GB1375811A - - Google Patents
Info
- Publication number
- GB1375811A GB1375811A GB1213873A GB1213873A GB1375811A GB 1375811 A GB1375811 A GB 1375811A GB 1213873 A GB1213873 A GB 1213873A GB 1213873 A GB1213873 A GB 1213873A GB 1375811 A GB1375811 A GB 1375811A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antigen
- protein
- solution
- precipitate
- march
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
- Y10S530/831—Cohn fractions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1375811 Removing hepatitis-associated antigen from solution USA GOVERNMENT OF 13 March 1973 [16 March 1972] 12138/73 Heading A5B A process for removing hepatitis-associated antigen from a solution comprising a proteinfraction containing the antigen comprises (a) maintaining the solubility of the antigen-containing protein by adjusting the pH to a value as far as possible from the isoelectric point but such as to permit precipitation of the hepatitisassociated antigen and not to denature the protein; (b) adding a solution, in a solvent which is physiologically tolerable on injection, of polyethylene glycol having a M.W. from 200 to 6000 at a concentration of from 12 to 30 grams of polyethylene glycol per 100 ml. of solution, thereby producing a precipitate containing the antigen, and (c) separating the precipitate from the solution. The protein may be extracted from a precipitate containing the protein and antigen by using a solvent having a pH removed from the isoelectric point of the protein.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23521172A | 1972-03-16 | 1972-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1375811A true GB1375811A (en) | 1974-11-27 |
Family
ID=22884566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1213873A Expired GB1375811A (en) | 1972-03-16 | 1973-03-13 |
Country Status (8)
Country | Link |
---|---|
US (1) | US3790552A (en) |
AT (1) | AT321465B (en) |
BE (1) | BE796770A (en) |
CA (1) | CA1061251A (en) |
DE (1) | DE2306107A1 (en) |
DK (1) | DK133292C (en) |
FR (1) | FR2175969B1 (en) |
GB (1) | GB1375811A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008100578A2 (en) * | 2007-02-14 | 2008-08-21 | Amgen Inc. | Method of isolating antibodies by precipitation |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3951937A (en) * | 1973-12-20 | 1976-04-20 | The Community Blood Council Of Greater New York, Inc. | Large scale purification of hepatitis type B antigen using polyethylene glycol |
DE2602892A1 (en) * | 1976-01-27 | 1977-07-28 | Community Blood Council | Highly purified hepatitis type B antigen from blood materials - by double pptn. with polyethylene glycol |
DK25877A (en) * | 1977-01-21 | 1978-08-15 | Nordisk Insulinlab | PROCEDURE FOR EXTRACTING PURE ALBUMIN FROM BLOOD PLASMA |
US4197238A (en) * | 1977-04-12 | 1980-04-08 | The Green Cross Corporation | Method of preparation of human albumin using polyethylene glycol |
DE2750045A1 (en) * | 1977-11-09 | 1979-05-10 | Behringwerke Ag | METHOD FOR REMOVING DETERGENTS FROM VIRUS ANTIGENS SUSPENSIONS |
US4164496A (en) * | 1978-08-23 | 1979-08-14 | American National Red Cross | Preparation of albumin using PEG and EDTA |
US4395395A (en) * | 1979-05-21 | 1983-07-26 | The United States Of America As Represented By The Department Of Health And Human Services | Detection of non-A, non-B hepatitis associated antigen |
FR2483779A1 (en) * | 1980-06-05 | 1981-12-11 | Synthelabo | PROCESS FOR ISOLATING VIRAL GLYCOPROTETIC ANTIGENS AND APPLICATION THEREOF TO VACCINE PREPARATION |
US4835257A (en) * | 1984-07-07 | 1989-05-30 | Armour Pharma Gmbh | Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer |
US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
US4684723A (en) * | 1985-09-11 | 1987-08-04 | Miles Laboratories, Inc. | Method of separating proteins from aqueous solutions |
US4833233A (en) * | 1987-08-20 | 1989-05-23 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Human serum albumin crystals and method of preparation |
US5525519A (en) * | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
AU2008214319A1 (en) * | 2007-02-06 | 2008-08-14 | Incept, Llc | Polymerization with precipitation of proteins for elution in physiological solution |
-
1972
- 1972-03-16 US US00235211A patent/US3790552A/en not_active Expired - Lifetime
-
1973
- 1973-02-08 DE DE2306107A patent/DE2306107A1/en active Pending
- 1973-02-15 DK DK82273*#A patent/DK133292C/en active
- 1973-03-01 AT AT184173A patent/AT321465B/en not_active IP Right Cessation
- 1973-03-13 FR FR7308875A patent/FR2175969B1/fr not_active Expired
- 1973-03-13 GB GB1213873A patent/GB1375811A/en not_active Expired
- 1973-03-14 BE BE128796A patent/BE796770A/en unknown
- 1973-03-16 CA CA166,295A patent/CA1061251A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008100578A2 (en) * | 2007-02-14 | 2008-08-21 | Amgen Inc. | Method of isolating antibodies by precipitation |
WO2008100578A3 (en) * | 2007-02-14 | 2008-10-16 | Amgen Inc | Method of isolating antibodies by precipitation |
Also Published As
Publication number | Publication date |
---|---|
US3790552A (en) | 1974-02-05 |
BE796770A (en) | 1973-07-02 |
DK133292B (en) | 1976-04-26 |
AT321465B (en) | 1975-04-10 |
DE2306107A1 (en) | 1973-09-27 |
CA1061251A (en) | 1979-08-28 |
DK133292C (en) | 1976-09-27 |
FR2175969B1 (en) | 1977-08-12 |
FR2175969A1 (en) | 1973-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |