ES8105150A1 - Procedimiento para preparar una vacuna inactivada de reo-vi-rus - Google Patents

Procedimiento para preparar una vacuna inactivada de reo-vi-rus

Info

Publication number
ES8105150A1
ES8105150A1 ES494598A ES494598A ES8105150A1 ES 8105150 A1 ES8105150 A1 ES 8105150A1 ES 494598 A ES494598 A ES 494598A ES 494598 A ES494598 A ES 494598A ES 8105150 A1 ES8105150 A1 ES 8105150A1
Authority
ES
Spain
Prior art keywords
reo
virus
vaccine
preparation
followed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494598A
Other languages
English (en)
Other versions
ES494598A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL7812359A external-priority patent/NL7812359A/nl
Priority claimed from NL7903299A external-priority patent/NL7903299A/nl
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of ES494598A0 publication Critical patent/ES494598A0/es
Publication of ES8105150A1 publication Critical patent/ES8105150A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UNA VACUNA INACTIVADA DE REO-VIRUS. CONSTA DE LAS SIGUIENTES ETAPAS: 1. PREPARAR UN LIQUIDO CONTENIENDO REO-VIRUS, CULTIVANDO UN REO-VIRUS TAL COMO LA CEPA LZ671 EN HUEVO DE GALLINA INCUBADO O EN UN CULTIVO DE CELULAS FIBROBLASTICAS DE EMBRION DE POLLO SPF EN FORMA DE UN CULTIVO DE FRASCO DE ROTACION DE MONOCAPA O UN CULTIVO DE CELULAS UNIDAS A PORTADORES INERTES SOLIDOS. 2. RECOGER EL VIRUS CULTIVADO EN UN LIQUIDO DE VALORACION APROPIADA. 3. INACTIVARLO. 4. SUSPENDERLO EN UNA SOLUCION TAMPONADA. 5. HOMOGENEIZARLO. EL CULTIVO CELULAR SE INOCULA CON UNA SUSPENSION DE REO-VIRUS QUE TIENE UNA ACTIVIDAD DE 2X10 ELEVADO A 6 A 10 ELEVADO A 8 TCLD50/FRASCO DE CULTIVO DE ROTACION. PRODUCCION DE VACUNAS.
ES494598A 1978-12-20 1980-08-29 Procedimiento para preparar una vacuna inactivada de reo-vi-rus Expired ES8105150A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7812359A NL7812359A (nl) 1978-12-20 1978-12-20 Vaccins tegen door reo virus veroorzaakte ziektever- schijnselen en werkwijze voor het bereiden van deze vaccins.
NL7903299A NL7903299A (nl) 1979-04-26 1979-04-26 Vaccins tegen door reo virus veroorzaakte ziekte- verschijnselen en werkwijze voor het bereiden van deze vaccins.

Publications (2)

Publication Number Publication Date
ES494598A0 ES494598A0 (es) 1981-05-16
ES8105150A1 true ES8105150A1 (es) 1981-05-16

Family

ID=26645475

Family Applications (2)

Application Number Title Priority Date Filing Date
ES487062A Granted ES487062A0 (es) 1978-12-20 1979-12-19 Procedimiento para preparar una vacuna inactivada de reo-vi-rus
ES494598A Expired ES8105150A1 (es) 1978-12-20 1980-08-29 Procedimiento para preparar una vacuna inactivada de reo-vi-rus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES487062A Granted ES487062A0 (es) 1978-12-20 1979-12-19 Procedimiento para preparar una vacuna inactivada de reo-vi-rus

Country Status (10)

Country Link
EP (1) EP0013449B1 (es)
CA (1) CA1136043A (es)
DE (1) DE2966648D1 (es)
DK (1) DK547279A (es)
ES (2) ES487062A0 (es)
FR (1) FR2444467A1 (es)
GR (1) GR74012B (es)
IE (1) IE48722B1 (es)
LU (1) LU82018A1 (es)
PT (1) PT70556A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
HU197517B (en) * 1984-07-30 1989-04-28 Laszlo Csatary Process for production of terapeutical composition applicable against virus infection
US5525342A (en) * 1994-05-20 1996-06-11 Akzo Nobel, N.V. Reovirus strain 2177 and vaccine containing same
US6136307A (en) 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
EP2474714B1 (en) 2010-12-23 2013-04-03 C.R.F. Società Consortile per Azioni Internal combustion engine with wall masking the curtain area of the intake valves

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4823893B1 (es) * 1970-12-29 1973-07-17
NL7408579A (en) * 1974-06-26 1975-12-30 Philips Nv Vaccine against respiratory infections esp in horses - contg an adsorbed, killed suspension of reovirus in water

Also Published As

Publication number Publication date
ES8107026A1 (es) 1980-12-16
IE792495L (en) 1980-06-20
LU82018A1 (fr) 1981-07-23
ES494598A0 (es) 1981-05-16
FR2444467A1 (fr) 1980-07-18
IE48722B1 (en) 1985-05-01
DK547279A (da) 1980-06-21
DE2966648D1 (en) 1984-03-15
EP0013449A1 (en) 1980-07-23
EP0013449B1 (en) 1984-02-08
CA1136043A (en) 1982-11-23
PT70556A (en) 1980-01-01
ES487062A0 (es) 1980-12-16
FR2444467B1 (es) 1984-11-02
GR74012B (es) 1984-06-06

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