ES8201313A1 - Metodo y su correspondiente aparato de exploracion de particulas. - Google Patents
Metodo y su correspondiente aparato de exploracion de particulas.Info
- Publication number
- ES8201313A1 ES8201313A1 ES497018A ES497018A ES8201313A1 ES 8201313 A1 ES8201313 A1 ES 8201313A1 ES 497018 A ES497018 A ES 497018A ES 497018 A ES497018 A ES 497018A ES 8201313 A1 ES8201313 A1 ES 8201313A1
- Authority
- ES
- Spain
- Prior art keywords
- particle
- orifice
- current
- produce
- size
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title abstract 6
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1022—Measurement of deformation of individual particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/103—Particle shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
APARATO PARA ANALISIS DE PARTICULAS POR EL PRINCIPIO DE DETECCION DE IMPEDANCIA. EN UNA VASIJA (22) TRANSPARENTE, CON UN SEPARADOR (28) CONICO, SE INTRODUCE UNA CORRIENTE LIQUIDA DE PARTICULAS POR UN TUBO (12) RODEADO DE UNA VAINA (14), POR DONDE CIRCULA AGUA A PRESION PARA CONDUCIR EN TRAYECTORIAS RECTAS LA CORRIENTE DE PARTICULAS EN EL LIQUIDO (20) DE LA VASIJA (22). UNOS EQUIPOS (46, 48, 56, 58) ELECTRICOS CREAN DOS CORRIENTES DE ALTA Y BAJA FRECUENCIA QUE SE EMPLEAN PARA MEDIR LA IMPEDANCIA DE LA CORRIENTE DE PARTICULAS, ANALIZANDOSE LOS DATOS OBTENIDOS, JUNTO CON LOS DATOS DE TAMAÑO DE PARTICULAS OBTENIDOS CON UN EQUIPO DE LASER ROJO (30, 34, 39, 40, 42, 43) EN UN CALCULADOR (60).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/096,945 US4298836A (en) | 1979-11-23 | 1979-11-23 | Particle shape determination |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8201313A1 true ES8201313A1 (es) | 1981-12-01 |
ES497018A0 ES497018A0 (es) | 1981-12-01 |
Family
ID=22259875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497018A Granted ES497018A0 (es) | 1979-11-23 | 1980-11-20 | Metodo y su correspondiente aparato de exploracion de particulas. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4298836A (es) |
JP (1) | JPS5686336A (es) |
AU (1) | AU540023B2 (es) |
BR (1) | BR8007591A (es) |
CA (1) | CA1151730A (es) |
CH (1) | CH639767A5 (es) |
DE (1) | DE3043814A1 (es) |
ES (1) | ES497018A0 (es) |
FR (1) | FR2470377A1 (es) |
GB (1) | GB2064133B (es) |
IT (1) | IT1148275B (es) |
NL (1) | NL8006326A (es) |
SE (1) | SE8008148L (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4420720A (en) * | 1981-06-29 | 1983-12-13 | Coulter Electronics, Inc. | Field focused particle sensing zone |
US4510438A (en) * | 1982-02-16 | 1985-04-09 | Coulter Electronics, Inc. | Coincidence correction in particle analysis system |
US4527114A (en) * | 1982-02-25 | 1985-07-02 | Coulter Electronics, Inc. | Electrical slit scanning apparatus |
DE3233055C2 (de) * | 1982-09-06 | 1994-07-28 | Coulter Electronics | Durchflußvorrichtung zur Untersuchung einzelner, in einer Flüssigkeit suspendierter Teilchen |
IT1179316B (it) * | 1984-04-19 | 1987-09-16 | Vittorio Prodi | Dispositivo per la separazione in classi granulometriche di particelle di aerosol |
IT1199393B (it) * | 1984-04-19 | 1988-12-30 | Vittorio Prodi | Dispositivo di tipo perfezionato per la separazione in classi granulometriche di particelle di aerosol |
EP0198670A3 (en) * | 1985-04-11 | 1989-08-23 | Nippon Steel Corporation | Measurement of sizes of particles in falling state |
