ES8200093A1 - Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas. - Google Patents

Un procedimiento para la preparacion de 1-(2-(alquil y ari sulfonil)-2- propenil y propil) piperidinas.

Info

Publication number
ES8200093A1
ES8200093A1 ES495422A ES495422A ES8200093A1 ES 8200093 A1 ES8200093 A1 ES 8200093A1 ES 495422 A ES495422 A ES 495422A ES 495422 A ES495422 A ES 495422A ES 8200093 A1 ES8200093 A1 ES 8200093A1
Authority
ES
Spain
Prior art keywords
arylsulfonyl
propenyl
propyl
alkyl
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495422A
Other languages
English (en)
Other versions
ES495422A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8200093A1 publication Critical patent/ES8200093A1/es
Publication of ES495422A0 publication Critical patent/ES495422A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-(2-(ALQUIL Y ARILSULFONIL)-2-PROPENIL Y PROPIL)PIPERIDINAS DE FORMULA (I), U SUS SALES DE ADICION DE ACIDO, DONDE R3, R4 Y M PUEDEN SER DIFERENTES RADICALES Y A ES UN RADICAL DE FORMULA (II), DONDE R, R1 Y R2 SON DIFERENTES RADICALES. UN COMPUESTO DE FORMULA (III) SE HACE REACCIONAR CON OTRO DE FORMULA RSO2CH2COOH. EL COMPUESTO OBTENIDO SE HACE REACCIONAR CON EL REPRESENTADO POR LA FORMULA (IV) PARA OBTENER EL COMPUESTO DESEADO. DE APLICACION EN LA PROTECCION DE PRODUCTOS INDUSTRIALES CONTRA LA ACCION DETERIORANTE DE BASTERIAS Y HONGOS Y EN COMPOSICIONES ANTIINFLAMATORIAS.
ES495422A 1979-09-27 1980-09-26 Un procedimiento para la preparacion de 1-Ÿ2-(alquil y ari sulfonil)-2- propenil y propilŸ piperidinas. Granted ES495422A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/079,281 US4244963A (en) 1979-09-27 1979-09-27 1-[2-(Alkyl and arylsulfonyl)-2-propenyl and propyl] substituted piperidines useful as antimicrobial and antiinflammatory agents

Publications (2)

Publication Number Publication Date
ES8200093A1 true ES8200093A1 (es) 1981-10-16
ES495422A0 ES495422A0 (es) 1981-10-16

Family

ID=22149549

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495422A Granted ES495422A0 (es) 1979-09-27 1980-09-26 Un procedimiento para la preparacion de 1-Ÿ2-(alquil y ari sulfonil)-2- propenil y propilŸ piperidinas.

Country Status (7)

Country Link
US (1) US4244963A (es)
EP (1) EP0027895A1 (es)
JP (1) JPS5657765A (es)
DK (1) DK407080A (es)
ES (1) ES495422A0 (es)
GR (1) GR70064B (es)
PT (1) PT71828B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668692A (en) * 1984-05-07 1987-05-26 Noorlander Daniel O Dry powdered germicide and healing compositions
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US5179095A (en) * 1986-02-26 1993-01-12 Eisai Co., Ltd. Piperidine derivative and pharmaceutical composition containing the same
US5348964A (en) * 1990-07-25 1994-09-20 Merrell Dow Pharmaceuticals Inc. Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
ZA915659B (en) * 1990-07-25 1992-05-27 Merrell Dow Pharma Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487469A (en) * 1965-02-26 1969-12-30 Ciba Geigy Corp 1,2-diaryl-3-(aminomethyl)-3-buten-2-ols and their acyl derivatives
US4145426A (en) * 1977-07-18 1979-03-20 Merck & Co., Inc. Anti-microbial piperidino butan-2-ones

Also Published As

Publication number Publication date
GR70064B (es) 1982-07-26
JPS5657765A (en) 1981-05-20
US4244963A (en) 1981-01-13
PT71828A (en) 1980-10-01
EP0027895A1 (en) 1981-05-06
ES495422A0 (es) 1981-10-16
DK407080A (da) 1981-03-28
PT71828B (en) 1982-03-26

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