DE3066115D1 - Immuno-stimulating preparations based on ribosomal rna of klebsiella pneumoniae and process for the preparation of these rna - Google Patents

Immuno-stimulating preparations based on ribosomal rna of klebsiella pneumoniae and process for the preparation of these rna

Info

Publication number
DE3066115D1
DE3066115D1 DE8080401835T DE3066115T DE3066115D1 DE 3066115 D1 DE3066115 D1 DE 3066115D1 DE 8080401835 T DE8080401835 T DE 8080401835T DE 3066115 T DE3066115 T DE 3066115T DE 3066115 D1 DE3066115 D1 DE 3066115D1
Authority
DE
Germany
Prior art keywords
rna
klebsiella pneumoniae
preparation
immuno
preparations based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080401835T
Other languages
English (en)
Inventor
D Hinterland Lucien Doussourd
Gerard Normier
Anne-Marie Pinel
Jacques Durand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Application granted granted Critical
Publication of DE3066115D1 publication Critical patent/DE3066115D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
DE8080401835T 1979-12-21 1980-12-19 Immuno-stimulating preparations based on ribosomal rna of klebsiella pneumoniae and process for the preparation of these rna Expired DE3066115D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7931442A FR2471785A1 (fr) 1979-12-21 1979-12-21 Preparations immunostimulantes a base d'arn ribosomaux et procede de preparation des arn

Publications (1)

Publication Number Publication Date
DE3066115D1 true DE3066115D1 (en) 1984-02-16

Family

ID=9233074

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080401835T Expired DE3066115D1 (en) 1979-12-21 1980-12-19 Immuno-stimulating preparations based on ribosomal rna of klebsiella pneumoniae and process for the preparation of these rna

Country Status (11)

Country Link
US (1) US4389396A (de)
EP (1) EP0031285B1 (de)
JP (1) JPS56123918A (de)
AT (1) ATE5797T1 (de)
AU (1) AU538896B2 (de)
CA (1) CA1181703A (de)
DE (1) DE3066115D1 (de)
ES (1) ES498476A0 (de)
FR (1) FR2471785A1 (de)
WO (1) WO1984000688A1 (de)
ZA (1) ZA807985B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5927833A (ja) * 1982-08-06 1984-02-14 Advance Res & Dev Co Ltd コレステロール乃至トリグリセリド低下剤
JPS61151128A (ja) * 1984-12-24 1986-07-09 Advance Res & Dev Co Ltd コレステロ−ル低下活性ｒｎａ画分
US4971801A (en) * 1986-06-09 1990-11-20 Cell Technology, Inc. Biologic response modifier
GB2216416B (en) * 1988-03-11 1992-06-24 Sandoz Ltd Nucleobase source for the stimulation of the immune system
EP0367724B1 (de) * 1988-10-31 1993-02-10 Sandoz Nutrition Ltd. Organische Verbindungen
US4997932A (en) * 1989-11-13 1991-03-05 Boehringer Mannheim Corporation Method and kit for purifying nucleic acids
FR2674755B1 (fr) * 1991-04-05 1995-02-03 Thorel Jean Noel Nouvelles compositions medicamenteuses immunostimulatrices.
FR2703252B1 (fr) * 1993-03-31 1996-09-06 Fernand Narbey Torossian Complexe immunomodulateur anti SIDA.
LT4475B (lt) * 1997-02-28 1999-02-25 Virmantas Stunžėnas Informacinės ribonukleino rūgšties panaudojimas vaistinėse medžiagose, skirtose padidinti šios ribonukleino rūgšties koduojamo baltymo kiekį paciento ląstelėse
FR2790960B1 (fr) * 1999-03-15 2002-10-31 Pf Medicament Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant
AU2011244863B2 (en) * 2006-08-08 2013-03-21 Rheinische Friedrich-Wilhelms-Universitat Bonn Structure and use of 5' phosphate oligonucleotides
EP4082551A1 (de) 2006-08-08 2022-11-02 Rheinische Friedrich-Wilhelms-Universität Bonn Struktur und verwendung von 5'-phosphat-oligonukleotiden
EP2338499A1 (de) * 2006-10-10 2011-06-29 Gunther Hartmann 5' Triphosphat -oligonukleotid induziert eine antivirale Reaktion
EP2297323A1 (de) 2008-05-21 2011-03-23 Hartmann, Gunther 5 -triphosphat-oligonukleotid mit stumpfem ende und verwendugen davon
EP2508530A1 (de) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Reinigung von triphosphorylierten Oligonucleotiden mit Einfang-Tags
WO2013012875A2 (en) 2011-07-18 2013-01-24 Mount Sinai School Of Medicine Bacterial rnas as vaccine adjuvants
EP2712870A1 (de) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Neuartige RIG-I-Liganden und Herstellungsverfahren dafür

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6513M (de) * 1967-07-12 1968-12-02
FR2253499B1 (de) * 1973-12-10 1977-11-04 Fabre Sa Pierre
FR2305990A1 (fr) * 1975-04-02 1976-10-29 Fabre Sa Pierre Preparation de vaccins a base d'acides nucleiques arn associes a des polysaccharides extraits de germes microbiens
FR2360314A2 (fr) * 1976-08-06 1978-03-03 Fabre Sa Pierre Nouveaux vaccins perfectionnes a base de fractions ribosomales
FR2374911A1 (fr) * 1976-12-21 1978-07-21 Fabre Sa Pierre Adjuvants d'immunite non specifique
FR2388563A1 (fr) * 1977-04-29 1978-11-24 Fabre Sa Pierre Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires

Also Published As

Publication number Publication date
FR2471785B1 (de) 1982-11-05
ZA807985B (en) 1982-01-27
EP0031285A3 (en) 1981-07-15
ES8200229A1 (es) 1981-11-16
FR2471785A1 (fr) 1981-06-26
US4389396A (en) 1983-06-21
CA1181703A (en) 1985-01-29
AU6558880A (en) 1981-06-25
EP0031285A2 (de) 1981-07-01
EP0031285B1 (de) 1984-01-11
ES498476A0 (es) 1981-11-16
AU538896B2 (en) 1984-08-30
JPS56123918A (en) 1981-09-29
ATE5797T1 (de) 1984-01-15
WO1984000688A1 (fr) 1984-03-01

Similar Documents

Publication Publication Date Title
DE3066115D1 (en) Immuno-stimulating preparations based on ribosomal rna of klebsiella pneumoniae and process for the preparation of these rna
PL241175A1 (en) Process for preparing novel quaternary 6,11-dihydro-dibenzo-/b,e/-thiepine-11-n-alkylnorskopinethers
GR3001544T3 (en) Process for combating fungicides
IL130931A0 (en) Small molecules useful in the treatment of inflammatory disease
ES500567A0 (es) Procedimiento de preparar complejos vacunantes por reaccion de arn ribonosales y de antigenos especificos.
GR78442B (de)
AU1808488A (en) Compounds for the treatment of alzheimer's disease
ES470181A1 (es) Procedimiento de obtencion de materiales de poliuretano
FR2444464B1 (de)
ES8801243A1 (es) Procedimiento para la obtencion de medicamentos que contienen 1-heteroaril-4--aril-pirazolin-5-onas.
PL275056A1 (en) Method of obtaining derivatives of 4-aminopyridine
HUT39152A (en) Process for preparing 1-substituted tetraline-derivatives
NL188284C (nl) Werkwijze voor de bereiding van alfa, beta-onverzadigde n-gesubstitueerde carbonzuuramiden.
DE2964602D1 (en) 4,6-di-0-(aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them
ES483661A1 (es) Procedimiento para la obtencion de derivados de 1,4-dihidro-piridina sila-sustituidos
CA2109977A1 (en) Giardia vaccines
IL79260A0 (en) Effector cells and compositions containing them for treatment of cancer and nonmalignant tumors
AU539847B2 (en) 3,4,5-trihydroxypiperidine compounds
EP0147707A3 (en) 1,7-diphenyl-3-methylaza-7-cyano-8-methylnonane useful in combating diseases
GR73033B (de)
PT84384A (en) Process for preparing isohexide nucleosides useful as medicaments
JPS55390A (en) Synthesis of anthracycline
IT8720288A0 (it) Forno per il trattamento di articoli di pelletteria o simili,quali le calzature, applicabile a catene continue di lavorazione.
MX9802809A (es) Ureasa para el tratamiento de infecciones de helicobacter pylori.
GB2126893B (en) Obtaining tf-500 substance from fusobacterium

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: PIERRE FABRE S.A., BOULOGNE, FR