ES8205191A1 - Procedimiento para la obtencion de derivados de anilina - Google Patents

Procedimiento para la obtencion de derivados de anilina

Info

Publication number
ES8205191A1
ES8205191A1 ES498351A ES498351A ES8205191A1 ES 8205191 A1 ES8205191 A1 ES 8205191A1 ES 498351 A ES498351 A ES 498351A ES 498351 A ES498351 A ES 498351A ES 8205191 A1 ES8205191 A1 ES 8205191A1
Authority
ES
Spain
Prior art keywords
aniline derivatives
processes
production
pharmaceutical preparations
preparations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498351A
Other languages
English (en)
Other versions
ES498351A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES498351A0 publication Critical patent/ES498351A0/es
Publication of ES8205191A1 publication Critical patent/ES8205191A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ANILINA, ASI COMO DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES DE FORMULA AR-N(CH3)-R, EN LA QUE AR ES FENILO SUSTITUIDO Y R PUEDE SER UNO DE VARIOS RADICALES. CONSISTE EN LA REACCION DE UNA AMINA DE FORMULA AR-NHCH3, O UNA DE SUS SALES, CON UN COMPUESTO DE FORMULA X-R, EN LAS QUE AR Y R TIENEN EL MISMO SIGNIFICADO ANTERIOR. LA REACCION SE LLEVA A CABO EN CONDICIONES DE N-ALQUILACION, EN PRESENCIA O AUSENCIA DE UN DISOLVENTE ORGANICO INERTE, A TEMPERATURAS COMPRENDIDAS ENTRE 0 Y 250 GRADOS CENTIGRADOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIDEPRESIVOS Y COMO INTERMEDIOS PARA LA OBTENCION DE OTROS COMPUESTOS ACTIVOS COMO MEDICAMENTOS.
ES498351A 1980-01-08 1981-01-07 Procedimiento para la obtencion de derivados de anilina Expired ES8205191A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803000441 DE3000441A1 (de) 1980-01-08 1980-01-08 Anilinderivate,,diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES498351A0 ES498351A0 (es) 1982-06-01
ES8205191A1 true ES8205191A1 (es) 1982-06-01

Family

ID=6091666

Family Applications (4)

Application Number Title Priority Date Filing Date
ES498351A Expired ES8205191A1 (es) 1980-01-08 1981-01-07 Procedimiento para la obtencion de derivados de anilina
ES509188A Granted ES509188A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.
ES509187A Granted ES509187A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.
ES509186A Granted ES509186A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES509188A Granted ES509188A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.
ES509187A Granted ES509187A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.
ES509186A Granted ES509186A0 (es) 1980-01-08 1982-01-29 Procedimiento para la obtencion de derivados de anilina.

Country Status (11)

Country Link
EP (1) EP0031910B1 (es)
JP (1) JPS56100744A (es)
AT (1) ATE3031T1 (es)
AU (1) AU539617B2 (es)
CA (1) CA1161844A (es)
DE (2) DE3000441A1 (es)
ES (4) ES8205191A1 (es)
HU (1) HU183282B (es)
IL (1) IL61868A (es)
YU (1) YU326880A (es)
ZA (1) ZA81100B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW198008B (es) * 1991-04-08 1993-01-11 Green Cross Corp

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2742174A1 (de) * 1977-09-20 1979-03-29 Bayer Ag Verfahren zur herstellung von aminen
ZA793568B (en) * 1978-07-26 1981-02-25 Duphar Int Res Algicidal composition

Also Published As

Publication number Publication date
IL61868A (en) 1983-11-30
AU6603781A (en) 1981-07-16
ES8301880A1 (es) 1982-12-16
ES498351A0 (es) 1982-06-01
EP0031910B1 (de) 1983-04-13
ES8306471A1 (es) 1983-06-01
HU183282B (en) 1984-04-28
CA1161844A (en) 1984-02-07
JPS56100744A (en) 1981-08-12
ES8306993A1 (es) 1983-06-16
ES509187A0 (es) 1982-12-16
ES509188A0 (es) 1983-06-16
ZA81100B (en) 1982-01-27
AU539617B2 (en) 1984-10-11
ATE3031T1 (de) 1983-04-15
YU326880A (en) 1983-12-31
DE3062786D1 (en) 1983-05-19
EP0031910A1 (de) 1981-07-15
ES509186A0 (es) 1983-06-01
DE3000441A1 (de) 1981-07-09

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