ES8104252A1 - Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina - Google Patents

Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina

Info

Publication number
ES8104252A1
ES8104252A1 ES491004A ES491004A ES8104252A1 ES 8104252 A1 ES8104252 A1 ES 8104252A1 ES 491004 A ES491004 A ES 491004A ES 491004 A ES491004 A ES 491004A ES 8104252 A1 ES8104252 A1 ES 8104252A1
Authority
ES
Spain
Prior art keywords
therapeutic use
halogeno
isopropylamino pyrimidine
isopropylamino
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491004A
Other languages
English (en)
Other versions
ES491004A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505180&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8104252(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES8104252A1 publication Critical patent/ES8104252A1/es
Publication of ES491004A0 publication Critical patent/ES491004A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS HALOGENADOS DE ISOPROPILAMINOPIRIDINA DE FORMULA: *FORMULA* DONDE X PUEDE SER UN ATOMO DE FLUOR, CLORO O BROMO. SE OBTIENE HACIENDO REACCIONAR EN PROPORCIONES ESTEQUIOMETRICAS 2-ISOPROPILAMINA-PIRIMIDINA CON N-HALOGENO-SUCCINIMIDA EN PRESENCIA DE ACIDO ACETICO. LA TEMPERATURA DE REACCION ES LA DEL AMBIENTE. ESTOS COMPUESTOS PRESENTAN APLICACION EN EL TRATAMIENTO DE NEUROPATIAS.
ES491004A 1979-05-15 1980-04-29 Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina Granted ES491004A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7916918 1979-05-15

Publications (2)

Publication Number Publication Date
ES8104252A1 true ES8104252A1 (es) 1981-04-01
ES491004A0 ES491004A0 (es) 1981-04-01

Family

ID=10505180

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491004A Granted ES491004A0 (es) 1979-05-15 1980-04-29 Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina

Country Status (30)

Country Link
US (1) US4267181A (es)
JP (1) JPS55151571A (es)
AR (1) AR222872A1 (es)
AT (1) AT375074B (es)
AU (1) AU529581B2 (es)
BE (1) BE882836A (es)
CA (1) CA1132562A (es)
CH (1) CH645103A5 (es)
DE (1) DE3016549A1 (es)
DK (1) DK183980A (es)
EG (1) EG14260A (es)
ES (1) ES491004A0 (es)
FI (1) FI68045C (es)
FR (2) FR2456734A1 (es)
HK (1) HK55483A (es)
IE (1) IE49708B1 (es)
IN (1) IN154370B (es)
IT (1) IT1148798B (es)
LU (1) LU82379A1 (es)
MA (1) MA18825A1 (es)
MX (1) MX6295E (es)
MY (1) MY8400201A (es)
NL (1) NL8002421A (es)
NO (1) NO154057C (es)
NZ (1) NZ193533A (es)
OA (1) OA06526A (es)
PT (1) PT71162A (es)
SE (1) SE435177B (es)
SG (1) SG22483G (es)
ZA (1) ZA802375B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (fr) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4868161A (en) * 1984-06-29 1989-09-19 City Of Hope Method for promoting nerve regeneration
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2436360A (en) * 1948-02-17 Preparation of z-amino-s-chloro
US2609372A (en) * 1950-05-05 1952-09-02 Sharp & Dohme Inc Halogenation of 2-aminopyrimidines
BE788648A (fr) * 1971-10-09 1973-01-02 Soc D Etudes Prod Chimique Derives de l'isopropylamino pyrimidine, leur preparation leur composition et leur utilisation therapeutique
US3984414A (en) * 1971-10-09 1976-10-05 Societe D'etudes De Produits Chimiques Dichloroacetate salt of 2-isopropylamino pyrimidine
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Also Published As

