ES8103056A1 - Un procedimiento para la preparacion de derivados de hidan- toina - Google Patents
Un procedimiento para la preparacion de derivados de hidan- toinaInfo
- Publication number
- ES8103056A1 ES8103056A1 ES489048A ES489048A ES8103056A1 ES 8103056 A1 ES8103056 A1 ES 8103056A1 ES 489048 A ES489048 A ES 489048A ES 489048 A ES489048 A ES 489048A ES 8103056 A1 ES8103056 A1 ES 8103056A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- cycloalkyl
- phenyl
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE LA HIDANTOINA DE FORMULA (I) EN LA QUE X ES IXIGENO O AZUFRE; Y ES UNA CADENA HIDROCARBONADA, SATURADA O INSATURADA, DE 2 ATOMOS DE CARBONO COMPATIBLE CON LA FUNCION ESTER; R2 ES HIDROGENO O ALQUILO INFERIOR; R3 ES HIDROXI; R4 ES ALQUILO, CICLOALQUILO O CICLOALQUILALQUILO Y R5 ES UN RESTO AMINICO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) EN LAS QUE LOS SIMBOLOS TIENEN LOS SIGNIFICADOS ANTES DADOS Y L REPRESENTA A UN GRUPO SALIENTE. ESTOS COMPUESTOS PRESENTAN ACTIVIDAD ANTISECRETORA GASTRICA, ANTIULCERAMENTE Y CARDIOVASCULAR, ENTRE OTRAS LOS QUE LOS HACE FARMACOLOGICAMENTE UTILES. *FORMULA*.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7827017 | 1978-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES489048A0 ES489048A0 (es) | 1981-02-16 |
ES8103056A1 true ES8103056A1 (es) | 1981-02-16 |
Family
ID=10497982
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481602A Expired ES481602A1 (es) | 1978-06-15 | 1979-06-15 | Un procedimiento para la preparacion de derivados de la hi- dantoina. |
ES489048A Expired ES8103056A1 (es) | 1978-06-15 | 1980-02-28 | Un procedimiento para la preparacion de derivados de hidan- toina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481602A Expired ES481602A1 (es) | 1978-06-15 | 1979-06-15 | Un procedimiento para la preparacion de derivados de la hi- dantoina. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4237131A (es) |
EP (1) | EP0006719A1 (es) |
JP (1) | JPS557271A (es) |
AU (1) | AU4807079A (es) |
DK (1) | DK249579A (es) |
ES (2) | ES481602A1 (es) |
IL (1) | IL57504A0 (es) |
PT (1) | PT69749A (es) |
ZA (1) | ZA792976B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2036192A1 (en) | 1990-02-13 | 1991-08-14 | Nicholas Meanwell | Heterocyclic carboxylic acids and esters |
US4970225A (en) * | 1990-02-13 | 1990-11-13 | Bristol-Myers Squibb Company | Imidazolidine carboxylic acids and esters as blood platelet aggregation inhibitors |
FR2706456B1 (fr) | 1993-06-18 | 1996-06-28 | Rhone Poulenc Agrochimie | Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
US6002016A (en) * | 1991-12-20 | 1999-12-14 | Rhone-Poulenc Agrochimie | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones |
DE4213634A1 (de) * | 1992-04-24 | 1993-10-28 | Cassella Ag | 2,4-Dioxo-imidazolidin-Derivate |
US6008370A (en) * | 1992-11-25 | 1999-12-28 | Rhone-Poulenc Agrochimie | Fungicidal-2-alkoxy/haloalkoxy-1-(mono- or disubstituted)amino-4,4-disubstituted-2-imidazolin-5-ones |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2323193A1 (de) * | 1972-05-10 | 1973-11-22 | Du Pont | Pyrazolidinone |
DE2451160A1 (de) * | 1973-10-30 | 1975-05-07 | Du Pont | 3-pyrazolidinone und pyrazolidine |
CA1176261A (en) * | 1976-06-03 | 1984-10-16 | Albert G. Caldwell | Hydantoin derivatives |
GB1598073A (en) * | 1976-12-18 | 1981-09-16 | Beecham Group Ltd | 8,10,12-triazaprostaglandins |
US4147796A (en) * | 1976-12-18 | 1979-04-03 | Beecham Group Limited | 1-(3-Hydroxyalk-1-yl)-5-(carboxyalkyl)hydantoin derivatives |
IL53559A0 (en) * | 1976-12-18 | 1978-03-10 | Beecham Group Ltd | Novel prostaglandin analogues their preparation and pharmaceutical compositions containing them |
DK391678A (da) * | 1977-09-05 | 1979-03-06 | Wellcome Found | Nitrogen-heterocycliske forbindelser fremgangsmaade til deres fremstilling samt deres anvendelse |
-
1979
- 1979-06-06 IL IL57504A patent/IL57504A0/xx unknown
- 1979-06-11 PT PT69749A patent/PT69749A/pt unknown
- 1979-06-14 US US06/048,516 patent/US4237131A/en not_active Expired - Lifetime
- 1979-06-14 DK DK249579A patent/DK249579A/da not_active Application Discontinuation
- 1979-06-14 EP EP79301144A patent/EP0006719A1/en not_active Ceased
- 1979-06-14 AU AU48070/79A patent/AU4807079A/en not_active Abandoned
- 1979-06-15 JP JP7556679A patent/JPS557271A/ja active Pending
- 1979-06-15 ZA ZA792976A patent/ZA792976B/xx unknown
- 1979-06-15 ES ES481602A patent/ES481602A1/es not_active Expired
-
1980
- 1980-02-28 ES ES489048A patent/ES8103056A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL57504A0 (en) | 1979-10-31 |
ES481602A1 (es) | 1980-06-16 |
DK249579A (da) | 1979-12-16 |
JPS557271A (en) | 1980-01-19 |
ES489048A0 (es) | 1981-02-16 |
ZA792976B (en) | 1980-08-27 |
US4237131A (en) | 1980-12-02 |
PT69749A (en) | 1979-07-01 |
EP0006719A1 (en) | 1980-01-09 |
AU4807079A (en) | 1979-12-20 |
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