ES8200229A1 - Procedimiento de preparacion de arn ribosomales bacterianos - Google Patents
Procedimiento de preparacion de arn ribosomales bacterianosInfo
- Publication number
- ES8200229A1 ES8200229A1 ES498476A ES498476A ES8200229A1 ES 8200229 A1 ES8200229 A1 ES 8200229A1 ES 498476 A ES498476 A ES 498476A ES 498476 A ES498476 A ES 498476A ES 8200229 A1 ES8200229 A1 ES 8200229A1
- Authority
- ES
- Spain
- Prior art keywords
- rna
- preparation
- klebsiella pneumoniae
- immuno
- preparations based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108091032973 (ribonucleotides)n+m Proteins 0.000 title abstract 5
- 238000002360 preparation method Methods 0.000 title abstract 4
- 241000588747 Klebsiella pneumoniae Species 0.000 title abstract 2
- 230000003308 immunostimulating effect Effects 0.000 title abstract 2
- 108020004418 ribosomal RNA Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000001556 precipitation Methods 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 206010024229 Leprosy Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 abstract 1
- 241000607715 Serratia marcescens Species 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002797 proteolythic effect Effects 0.000 abstract 1
- 210000003705 ribosome Anatomy 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7931442A FR2471785A1 (fr) | 1979-12-21 | 1979-12-21 | Preparations immunostimulantes a base d'arn ribosomaux et procede de preparation des arn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES498476A0 ES498476A0 (es) | 1981-11-16 |
| ES8200229A1 true ES8200229A1 (es) | 1981-11-16 |
Family
ID=9233074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498476A Expired ES8200229A1 (es) | 1979-12-21 | 1980-12-19 | Procedimiento de preparacion de arn ribosomales bacterianos |
Country Status (11)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5927833A (ja) * | 1982-08-06 | 1984-02-14 | Advance Res & Dev Co Ltd | コレステロール乃至トリグリセリド低下剤 |
| JPS61151128A (ja) * | 1984-12-24 | 1986-07-09 | Advance Res & Dev Co Ltd | コレステロ−ル低下活性ｒｎａ画分 |
| US4971801A (en) * | 1986-06-09 | 1990-11-20 | Cell Technology, Inc. | Biologic response modifier |
| GB2216416B (en) * | 1988-03-11 | 1992-06-24 | Sandoz Ltd | Nucleobase source for the stimulation of the immune system |
| EP0367724B1 (en) * | 1988-10-31 | 1993-02-10 | Sandoz Nutrition Ltd. | Improvements in or relating to organic compounds |
| US4997932A (en) * | 1989-11-13 | 1991-03-05 | Boehringer Mannheim Corporation | Method and kit for purifying nucleic acids |
| FR2674755B1 (fr) * | 1991-04-05 | 1995-02-03 | Thorel Jean Noel | Nouvelles compositions medicamenteuses immunostimulatrices. |
| FR2703252B1 (fr) * | 1993-03-31 | 1996-09-06 | Fernand Narbey Torossian | Complexe immunomodulateur anti SIDA. |
| LT4475B (lt) * | 1997-02-28 | 1999-02-25 | Virmantas Stunžėnas | Informacinės ribonukleino rūgšties panaudojimas vaistinėse medžiagose, skirtose padidinti šios ribonukleino rūgšties koduojamo baltymo kiekį paciento ląstelėse |
| FR2790960B1 (fr) * | 1999-03-15 | 2002-10-31 | Pf Medicament | Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant |
| AU2011244863B2 (en) * | 2006-08-08 | 2013-03-21 | Rheinische Friedrich-Wilhelms-Universitat Bonn | Structure and use of 5' phosphate oligonucleotides |
| EP2056845B1 (en) | 2006-08-08 | 2017-10-11 | Rheinische Friedrich-Wilhelms-Universität Bonn | Structure and use of 5' phosphate oligonucleotides |
| EP2338499A1 (en) * | 2006-10-10 | 2011-06-29 | Gunther Hartmann | 5' triphosphate oligonucleotide induces anti-viral response |
| WO2009141146A1 (en) | 2008-05-21 | 2009-11-26 | Gunther Hartmann | 5' triphosphate oligonucleotide with blunt end and uses thereof |
| EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
| WO2013012875A2 (en) | 2011-07-18 | 2013-01-24 | Mount Sinai School Of Medicine | Bacterial rnas as vaccine adjuvants |
| EP2712870A1 (en) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Novel RIG-I ligands and methods for producing them |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6513M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-07-12 | 1968-12-02 | ||
| FR2253499B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
| FR2305990A1 (fr) * | 1975-04-02 | 1976-10-29 | Fabre Sa Pierre | Preparation de vaccins a base d'acides nucleiques arn associes a des polysaccharides extraits de germes microbiens |
| FR2360314A2 (fr) * | 1976-08-06 | 1978-03-03 | Fabre Sa Pierre | Nouveaux vaccins perfectionnes a base de fractions ribosomales |
| FR2374911A1 (fr) * | 1976-12-21 | 1978-07-21 | Fabre Sa Pierre | Adjuvants d'immunite non specifique |
| FR2388563A1 (fr) | 1977-04-29 | 1978-11-24 | Fabre Sa Pierre | Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires |
-
1979
- 1979-12-21 FR FR7931442A patent/FR2471785A1/fr active Granted
-
1980
- 1980-12-17 CA CA000366967A patent/CA1181703A/en not_active Expired
- 1980-12-19 US US06/293,639 patent/US4389396A/en not_active Expired - Lifetime
- 1980-12-19 AU AU65588/80A patent/AU538896B2/en not_active Expired
- 1980-12-19 ES ES498476A patent/ES8200229A1/es not_active Expired
- 1980-12-19 WO PCT/FR1980/000186 patent/WO1984000688A1/fr unknown
- 1980-12-19 EP EP80401835A patent/EP0031285B1/fr not_active Expired
- 1980-12-19 DE DE8080401835T patent/DE3066115D1/de not_active Expired
- 1980-12-19 AT AT80401835T patent/ATE5797T1/de not_active IP Right Cessation
- 1980-12-22 ZA ZA00807985A patent/ZA807985B/xx unknown
- 1980-12-22 JP JP18177580A patent/JPS56123918A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2471785B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-11-05 |
| AU6558880A (en) | 1981-06-25 |
| ES498476A0 (es) | 1981-11-16 |
| FR2471785A1 (fr) | 1981-06-26 |
| DE3066115D1 (en) | 1984-02-16 |
| ZA807985B (en) | 1982-01-27 |
| EP0031285A3 (en) | 1981-07-15 |
| US4389396A (en) | 1983-06-21 |
| ATE5797T1 (de) | 1984-01-15 |
| WO1984000688A1 (fr) | 1984-03-01 |
| EP0031285A2 (fr) | 1981-07-01 |
| EP0031285B1 (fr) | 1984-01-11 |
| CA1181703A (en) | 1985-01-29 |
| JPS56123918A (en) | 1981-09-29 |
| AU538896B2 (en) | 1984-08-30 |
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