ES8202029A1 - Procedimiento para preparar un producto con actividad de ti-po fibronectina - Google Patents

Procedimiento para preparar un producto con actividad de ti-po fibronectina

Info

Publication number
ES8202029A1
ES8202029A1 ES500122A ES500122A ES8202029A1 ES 8202029 A1 ES8202029 A1 ES 8202029A1 ES 500122 A ES500122 A ES 500122A ES 500122 A ES500122 A ES 500122A ES 8202029 A1 ES8202029 A1 ES 8202029A1
Authority
ES
Spain
Prior art keywords
blood plasma
fibronectin
antihemophilic factor
solution
plasma fractionation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500122A
Other languages
English (en)
Other versions
ES500122A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Cutter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cutter Laboratories Inc filed Critical Cutter Laboratories Inc
Publication of ES8202029A1 publication Critical patent/ES8202029A1/es
Publication of ES500122A0 publication Critical patent/ES500122A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN PRODUCTO CON ACTIVIDAD DE TIPO FIBRONECTINA. SE AISLA UNA FRACCION DE PLASMA SANGUINEO CONTENIENDO FIBRONECTINA Y FACTOR ANTIHEMOFILICO A PARTIR DE PLASMA SANGUINEO. SE FORMA UNA SOLUCION DE DICHA FRACCION DE PLASMA SANGUINEO EN UN MEDIO ACUOSO. SE ACIDIFICA Y SE ENFRIA LA SOLUCION A UN PH Y A UNA TEMPERATURA SUFICIENTES PARA FORMAR UN PRECIPITADO ACIDO-FRIO QUE CONTIENE UNA PROPORCION PRINCIPAL DE LA FIBRONECTINA DE DICHA FRACCION DE PLASMA SANGUINEO Y CONTENIENDO DICHA SOLUCION UNA PROPORCION PRINCIPAL DEL FACTOR ANTIHEMOFILICO DE LA FRACCION. SE SEPARA EL PRECIPITADO ACIDO-FRIO DE LA SOLUCION. SE UTILIZA COMO FUENTE DE FIBRONECTINA Y COMO SUSTITUTO DE LA MISMA.
ES500122A 1980-03-05 1981-03-05 Procedimiento para preparar un producto con actividad de ti-po fibronectina Granted ES500122A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/127,340 US4341764A (en) 1980-03-05 1980-03-05 Method of preparing fibronectin and antihemophilic factor

Publications (2)

Publication Number Publication Date
ES8202029A1 true ES8202029A1 (es) 1982-01-01
ES500122A0 ES500122A0 (es) 1982-01-01

Family

ID=22429606

Family Applications (1)

Application Number Title Priority Date Filing Date
ES500122A Granted ES500122A0 (es) 1980-03-05 1981-03-05 Procedimiento para preparar un producto con actividad de ti-po fibronectina

Country Status (9)