US4760328A (en) * | 1986-05-05 | 1988-07-26 | Integrated Ionics, Inc. | Particle counter having electrodes and circuitry mounted on the pane of the orifice |
US4791355A (en) * | 1986-10-21 | 1988-12-13 | Coulter Electronics Inc. | Particle analyzer for measuring the resistance and reactance of a particle |
KR970007077B1 (ko) * | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | 광산란 기술을 이용한 다중-부분식별 분석 방법 |
US4895034A (en) * | 1987-07-28 | 1990-01-23 | Amherst Process Instruments, Inc. | Powder disperser for aerodynamic particle sizing system |
US4938592A (en) * | 1987-07-28 | 1990-07-03 | Amherst Process Instruments, Inc. | Beam forming and sensing apparatus for aerodynamic particle sizing system |
WO1992009682A1 (en) * | 1990-11-23 | 1992-06-11 | Coulter Corporation | Method and apparatus for screening microscopic cells utilizing light scatter techniques |
US5194909A (en) * | 1990-12-04 | 1993-03-16 | Tycko Daniel H | Apparatus and method for measuring volume and hemoglobin concentration of red blood cells |
US5503982A (en) * | 1993-09-30 | 1996-04-02 | Research Corporation Technologies, Inc. | Detection of an acute myocardial infarction in a patient |
JP3328032B2 (ja) * | 1993-11-04 | 2002-09-24 | シスメックス株式会社 | 粒子分析装置 |
GB2294772B (en) * | 1994-11-02 | 1999-04-14 | Haroun Mahgerefteh | Particle size distribution analyser |
US5522555A (en) * | 1994-03-01 | 1996-06-04 | Amherst Process Instruments, Inc. | Dry powder dispersion system |
JP3347495B2 (ja) * | 1994-11-14 | 2002-11-20 | シスメックス株式会社 | 粒子分析装置 |
US5817518A (en) * | 1995-12-18 | 1998-10-06 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
JP3587607B2 (ja) * | 1995-12-22 | 2004-11-10 | シスメックス株式会社 | 粒子測定装置およびその方法 |
AU714953B2 (en) * | 1995-12-29 | 2000-01-13 | Ian Basil Shine | Method for testing a cell sample |
GB9526684D0 (en) | 1995-12-29 | 1996-02-28 | Shine Thomas A | Method for testing a cell sample |
US5686309A (en) * | 1996-01-19 | 1997-11-11 | Coulter International Corp. | Method and apparatus for determination of hemoglobin content of individual red blood cells |
US5907240A (en) * | 1997-05-12 | 1999-05-25 | Cdc Technologies, Inc. | Method and apparatus for cell differentiation by measuring apparent cell size, membrane integrity and intracellular complexity |
CA2229528A1 (en) | 1998-02-13 | 1999-08-13 | Shailesh Mehta | Apparatus and method for analyzing particles |
US6699680B1 (en) | 1998-12-29 | 2004-03-02 | Ian Basil Shine | Method of determining a number of platelets |
US6323632B1 (en) * | 1999-08-13 | 2001-11-27 | Coulter International Corp. | Solid state RF oscillator-detector for flow cytometer |
US6204668B1 (en) | 1999-02-22 | 2001-03-20 | Coulter International Corp. | DC/RF blood cell detector using isolated bridge circuit having automatic amplitude and phase balance components |
US6587792B1 (en) * | 2000-01-11 | 2003-07-01 | Richard A. Thomas | Nuclear packing efficiency |
EP1476749A1 (en) * | 2002-02-14 | 2004-11-17 | McGill University | Device and method for determining parameters |
US7867778B2 (en) * | 2007-02-23 | 2011-01-11 | Visiongate, Inc. | Fluid focusing for positional control of a specimen for 3-D imaging |
JP5604862B2 (ja) * | 2009-01-09 | 2014-10-15 | ソニー株式会社 | 流路デバイス、複素誘電率測定装置及び誘電サイトメトリー装置 |
US20100198037A1 (en) * | 2009-01-30 | 2010-08-05 | Cole Steven W | Feedback sensor for real-time management of sickle cell disease |
CN102762990B (zh) * | 2009-12-04 | 2014-10-29 | 生命技术公司 | 用于声学流式细胞计量术的装置、系统、方法和计算机可读介质 |
