GB1207477A - Plasma proteins solution - Google Patents

Plasma proteins solution

Info

Publication number
GB1207477A
GB1207477A GB2171469A GB2171469A GB1207477A GB 1207477 A GB1207477 A GB 1207477A GB 2171469 A GB2171469 A GB 2171469A GB 2171469 A GB2171469 A GB 2171469A GB 1207477 A GB1207477 A GB 1207477A
Authority
GB
United Kingdom
Prior art keywords
fraction
haemopigments
globulins
treated
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2171469A
Inventor
Anatoly Alexandrovich From
Anatoly Efimovich Kiselev
Alexandr Alexandrovi Nikitenko
Valentin Mikhailovich Rusanov
Nina Mikhailovna Kikvadze
Ljubov Nikolaevna Saraeanova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TS I GEMATOLOGII I PERELIVANIA
Original Assignee
TS I GEMATOLOGII I PERELIVANIA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TS I GEMATOLOGII I PERELIVANIA filed Critical TS I GEMATOLOGII I PERELIVANIA
Priority to GB2171469A priority Critical patent/GB1207477A/en
Publication of GB1207477A publication Critical patent/GB1207477A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4717—Plasma globulins, lactoglobulin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

1,207,477. Preparing plasma proteins. TSENTRALNY ORDENA LENINA INSTITUT GEMATOLOGII I PERELIVANIA KROVI. 29 April, 1969, No. 21714/69. Heading A5B. A method of preparing a stable solution of albumin and α- and #-globulin comprises fractionating a plasma or serum containing haemopigments to isolate a fraction containing albumin and α- and #-globulins, adding hydrogen peroxide to said fraction at a temperature not greater than 70‹C., maintaining the treated fraction at a temperature of not greater than 70‹C., to denature thermolabile globulins and haemopigments, and subsequently removing the denatured thermolabile globulins and haemopigments from the treated solution. To obtain the starting material, alcohol may be added to serum or plasma to a concentration of 8% and the precipitate which forms is discarded; the alcohol concentration is then raised to 25% to precipitate gamma-globulin which is removed; the solution is acidified to pH 6 and a further precipitate removed; then the alcohol content is raised to 40%, the pH adjusted to .4.8, and the desired fraction is precipitated. The material is redissolved and may be treated with from 0.01 to 0.1% of hydrogen peroxide.
GB2171469A 1969-04-29 1969-04-29 Plasma proteins solution Expired GB1207477A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2171469A GB1207477A (en) 1969-04-29 1969-04-29 Plasma proteins solution

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2171469A GB1207477A (en) 1969-04-29 1969-04-29 Plasma proteins solution

Publications (1)

Publication Number Publication Date
GB1207477A true GB1207477A (en) 1970-10-07

Family

ID=10167610

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2171469A Expired GB1207477A (en) 1969-04-29 1969-04-29 Plasma proteins solution

Country Status (1)

Country Link
GB (1) GB1207477A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152334B (en) * 1977-01-26 1988-02-22 Armour Pharma PROCEDURE FOR PREPARING AN INTRAVENOST SUBMITTED, PYROGEN FREE, STORAGE STABLE SERUM PROTEIN PREPARATION

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152334B (en) * 1977-01-26 1988-02-22 Armour Pharma PROCEDURE FOR PREPARING AN INTRAVENOST SUBMITTED, PYROGEN FREE, STORAGE STABLE SERUM PROTEIN PREPARATION

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee