ATE5797T1 - Immunostimulierende zusammensetzungen auf der basis von ribosomen rns von klebsiella pneumoniae und verfahren zur herstellung dieser rns. - Google Patents

Immunostimulierende zusammensetzungen auf der basis von ribosomen rns von klebsiella pneumoniae und verfahren zur herstellung dieser rns.

Info

Publication number
ATE5797T1
ATE5797T1 AT80401835T AT80401835T ATE5797T1 AT E5797 T1 ATE5797 T1 AT E5797T1 AT 80401835 T AT80401835 T AT 80401835T AT 80401835 T AT80401835 T AT 80401835T AT E5797 T1 ATE5797 T1 AT E5797T1
Authority
AT
Austria
Prior art keywords
rna
klebsiella pneumoniae
production
methods
ribosomic
Prior art date
Application number
AT80401835T
Other languages
English (en)
Inventor
Lucien Dr. Doussourd D'hinterland
Gerard Normier
Anne-Marie Pinel
Jacques Durand
Original Assignee
Pierre Fabre S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre S.A. filed Critical Pierre Fabre S.A.
Application granted granted Critical
Publication of ATE5797T1 publication Critical patent/ATE5797T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
AT80401835T 1979-12-21 1980-12-19 Immunostimulierende zusammensetzungen auf der basis von ribosomen rns von klebsiella pneumoniae und verfahren zur herstellung dieser rns. ATE5797T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7931442A FR2471785A1 (fr) 1979-12-21 1979-12-21 Preparations immunostimulantes a base d'arn ribosomaux et procede de preparation des arn
EP80401835A EP0031285B1 (de) 1979-12-21 1980-12-19 Immunostimulierende Zusammensetzungen auf der Basis von Ribosomen RNS von Klebsiella pneumoniae und Verfahren zur Herstellung dieser RNS

Publications (1)

Publication Number Publication Date
ATE5797T1 true ATE5797T1 (de) 1984-01-15

Family

ID=9233074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80401835T ATE5797T1 (de) 1979-12-21 1980-12-19 Immunostimulierende zusammensetzungen auf der basis von ribosomen rns von klebsiella pneumoniae und verfahren zur herstellung dieser rns.

Country Status (11)

Country Link
US (1) US4389396A (de)
EP (1) EP0031285B1 (de)
JP (1) JPS56123918A (de)
AT (1) ATE5797T1 (de)
AU (1) AU538896B2 (de)
CA (1) CA1181703A (de)
DE (1) DE3066115D1 (de)
ES (1) ES498476A0 (de)
FR (1) FR2471785A1 (de)
WO (1) WO1984000688A1 (de)
ZA (1) ZA807985B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5927833A (ja) * 1982-08-06 1984-02-14 Advance Res & Dev Co Ltd コレステロール乃至トリグリセリド低下剤
JPS61151128A (ja) * 1984-12-24 1986-07-09 Advance Res & Dev Co Ltd コレステロ−ル低下活性ｒｎａ画分
US4971801A (en) * 1986-06-09 1990-11-20 Cell Technology, Inc. Biologic response modifier
GB2216416B (en) * 1988-03-11 1992-06-24 Sandoz Ltd Nucleobase source for the stimulation of the immune system
EP0367724B1 (de) * 1988-10-31 1993-02-10 Sandoz Nutrition Ltd. Organische Verbindungen
US4997932A (en) * 1989-11-13 1991-03-05 Boehringer Mannheim Corporation Method and kit for purifying nucleic acids
FR2674755B1 (fr) * 1991-04-05 1995-02-03 Thorel Jean Noel Nouvelles compositions medicamenteuses immunostimulatrices.
FR2703252B1 (fr) * 1993-03-31 1996-09-06 Fernand Narbey Torossian Complexe immunomodulateur anti SIDA.
LT4475B (lt) * 1997-02-28 1999-02-25 Virmantas Stunžėnas Informacinės ribonukleino rūgšties panaudojimas vaistinėse medžiagose, skirtose padidinti šios ribonukleino rūgšties koduojamo baltymo kiekį paciento ląstelėse
FR2790960B1 (fr) * 1999-03-15 2002-10-31 Pf Medicament Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant
AU2011244863B2 (en) * 2006-08-08 2013-03-21 Rheinische Friedrich-Wilhelms-Universitat Bonn Structure and use of 5' phosphate oligonucleotides
EP4082551A1 (de) 2006-08-08 2022-11-02 Rheinische Friedrich-Wilhelms-Universität Bonn Struktur und verwendung von 5'-phosphat-oligonukleotiden
EP2338499A1 (de) * 2006-10-10 2011-06-29 Gunther Hartmann 5' Triphosphat -oligonukleotid induziert eine antivirale Reaktion
EP2297323A1 (de) 2008-05-21 2011-03-23 Hartmann, Gunther 5 -triphosphat-oligonukleotid mit stumpfem ende und verwendugen davon
EP2508530A1 (de) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Reinigung von triphosphorylierten Oligonucleotiden mit Einfang-Tags
WO2013012875A2 (en) 2011-07-18 2013-01-24 Mount Sinai School Of Medicine Bacterial rnas as vaccine adjuvants
EP2712870A1 (de) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Neuartige RIG-I-Liganden und Herstellungsverfahren dafür

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6513M (de) * 1967-07-12 1968-12-02
FR2253499B1 (de) * 1973-12-10 1977-11-04 Fabre Sa Pierre
FR2305990A1 (fr) * 1975-04-02 1976-10-29 Fabre Sa Pierre Preparation de vaccins a base d'acides nucleiques arn associes a des polysaccharides extraits de germes microbiens
FR2360314A2 (fr) * 1976-08-06 1978-03-03 Fabre Sa Pierre Nouveaux vaccins perfectionnes a base de fractions ribosomales
FR2374911A1 (fr) * 1976-12-21 1978-07-21 Fabre Sa Pierre Adjuvants d'immunite non specifique
FR2388563A1 (fr) * 1977-04-29 1978-11-24 Fabre Sa Pierre Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires

Also Published As

Publication number Publication date
FR2471785B1 (de) 1982-11-05
DE3066115D1 (en) 1984-02-16
ZA807985B (en) 1982-01-27
EP0031285A3 (en) 1981-07-15
ES8200229A1 (es) 1981-11-16
FR2471785A1 (fr) 1981-06-26
US4389396A (en) 1983-06-21
CA1181703A (en) 1985-01-29
AU6558880A (en) 1981-06-25
EP0031285A2 (de) 1981-07-01
EP0031285B1 (de) 1984-01-11
ES498476A0 (es) 1981-11-16
AU538896B2 (en) 1984-08-30
JPS56123918A (en) 1981-09-29
WO1984000688A1 (fr) 1984-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time