FR2971337B1 (fr) * | 2011-02-04 | 2013-03-01 | Horiba Abx Sas | Dispositif et procede de mesures multiparametriques de microparticules dans un fluide |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2656508A (en) * | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
US3502974A (en) * | 1966-05-23 | 1970-03-24 | Coulter Electronics | Signal modulated apparatus for generating and detecting resistive and reactive changes in a modulated current path for particle classification and analysis |
US3502973A (en) * | 1966-05-23 | 1970-03-24 | Coulter Electronics | Collating apparatus for pairs of electrical pulses produced by particle analyzing apparatus |
US3793587A (en) * | 1971-03-10 | 1974-02-19 | Licentia Gmbh | Particle volume and cross-section measurement |
BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
US3890568A (en) * | 1972-11-06 | 1975-06-17 | Coulter Electronics | Method and apparatus for particle length measurement |
US3941479A (en) * | 1974-09-26 | 1976-03-02 | G. D. Searle & Co. | Use of modulated stimulus to improve detection sensitivity for signals from particles in a flow chamber |
JPS51103482A (es) * | 1975-03-08 | 1976-09-13 | Toa Electric Co Ltd | |
DE2656654C3 (de) * | 1976-12-14 | 1981-02-12 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaftense.V., 3400 Goettingen | Vorrichtung zur Messung des Volumens und bestimmter optischer Eigenschaften von Partikeln |
US4165484A (en) * | 1977-03-23 | 1979-08-21 | Becton, Dickinson And Company | Particle counting apparatus utilizing various fluid resistors to maintain proper pressure differentials |
US4224567A (en) * | 1978-11-03 | 1980-09-23 | The United States Of America As Represented By The United States Department Of Energy | Apparatus for measuring resistance change only in a cell analyzer and method for calibrating it |
-
1979
- 1979-11-23 US US06/096,945 patent/US4298836A/en not_active Expired - Lifetime
-
1980
- 1980-11-20 BR BR8007591A patent/BR8007591A/pt unknown
- 1980-11-20 AU AU64572/80A patent/AU540023B2/en not_active Ceased
- 1980-11-20 FR FR8024666A patent/FR2470377A1/fr active Granted
- 1980-11-20 CA CA000365078A patent/CA1151730A/en not_active Expired
- 1980-11-20 ES ES497018A patent/ES497018A0/es active Granted
- 1980-11-20 DE DE19803043814 patent/DE3043814A1/de not_active Withdrawn
- 1980-11-20 JP JP16272280A patent/JPS5686336A/ja active Granted
- 1980-11-20 CH CH858780A patent/CH639767A5/fr not_active IP Right Cessation
- 1980-11-20 NL NL8006326A patent/NL8006326A/nl not_active Application Discontinuation
- 1980-11-20 GB GB8037247A patent/GB2064133B/en not_active Expired
- 1980-11-20 IT IT50207/80A patent/IT1148275B/it active
- 1980-11-20 SE SE8008148A patent/SE8008148L/ unknown
Also Published As
Publication number | Publication date |
---|---|
IT8050207A0 (it) | 1980-11-20 |
BR8007591A (pt) | 1981-06-02 |
JPS5686336A (en) | 1981-07-14 |
JPH0225133B2 (es) | 1990-05-31 |
IT1148275B (it) | 1986-11-26 |
AU540023B2 (en) | 1984-10-25 |
US4298836A (en) | 1981-11-03 |
DE3043814A1 (de) | 1981-09-03 |
GB2064133A (en) | 1981-06-10 |
FR2470377B1 (es) | 1985-01-11 |
CA1151730A (en) | 1983-08-09 |
AU6457280A (en) | 1981-05-28 |
NL8006326A (nl) | 1981-06-16 |
SE8008148L (sv) | 1981-05-24 |
FR2470377A1 (fr) | 1981-05-29 |
ES497018A0 (es) | 1981-12-01 |
CH639767A5 (fr) | 1983-11-30 |
GB2064133B (en) | 1983-07-27 |
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