Publication number Publication date
IT1148798B (it) 1986-12-03
AT375074B (de) 1984-06-25
LU82379A1 (fr) 1980-07-31
NO154057C (no) 1986-07-09
ES491004A0 (es) 1981-04-01
FR2456521B1 (es) 1982-10-01
HK55483A (en) 1983-11-25
SG22483G (en) 1983-12-16
IE800862L (en) 1980-11-15
SE8003241L (sv) 1980-11-16
DE3016549C2 (es) 1987-01-22
NL8002421A (nl) 1980-11-18
MX6295E (es) 1985-03-18
NO154057B (no) 1986-04-01
NO801236L (no) 1980-11-17
NZ193533A (en) 1982-03-23
OA06526A (fr) 1981-07-31
DK183980A (da) 1980-11-16
FR2456734A1 (fr) 1980-12-12
FI68045B (fi) 1985-03-29
AU5779080A (en) 1980-11-20
FR2456521A1 (fr) 1980-12-12
FI68045C (fi) 1985-07-10
BE882836A (fr) 1980-08-18
JPS6251271B2 (es) 1987-10-29
US4267181A (en) 1981-05-12
SE435177B (sv) 1984-09-10
MY8400201A (en) 1984-12-31
AR222872A1 (es) 1981-06-30
AU529581B2 (en) 1983-06-09
IE49708B1 (en) 1985-11-27
CH645103A5 (fr) 1984-09-14
ATA221480A (de) 1983-11-15
IN154370B (es) 1984-10-20
PT71162A (en) 1980-05-01
JPS55151571A (en) 1980-11-26
IT8021641A0 (it) 1980-04-24
MA18825A1 (fr) 1980-12-31
ZA802375B (en) 1981-06-24
CA1132562A (en) 1982-09-28
FR2456734B1 (es) 1982-10-08
FI801330A (fi) 1980-11-16
DE3016549A1 (de) 1980-11-27
EG14260A (en) 1983-09-30

Similar Documents

Publication Publication Date Title
ES479272A1 (es) Un procedimiento para la preparacion de esteres de acidos 17beta-tiocarboxilicos de 4-halo-3-oxoandrost-4-enos.
DE69208955T2 (de) Pyrimidin-4-carboxamidderivate, ihre Herstellung und ihre Verwendung in der Therapie
ATE12503T1 (de) 1-beta-d-arabinofuranosyl-(e)-5-(2halogensubstituiertes vinyl) uracil-5-phosphate; ihre herstellung und verwendung.
ES8104252A1 (es) Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina
ES448175A1 (es) Procedimiento para la preparacion de propargil-2-fenilamino-imidazolinas-(2).
AU571696B2 (en) 1-fluoro-1-azolyl-2,2-diphenylethane derivatives
ATE117552T1 (de) Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel.
DK160271C (da) Analogifremgangsmaade til fremstilling af 5-halogenvinyl-uracil-derivater
AU6469180A (en) 2-phenylamino-imidazolines-(2)
ES482742A1 (es) Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2)sustituidas
ATE32339T1 (de) Imidazolkarbonsaeure derivate.
ES460807A1 (es) Procedimiento para la produccion de compuestos de isoindoli-nona.
IL97289A0 (en) Tetraazaacenaphthylene-3-one derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
NO792099L (no) Analogifremgangsmaate for fremstilling av imidazolderivater og syreaddisjonssalter derav
ES481298A1 (es) Un procedimiento para preparar nuevos benzotiazo-derivados.
DK37582A (da) 2-pyridyloxyacetanilider,fremgangsmaade til deres fremstillingsamt deres anvendelse som herbicider
DK0614890T3 (da) Fremgangsmåde til fremstilling af eventuelt 2-substituerede 5-chlorimidazoler.
ES8205410A1 (es) Un procedimiento para preparar una pirazolo-piridinona
JPS5639090A (en) 5-substituted uracil derivative and its preparation
ES359831A1 (es) Procedimiento para la obtencion de tiazolo-pirimidinas sus-tituidas.
GB1453427A (en) 4-oxo-1,2,3,4-tetrahydropyrido-2,3-d-pyrimidines
TR21770A (tr) 2-piridiloksi asetik anilidler,bunlari hazirlamaya mahsus usul ve bunlarin herbisidler olarak kullanimi
FI953246A (fi) Välituotteet kinoliini-3-karboksyylihappojohdannaisten valmistamiseksi