ES8105746A1 - Procedimiento para producir el compuesto (n-fosfonacetil-l- aspartato) (1,2-diaminociclohexano) platino (ii). - Google Patents

Procedimiento para producir el compuesto (n-fosfonacetil-l- aspartato) (1,2-diaminociclohexano) platino (ii).

Info

Publication number
ES8105746A1
ES8105746A1 ES493474A ES493474A ES8105746A1 ES 8105746 A1 ES8105746 A1 ES 8105746A1 ES 493474 A ES493474 A ES 493474A ES 493474 A ES493474 A ES 493474A ES 8105746 A1 ES8105746 A1 ES 8105746A1
Authority
ES
Spain
Prior art keywords
platinum
phosphonacetil
compound
procedure
diaminociclohexane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493474A
Other languages
English (en)
Spanish (es)
Other versions
ES493474A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Commerce
Government of the United States of America
Original Assignee
United States Department of Commerce
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Commerce, Government of the United States of America filed Critical United States Department of Commerce
Publication of ES493474A0 publication Critical patent/ES493474A0/es
Publication of ES8105746A1 publication Critical patent/ES8105746A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES493474A 1979-07-17 1980-07-17 Procedimiento para producir el compuesto (n-fosfonacetil-l- aspartato) (1,2-diaminociclohexano) platino (ii). Expired ES8105746A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5828779A 1979-07-17 1979-07-17
US06/155,531 US4284579A (en) 1979-07-17 1980-06-09 (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt

Publications (2)

Publication Number Publication Date
ES493474A0 ES493474A0 (es) 1981-06-16
ES8105746A1 true ES8105746A1 (es) 1981-06-16

Family

ID=26737454

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493474A Expired ES8105746A1 (es) 1979-07-17 1980-07-17 Procedimiento para producir el compuesto (n-fosfonacetil-l- aspartato) (1,2-diaminociclohexano) platino (ii).

Country Status (8)

Country Link
US (1) US4284579A (enExample)
EP (1) EP0026813B1 (enExample)
JP (1) JPS56500849A (enExample)
CA (1) CA1151663A (enExample)
DE (1) DE3069356D1 (enExample)
ES (1) ES8105746A1 (enExample)
IL (1) IL60575A (enExample)
WO (1) WO1981000256A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75598B (enExample) * 1980-04-29 1984-08-01 Sanofi Sa
DE3475782D1 (en) * 1983-06-20 1989-02-02 Research Corp Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US4670458A (en) * 1986-01-31 1987-06-02 American Cyanamid Company Hydroxylated 1,2-diaminocyclohexane platinum complexes
US4882447A (en) * 1987-02-20 1989-11-21 Tanabe Seiyaku Co., Ltd. Novel organic platinum complex and process for the preparation thereof
IL85595A0 (en) * 1987-03-06 1988-08-31 Tanabe Seiyaku Co Organic platinum complex and its preparation
US4895935A (en) * 1987-07-17 1990-01-23 Georgetown University Platinum pharmaceuticals
CA1330793C (en) * 1987-07-17 1994-07-19 Abdolhossen Talebian Platinum pharmaceuticals
US4956459A (en) * 1987-07-17 1990-09-11 Georgetown University Platinum compounds suitable for use as pharmaceuticals
US4895936A (en) * 1987-07-17 1990-01-23 Georgetown University Platinum pharmaceuticals
US4946954A (en) * 1989-01-17 1990-08-07 Georgetown University Platinum pharmaceutical agents
US5657470A (en) * 1994-11-09 1997-08-12 Ybm Technologies, Inc. Personal computer hard disk protection system
KR0164460B1 (ko) * 1995-10-02 1999-03-20 김은영 고분자 백금 착화합물, 그의 제조방법 및 그를 유효성분으로 하는 항암제
JP2002522392A (ja) * 1998-08-05 2002-07-23 アベンテイス・フアルマ・ソシエテ・アノニム 低下された消化管毒性を有するカンプトテシン誘導体の使用
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
KR100363394B1 (ko) * 2000-08-21 2002-12-05 한국과학기술연구원 온도감응성을 갖는 포스파젠삼량체-백금착물 복합체, 그의제조방법 및 그를 함유하는 항암제 조성물
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
KR20040074857A (ko) * 2003-02-19 2004-08-26 학교법인 이화학당 Ｎ-치환 아미노디카복실산의 백금(ⅱ) 착물 및 그 제조방법
WO2006091790A1 (en) * 2005-02-23 2006-08-31 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588505A5 (enExample) * 1972-06-08 1977-06-15 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
AU520966B2 (en) * 1977-11-14 1982-03-11 Starks Associates, Inc. N-phosphonoacetyl-l-aspartic and derivatives
GB2019397B (en) * 1978-04-20 1982-10-27 Johnson Matthey Co Ltd Pt 2 and 4 complexes with amino-acids

Also Published As

Publication number Publication date
EP0026813B1 (en) 1984-10-03
ES493474A0 (es) 1981-06-16
CA1151663A (en) 1983-08-09
US4284579A (en) 1981-08-18
EP0026813A2 (en) 1981-04-15
WO1981000256A1 (en) 1981-02-05
EP0026813A3 (en) 1982-02-03
IL60575A (en) 1983-10-31
DE3069356D1 (en) 1984-11-08
JPS56500849A (enExample) 1981-06-25

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