ES8202823A1 - Procedimiento para preparar derivados de ergolina - Google Patents

Procedimiento para preparar derivados de ergolina

Info

Publication number
ES8202823A1
ES8202823A1 ES497114A ES497114A ES8202823A1 ES 8202823 A1 ES8202823 A1 ES 8202823A1 ES 497114 A ES497114 A ES 497114A ES 497114 A ES497114 A ES 497114A ES 8202823 A1 ES8202823 A1 ES 8202823A1
Authority
ES
Spain
Prior art keywords
production
pharmaceutical compositions
compositions containing
ergoline derivatives
ergoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497114A
Other languages
English (en)
Other versions
ES497114A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES497114A0 publication Critical patent/ES497114A0/es
Publication of ES8202823A1 publication Critical patent/ES8202823A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ERGOLINA, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS RADICALES. CONSISTE EN LA REACCION DE ALQUILACION DE UN COMPUESTO DE FORMULA (II). LA REACCION SE LLEVA A CABO DE MODO CONVENCIONAL, CON UN COMPUESTO DE FORMULA R-Y, EN LA QUE Y ES CLORO, BROMO O YODO Y R ES EL MISMO QUE EN LA FORMULA (I), EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE Y A TEMPERATURAS ENTRE 20C Y 100 C. TAMBIEN SE PUEDEN OBTENER POR REACCION DE CONDENSACION DE UN COMPUESTO DE FORMULA (III) CON UN COMPUESTO DE FORMULA (IV), EN LAS QUE X ES UN GRUPO QUE SE SEPARA Y M ES HIDROGENO O UN METAL ALCALINO.
ES497114A 1979-11-27 1980-11-25 Procedimiento para preparar derivados de ergolina Expired ES8202823A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1052679 1979-11-27

Publications (2)

Publication Number Publication Date
ES497114A0 ES497114A0 (es) 1982-02-16
ES8202823A1 true ES8202823A1 (es) 1982-02-16

Family

ID=4364160

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497114A Expired ES8202823A1 (es) 1979-11-27 1980-11-25 Procedimiento para preparar derivados de ergolina

Country Status (16)

Country Link
JP (1) JPS5690087A (es)
AU (1) AU6468980A (es)
BE (1) BE886308A (es)
DE (1) DE3043210A1 (es)
DK (1) DK503580A (es)
ES (1) ES8202823A1 (es)
FI (1) FI803635L (es)
FR (1) FR2470131A1 (es)
GB (1) GB2065113A (es)
IL (1) IL61562A0 (es)
IT (1) IT8050243A0 (es)
NL (1) NL8006461A (es)
NZ (1) NZ195641A (es)
PT (1) PT72104B (es)
SE (1) SE8008234L (es)
ZA (1) ZA807420B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200603B (it) * 1985-04-04 1989-01-27 Poli Ind Chimica Spa Composizione farmaceutiche ad attivita dopaminergica

Also Published As

Publication number Publication date
NZ195641A (en) 1984-09-28
PT72104B (fr) 1982-01-28
DE3043210A1 (de) 1981-08-27
FR2470131A1 (fr) 1981-05-29
GB2065113A (en) 1981-06-24
SE8008234L (sv) 1981-05-28
ES497114A0 (es) 1982-02-16
AU6468980A (en) 1981-06-04
ZA807420B (en) 1982-07-28
FI803635L (fi) 1981-05-28
DK503580A (da) 1981-05-28
BE886308A (fr) 1981-05-25
JPS5690087A (en) 1981-07-21
IT8050243A0 (it) 1980-11-25
IL61562A0 (en) 1980-12-31
NL8006461A (nl) 1981-07-01
PT72104A (fr) 1980-12-01

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