ES8104799A1 - Bis-(p-(1-etoxi-etoxi)fenil)-2-piridilmetano - Google Patents
Bis-(p-(1-etoxi-etoxi)fenil)-2-piridilmetanoInfo
- Publication number
- ES8104799A1 ES8104799A1 ES492397A ES492397A ES8104799A1 ES 8104799 A1 ES8104799 A1 ES 8104799A1 ES 492397 A ES492397 A ES 492397A ES 492397 A ES492397 A ES 492397A ES 8104799 A1 ES8104799 A1 ES 8104799A1
- Authority
- ES
- Spain
- Prior art keywords
- contain
- pharmaceutical compositions
- preparation
- new compound
- laxative activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000002475 laxative effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- FJKIXWOMBXYWOQ-UHFFFAOYSA-N ethenoxyethane Chemical compound CCOC=C FJKIXWOMBXYWOQ-UHFFFAOYSA-N 0.000 abstract 2
- NHSIAYALMFHUEY-UHFFFAOYSA-N 2-[bis[4-(1-ethoxyethoxy)phenyl]methyl]pyridine Chemical compound C(C)OC(C)OC1=CC=C(C=C1)C(C1=NC=CC=C1)C1=CC=C(C=C1)OC(C)OCC NHSIAYALMFHUEY-UHFFFAOYSA-N 0.000 abstract 1
- LJROKJGQSPMTKB-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol Chemical compound C1=CC(O)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(O)C=C1 LJROKJGQSPMTKB-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE BIS-[P-(1-ETOXI-ETOXI) FENIL]-2-PIRIDILMETANO DE FORMULA (I). CONSISTENTE EN OBTENER EL COMPUESTO (I) POR REACCION DEL BIS-(P-HIDROXIFENIL)-2-PIRIDILMETANO CON ETILVINILETER, EN PRESENCIA DE CATALIZADORES ACIDOS. A SU VEZ, EL BIS-(P-HIDROXIFENIL)-2-PIRIDIL-METANO ES FACILMENTE ACCESIBLE, POR EJEMPLO, MEDIANTE HIDROLISIS DE DIACETOXIDERIVADO CORRESPONDIENTE, QUE ES UN PRODUCTO COMERCIAL CONOCIDO. LA REACCION PARA OBTENCION DE (I) SE EFECTUA, DE PREFERENCIA, A UNA TEMPERATURA COMPRENDIDA ENTRE 0 Y 60GC, OPORTUNAMENTE ENTRE 10 Y 30GC. ES APROPIADO OPERAR EN DISOLVENTES INERTES, POR EJEMPLO, EN ETER ETILICO, O E TETRAHIDROFURANO, O EN DIOXANO Y SIMILARES. SE UTILIZA COMO MATERIA ACTIVA PARA LA OBTENCION DE COMPOSICIONES FARMACEUTICAS CON ACTIVIDAD LAXANTE. *FORMULA*
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23571/79A IT1121574B (it) | 1979-06-14 | 1979-06-14 | Nouvo composto ad attivita'lassativa,processo per la sua preparazione e composizioni farmaceutiche che lo contengono |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES492397A0 ES492397A0 (es) | 1981-05-16 |
| ES8104799A1 true ES8104799A1 (es) | 1981-05-16 |
Family
ID=11208226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES492397A Expired ES8104799A1 (es) | 1979-06-14 | 1980-06-13 | Bis-(p-(1-etoxi-etoxi)fenil)-2-piridilmetano |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS568366A (es) |
| AR (1) | AR223223A1 (es) |
| BE (1) | BE883804A (es) |
| CH (1) | CH646692A5 (es) |
| DE (1) | DE3021785A1 (es) |
| ES (1) | ES8104799A1 (es) |
| FR (1) | FR2459232A1 (es) |
| GB (1) | GB2051801B (es) |
| IT (1) | IT1121574B (es) |
| MX (1) | MX5881E (es) |
| NL (1) | NL8003465A (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6222690Y2 (es) * | 1980-10-21 | 1987-06-09 | ||
| JPS5872747A (ja) * | 1981-10-28 | 1983-04-30 | Nissan Motor Co Ltd | パワ−ユニツトのリアマウンテイング装置 |
| IT1167197B (it) * | 1983-07-25 | 1987-05-13 | Bellon Roger Schoum Rbs Pharma | Impiego della fenpiramina quale farmaco antiaggregante piastrinico,vasodilatatore,antitrombotico e antianginoso |
| JPH01283222A (ja) * | 1988-05-10 | 1989-11-14 | Tokai Kapuseru Kk | ピコスルフアートナトリウム軟カプセル剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB730243A (es) * | ||||
| FR75159E (es) * | 1961-09-08 | |||
| US2764590A (en) * | 1952-03-17 | 1956-09-25 | Thomae Gmbh Dr K | Certain 4, 4'-disubstituted-diphenylpyridyl methanes and process |
-
1979
- 1979-06-14 IT IT23571/79A patent/IT1121574B/it active
-
1980
- 1980-06-10 DE DE19803021785 patent/DE3021785A1/de active Granted
- 1980-06-10 GB GB8018930A patent/GB2051801B/en not_active Expired
- 1980-06-12 MX MX808872U patent/MX5881E/es unknown
- 1980-06-13 AR AR281393A patent/AR223223A1/es active
- 1980-06-13 FR FR8013234A patent/FR2459232A1/fr active Granted
- 1980-06-13 BE BE2/58605A patent/BE883804A/nl not_active IP Right Cessation
- 1980-06-13 JP JP8082880A patent/JPS568366A/ja active Granted
- 1980-06-13 CH CH456780A patent/CH646692A5/it not_active IP Right Cessation
- 1980-06-13 NL NL8003465A patent/NL8003465A/nl not_active Application Discontinuation
- 1980-06-13 ES ES492397A patent/ES8104799A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2051801A (en) | 1981-01-21 |
| CH646692A5 (it) | 1984-12-14 |
| ES492397A0 (es) | 1981-05-16 |
| IT7923571A0 (it) | 1979-06-14 |
| JPS5745431B2 (es) | 1982-09-28 |
| GB2051801B (en) | 1983-03-09 |
| BE883804A (nl) | 1980-10-01 |
| FR2459232B1 (es) | 1984-05-18 |
| DE3021785C2 (es) | 1988-04-28 |
| DE3021785A1 (de) | 1980-12-18 |
| AR223223A1 (es) | 1981-07-31 |
| JPS568366A (en) | 1981-01-28 |
| NL8003465A (nl) | 1980-12-16 |
| IT1121574B (it) | 1986-04-02 |
| MX5881E (es) | 1984-08-16 |
| FR2459232A1 (fr) | 1981-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000201 |