Country Link
US (1) US4341764A (es)
EP (1) EP0035202B1 (es)
JP (1) JPS56139418A (es)
AT (1) ATE15973T1 (es)
CA (1) CA1164342A (es)
DE (1) DE3172567D1 (es)
DK (1) DK156697C (es)
ES (1) ES500122A0 (es)
MX (1) MX7113E (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
JPS584074U (ja) * 1981-06-30 1983-01-11 井上　岱介 風車ネオン式検電器
DE3170868D1 (en) * 1981-10-12 1985-07-11 Armour Pharma Process for the preparation of highly purified antihemophilic factor
US4391749A (en) * 1981-10-19 1983-07-05 La Jolla Cancer Research Foundation Method for the purification of collagens
JPS5967228A (ja) * 1982-10-07 1984-04-16 Green Cross Corp:The 寒冷不溶性グロブリンの凍結乾燥方法
JPS59134732A (ja) * 1983-01-21 1984-08-02 Green Cross Corp:The フイブロネクチン・生理活性物質複合体の製造法
DE3318521A1 (de) * 1983-05-20 1984-11-22 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur herstellung eines antihaemophiliefaktor-konzentrats
EP0142109B1 (en) * 1983-11-04 1992-06-17 Ralph Silverman Macromolecules extracted from cultured mesenchymal cells for the treatment of degenerative diseases
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
AT385658B (de) * 1985-03-28 1988-05-10 Serotherapeutisches Inst Wien Verfahren zur herstellung einer fuer die anwendung beim menschen geeigneten fibronektinloesung
US4587122A (en) * 1985-04-23 1986-05-06 The Green Cross Corporation Fibronectin-dextran-drug complex and method of preparation thereof
US4894328A (en) * 1986-03-26 1990-01-16 Board Of Regents, The University Of Texas System Immunodiagnostic test for syphilis and other treponemal infections
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
US5629291A (en) * 1992-01-31 1997-05-13 La Jolla Cancer Research Foundation Methods of modulating fibronectin extracellular matrix assembly
US5453489A (en) * 1992-01-31 1995-09-26 La Jolla Cancer Research Foundation Polypeptide fragments of fibronectin which can modulate extracellular matrix assembly
US6528483B2 (en) * 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US7112320B1 (en) * 1995-06-07 2006-09-26 Andre Beaulieu Solid wound healing formulations containing fibronectin
US5821220A (en) * 1995-06-07 1998-10-13 Andre Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
NZ505424A (en) 1998-01-23 2002-09-27 Csl Ltd Purification of fibrinogen
BR0008405B1 (pt) 1999-02-22 2014-04-22 Baxter Int Composição de fator viii formulada sem a adição de albumina, uso de uma composição de fator viii, e, método de liofilizar uma formulação farmacêutica aquosa
AU779126B2 (en) * 1999-12-23 2005-01-06 Csl Limited Separation of fibrinogen from plasma proteases
DE60042343D1 (de) * 1999-12-23 2009-07-16 Csl Ltd Abtrennung von fibrinogen von plasmaproteasen
DE102004044419B4 (de) 2004-09-14 2010-04-15 Biotest Ag Verfahren zur Aufreinigung eines von Willebrand Faktors mittels Hydroxylapatit-Durchlaufchromatographie
DE102004044429B4 (de) * 2004-09-14 2009-04-30 Biotest Ag Verfahren zur Herstellung einer Zusammensetzung enthaltend von Willebrand Faktor
US20100168018A1 (en) * 2008-11-07 2010-07-01 Baxter International Inc. Factor viii formulations
BRPI1010975B1 (pt) 2009-05-25 2021-08-24 H. Lundbeck A/S Métodos para preparar nalmefeno a partir de naltrexona em uma reação de wittig e para isolar o nalmefeno
IL213864A0 (en) 2011-06-30 2011-08-31 Omrix Biopharmaceuticals Ltd Method for removing a lytic enzyme from a heterogeneous mixture
US8844879B2 (en) * 2011-12-12 2014-09-30 The Boeing Company Wing variable camber trailing edge tip
IL231230A0 (en) 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973002A (en) * 1974-04-12 1976-08-03 E. R. Squibb & Sons, Inc. Antihemophilic factor
US4170639A (en) * 1978-07-10 1979-10-09 Warner-Lambert Company Antihemophilic factor concentrate and its production
DE2848529A1 (de) * 1978-11-09 1980-05-29 Behringwerke Ag Verfahren zur herstellung des kaelteunloeslichen globulins und dieses enthaltende arzneimittel
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma

Also Published As

Publication number Publication date
DK98581A (da) 1981-09-06
EP0035202B1 (en) 1985-10-09
EP0035202A3 (en) 1982-09-01
DE3172567D1 (en) 1985-11-14
ATE15973T1 (de) 1985-10-15
DK156697C (da) 1990-02-05
JPS56139418A (en) 1981-10-30
MX7113E (es) 1987-06-29
US4341764A (en) 1982-07-27
CA1164342A (en) 1984-03-27
EP0035202A2 (en) 1981-09-09
DK156697B (da) 1989-09-25
ES500122A0 (es) 1982-01-01

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