ES8202800A1 - Metodo para producir derivados del 4-metil-5-(2-aminoetil)- tiometil-imidazol que tienen actividad terapeutica - Google Patents

Metodo para producir derivados del 4-metil-5-(2-aminoetil)- tiometil-imidazol que tienen actividad terapeutica

Info

Publication number
ES8202800A1
ES8202800A1 ES500454A ES500454A ES8202800A1 ES 8202800 A1 ES8202800 A1 ES 8202800A1 ES 500454 A ES500454 A ES 500454A ES 500454 A ES500454 A ES 500454A ES 8202800 A1 ES8202800 A1 ES 8202800A1
Authority
ES
Spain
Prior art keywords
derivatives
imidazole
thiomethyl
aminoethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500454A
Other languages
English (en)
Other versions
ES500454A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8202800A1 publication Critical patent/ES8202800A1/es
Publication of ES500454A0 publication Critical patent/ES500454A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 4-METIL-5-2-(2-AMINOETIL)-TIOMETIL-IMIDAZOL, DE FORMULA (I), EN LA QUE R1 ES HIDROGENO METILO O ESTILO; Y T2 Y EVENTUALMENTE R7 ES UN RADICAL ACILICO DE UN ACIDO ANTIINFLAMATORIO, ASI COMO DE LAS SALES FISIOLOGICAMENTE COMPATIBLES, COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS POR SUS ACTIVIDADES ANTIINFLAMATORIAS, ANTIPIRETICA Y ANALGESICA. CONSISTE EN LA REACCION DEL 4-METIL-5-((2-AMINOETIL)-TIOMETIL))-IMIDAZOL, O SU CLOHIDRATO, CON UN DERIVADO ACTIVO DEL ACIDO ANTIINFLAMATORIO, TAL COMO EL CLORURO DE ACILO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE AL CLORURO DE ACILO O EN DISOLUCION ACUOSA, EN PRESENCIA DE UNA BASE ACEPTADORA DEL CLORURO DE HIDROGENO, A UNA TEMPERATURA ENTRE 0C Y 40C.
ES500454A 1980-03-18 1981-03-17 Metodo para producir derivados del 4-metil-5-(2-aminoetil)- tiometil-imidazol que tienen actividad terapeutica Granted ES500454A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8020734A IT8020734A0 (it) 1980-03-18 1980-03-18 Quadrata (2 aminoetil)-tiometilderivati del 4-metil-5 aperta par.chiusa par. quadrata-imidazolo adattivita' terapeutica.

Publications (2)

Publication Number Publication Date
ES8202800A1 true ES8202800A1 (es) 1982-02-01
ES500454A0 ES500454A0 (es) 1982-02-01

Family

ID=11171242

Family Applications (1)

Application Number Title Priority Date Filing Date
ES500454A Granted ES500454A0 (es) 1980-03-18 1981-03-17 Metodo para producir derivados del 4-metil-5-(2-aminoetil)- tiometil-imidazol que tienen actividad terapeutica

Country Status (5)

Country Link
US (1) US4347373A (es)
EP (1) EP0036684A1 (es)
JP (1) JPS56140973A (es)
ES (1) ES500454A0 (es)
IT (1) IT8020734A0 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0627120B2 (ja) * 1986-11-07 1994-04-13 三井石油化学工業株式会社 新規なα−クロロケトン誘導体および製造法
JP2000036178A (ja) 1998-07-17 2000-02-02 Fuji Photo Film Co Ltd 磁気テープカートリッジ
WO2007002135A2 (en) * 2005-06-21 2007-01-04 Trace Bio Analytics, Llc Non-signal imidazole reagents for mass spectrometry analysis of phosphomonoesters

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2301532A (en) * 1938-08-18 1942-11-10 Parke Davis & Co Biological product and process of obtaining same
CH233730A (de) * 1942-04-17 1944-08-15 Ag Sandoz Verfahren zur Darstellung eines aromatischen Carbonsäureamids.
GB1574214A (en) * 1976-03-11 1980-09-03 Smith Kline French Lab Amidines

Also Published As

Publication number Publication date
JPS56140973A (en) 1981-11-04
US4347373A (en) 1982-08-31
IT8020734A0 (it) 1980-03-18
EP0036684A1 (en) 1981-09-30
ES500454A0 (es) 1982-02-01

Similar Documents

Publication Publication Date Title
FI97381C (fi) Menetelmä korkeaa verenpainetta alentavien substituoitujen pyrroli-, pyratsoli- ja triatsoliyhdisteiden valmistamiseksi
ES480542A1 (es) Metodo para producir derivados de imidazol.
ES483700A1 (es) Un procedimiento para preparar 2-nitroimidazols.
ES8203883A1 (es) Un procedimiento para la preparacion de derivados de imida- zol
ATE15198T1 (de) Blutdrucksenkende 1-substituierte spiro(piperidin-oxobenzoxazine).
AU567100B2 (en) Imidazole and triazole fungicides
ES8706654A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzotiazina
ATE19870T1 (de) 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.
JPS5750989A (en) Imidazole compound
ES8202800A1 (es) Metodo para producir derivados del 4-metil-5-(2-aminoetil)- tiometil-imidazol que tienen actividad terapeutica
ES455691A1 (es) Procedimiento para la produccion de derivados de piperacina.
ES477785A1 (es) Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.
ES8106150A1 (es) Procedimiento para preparar 5-(clorofenil)-6h-1,3,4-tiadia- zina-2-aminas
IE56917B1 (en) N-sulphenylated hydantoins,a process for their preparation and their use as microbicides
ATE3035T1 (de) Azolyl-alkenole, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide.
ES8504734A1 (es) Procedimiento para la obtencion de derivados de imidazol conteniendo azufre
ATE10370T1 (de) Benzothiazinderivate, verfahren zu ihrer herstellung und ihre verwendung.
FR2383938A1 (fr) Acides acetiques disubstitues, employes pour la synthese de composes de cephalosporine
GB1223217A (en) 3-substituted-benzyl cyclopropanecarboxylates
ES483699A1 (es) Un procedimiento para la preparacion del derivado acido 1h- indazol-3-ilacetico
DE3569733D1 (en) Use of some 2-û2-û4-phenyl-1-piperazinyl¨ethyl¨-1h-naphth-û1,2-d¨imidazole derivatives and their pharmaceutically acceptable salts for the manufacture of a medicament for the treatment of cardiovascular diseases
ES8104265A1 (es) Un procedimiento para la preparacion de nuevas bencenosulfi-namidas
ES8303363A1 (es) "metodo de preparar compuestos metilquinoxalin-1,4-dioxidicos".
ES8304556A1 (es) Procedimiento para preparar 5-(opcionalmente fenil sustitui-das)-6h-1,3,4-tiadiacin-2-aminas
DE69501810D1 (de) Verwendung von 5-Thia-1,4-Diazabicyclo [4.2.0] Octane-3,8-dioxo Verbindungen in der Antitumor-Therapie