981-07-01 Procedimiento de produccion de 20-deoxo-4-semicaroriltilomiao de una sal de la misma. Granted ES503606A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12026979A JPS5655399A (en) 1979-09-19 1979-09-19 Deformyltylosin derivative
JP14664279A JPS5671099A (en) 1979-11-13 1979-11-13 20-deoxodesmycosin

Publications (2)

Publication Number Publication Date
ES8300117A1 true ES8300117A1 (es) 1982-10-01
ES503606A0 ES503606A0 (es) 1982-10-01

Family

ID=26457883

Family Applications (2)

Application Number Title Priority Date Filing Date
ES495214A Granted ES495214A0 (es) 1979-09-19 1980-09-19 Procedimiento para la obtencion de nuevos derivados defor- miltilosinos
ES503606A Granted ES503606A0 (es) 1979-09-19 1981-07-01 Procedimiento de produccion de 20-deoxo-4-semicaroriltilomiao de una sal de la misma.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES495214A Granted ES495214A0 (es) 1979-09-19 1980-09-19 Procedimiento para la obtencion de nuevos derivados defor- miltilosinos

Country Status (8)

Country Link
US (1) US4345069A (es)
CH (1) CH645650A5 (es)
DE (1) DE3033032A1 (es)
ES (2) ES495214A0 (es)
FR (1) FR2465747A1 (es)
GB (1) GB2058765B (es)
IT (1) IT1141057B (es)
NL (1) NL8004922A (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304856A (en) * 1980-11-10 1981-12-08 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin
JPS57154197A (en) * 1981-03-16 1982-09-22 Toyo Jozo Co Ltd Deoxydesmycosin
GB2102793B (en) * 1981-06-23 1984-10-10 Toyo Jozo Kk Deoxy-19-deformyl-desmycosins
AU551142B2 (en) * 1981-07-09 1986-04-17 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Tylosin derivatives
JPS58146595A (ja) * 1982-02-25 1983-09-01 Satoshi Omura マクロライド系抗生物質
US4436733A (en) 1982-03-03 1984-03-13 Eli Lilly And Company 4"- And 3-ester derivatives of DMT and DMOT
US4450237A (en) * 1982-05-03 1984-05-22 Pfizer Inc. Streptomyces albus subspecies indicus
US4411892A (en) * 1982-05-03 1983-10-25 Pfizer Inc. Tylosin macrolide antibiotics from streptomyces
US4423148A (en) 1982-07-02 1983-12-27 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
US4528369A (en) * 1982-07-02 1985-07-09 Eli Lilly And Company 20-Dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
US4820695A (en) * 1982-09-13 1989-04-11 Eli Lilly And Company C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics
JPS59141596A (ja) * 1983-02-03 1984-08-14 Toyo Jozo Co Ltd ３−ｏ−アシル−４″−デオキシデスマイコシン誘導体およびその製法
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
US4629786A (en) * 1983-02-28 1986-12-16 Eli Lilly And Company C-20- and C-23 modified macrolide derivatives
US4468511A (en) * 1983-02-28 1984-08-28 Eli Lilly And Company C-20- And C-23-Modified macrolide derivatives
US4581346A (en) * 1984-07-12 1986-04-08 Eli Lilly And Company Macrolide derivatives
JPS62103098A (ja) * 1985-05-13 1987-05-13 Microbial Chem Res Found タイロシン誘導体
EP0262903A3 (en) * 1986-09-29 1988-11-02 Eli Lilly And Company New acyl derivatives of 20-modified tylosin and desmycosin compounds
JPS6388180A (ja) * 1986-09-30 1988-04-19 Toyo Jozo Co Ltd ４”−デオキシ−３”−デメトキシ−３”−メチレンデスマイコシン誘導体およびその製造中間体
SI8710674B (sl) * 1987-04-14 1998-06-30 Pliva Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina
US4962146A (en) * 1987-04-29 1990-10-09 Schering Corporation 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives
US5168052A (en) * 1988-03-28 1992-12-01 Eli Lilly And Company Method for producing 20-deoxotylosin
CA1312858C (en) * 1988-06-13 1993-01-19 Sumio Umezawa 3-deoxy mycaminosyl tylonolide derivatives
FR2646081A1 (es) * 1989-04-20 1990-10-26 Adir
US5140014A (en) * 1989-11-13 1992-08-18 Abbott Laboratories Rosaramicin derivatives and method of treating bacterial infections
AU2002230386A1 (en) * 2000-09-25 2002-04-29 Kosan Biosciences, Inc. Sixteen-membered macrolide compounds
WO2015138458A1 (en) 2014-03-11 2015-09-17 Abbvie Inc. 4"-0-substituted tylosin a derivatives
CN110684065B (zh) * 2019-10-24 2020-11-20 中牧实业股份有限公司 3-乙酰去碳霉糖泰乐菌素药用盐的制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321368A (en) * 1963-09-13 1967-05-23 American Cyanamid Co Production of antibiotic am-684 from tylosin
US3769273A (en) * 1971-10-20 1973-10-30 Lilly Co Eli Bis-urea adducts of macrolide antibiotics

Also Published As

Publication number Publication date
GB2058765B (en) 1984-02-29
IT1141057B (it) 1986-10-01
FR2465747B1 (es) 1983-11-18
GB2058765A (en) 1981-04-15
DE3033032A1 (de) 1981-04-16
IT8024738A0 (it) 1980-09-18
ES8205793A1 (es) 1982-07-01
FR2465747A1 (fr) 1981-03-27
NL8004922A (nl) 1981-03-23
CH645650A5 (de) 1984-10-15
US4345069A (en) 1982-08-17
ES495214A0 (es) 1982-07-01
DE3033032C2 (es) 1988-02-18
ES503606A0 (es) 1982-10-01

Similar Documents

Publication Publication Date Title
ES8205793A1 (es) Procedimiento para la obtencion de nuevos derivados defor- miltilosinos
IE782130L (en) Imidazolidinones
ES468475A1 (es) Procedimiento para la preparacion de derivados de cefem
DE69317877D1 (en) 4''-deoxyerythromycinderivate
ES8602751A1 (es) Procedimiento para la preparacion de derivados de pirimidina
ES8700262A1 (es) Un compuesto
ATE15048T1 (de) 4''-epi erythromycin a und seine derivate brauchbar wie antibakterielle mittel.
ES8609336A1 (es) Un procedimiento para la preparacion de -1-metilcarbapenems.
SE7907547L (sv) 3", 4"-diacyltylosinderivat
ES2007419A6 (es) Un procedimiento para la preparacion de un glicosido de antraciclina.
ES8600640A1 (es) Procedimiento para la produccion de un antibiotico polieterico
ES449068A1 (es) Procedimiento para preparar derivados de isoxazol.
AU524737B2 (en) Aminoglycosides derived from desoxystreptamine
ES461688A1 (es) Un procedimiento para la preparacion de nuevos compuestos decefalosporina.
IE811626L (en) Anthracycline glycosides
ES8704951A1 (es) Un procedimiento para la preparacion de nuevos derivados penem.
AU7111581A (en) Imidazole derivatives
ES469450A1 (es) Ÿun procedimiento para la preparacion de bencilpirimidinasŸ
ES8601931A1 (es) Procedimiento para preparar imidazoles y triazoles con es- tructura de enoleter
ES8402845A1 (es) "procedimiento para la preparacion de 6b,7b-metilen-17x-pregn-4-en-21,17-carbolactonas"
IE780849L (en) Thienamycin derivatives

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203