ES8102579A1 - Un procedimiento para la preparacion de un nuevo esteroide 21-alquilado. - Google Patents

Un procedimiento para la preparacion de un nuevo esteroide 21-alquilado.

Info

Publication number
ES8102579A1
ES8102579A1 ES487966A ES487966A ES8102579A1 ES 8102579 A1 ES8102579 A1 ES 8102579A1 ES 487966 A ES487966 A ES 487966A ES 487966 A ES487966 A ES 487966A ES 8102579 A1 ES8102579 A1 ES 8102579A1
Authority
ES
Spain
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487966A
Other languages
English (en)
Other versions
ES487966A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of ES8102579A1 publication Critical patent/ES8102579A1/es
Publication of ES487966A0 publication Critical patent/ES487966A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN NUEVO ESTEROIDE 21-ALQUILADO DE FORMULA (I). *FORMULA* DONDE R1, R2, X E Y SON DISTINTOS TIPOS DE ATOMOS O RADICALES. SE ARACTERIZA POR HACER REACCIONAR EL CORRESPONDIENTE 21-DESALQUIL-17ALFA,21-DIHDIROXI-DERIVADO CON UN HALURO DE UN ACIDO SULFONICO ORGANICO Y EL 21-SULFONATO ASI OBTENIDO SE HACE REACCIOANR CON UN COMPUESTO DE LITIO-DIALQUIL-COBRE, DESPUES DE LO CUAL EL GRUPO 17ALFA-HIDROXI ES ACILADO CON PROTECCION TEMPORAL DEL GRUPO HIDROXI. TIENE APLICACIONES ANTIINFLAMATORIAS.
ES487966A 1979-01-24 1980-01-23 Un procedimiento para la preparacion de un nuevo esteroide 21-alquilado. Granted ES487966A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7902572 1979-01-24

Publications (2)

Publication Number Publication Date
ES8102579A1 true ES8102579A1 (es) 1981-01-16
ES487966A0 ES487966A0 (es) 1981-01-16

Family

ID=10502715

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487966A Granted ES487966A0 (es) 1979-01-24 1980-01-23 Un procedimiento para la preparacion de un nuevo esteroide 21-alquilado.

Country Status (12)

Country Link
US (1) US4260605A (es)
EP (1) EP0014005B1 (es)
JP (1) JPS55108893A (es)
AU (1) AU530981B2 (es)
CA (1) CA1160623A (es)
DE (1) DE3064460D1 (es)
DK (1) DK22180A (es)
ES (1) ES487966A0 (es)
FI (1) FI68843C (es)
HU (1) HU182091B (es)
IE (1) IE49360B1 (es)
ZA (1) ZA80215B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2605107A (en) * 1952-07-29 Multiple- valvei fluid control
US4686214A (en) * 1985-10-30 1987-08-11 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
JPS637844A (ja) * 1986-06-30 1988-01-13 Kubota Ltd 排オゾンの分解濾材
IL125004A0 (en) * 1995-12-20 1999-01-26 Schering Corp Process for the preparation of 9,11 beta-epoxide steroids
PL337458A1 (en) * 1997-06-04 2000-08-14 Akzo Nobel Nv Application of anti-inflammatory steroids in treating chronic intestinal inflammatory diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3064017A (en) * 1962-11-13 Preparation viii
US3045010A (en) * 1960-01-22 1962-07-17 Pfizer & Co C 21-methyl steroids and intermediates
NL275113A (es) * 1961-02-22
DE1167829B (de) * 1962-08-03 1964-04-16 Schering Ag Verfahren zur Herstellung von 21-Methyl-í¸-pregnen-11ª‰, 17ª‡-diol-3, 20-dion
GB1416427A (en) * 1972-01-12 1975-12-03 Akzo Nv Alkylated pregnanes and process for obtaining same
GB1478968A (en) * 1973-07-11 1977-07-06 Akzo Nv Alkylated pregnanes

Also Published As

Publication number Publication date
FI68843C (fi) 1985-11-11
FI68843B (fi) 1985-07-31
JPS6337798B2 (es) 1988-07-27
IE49360B1 (en) 1985-09-18
US4260605A (en) 1981-04-07
DE3064460D1 (en) 1983-09-08
HU182091B (en) 1983-12-28
AU530981B2 (en) 1983-08-04
IE800050L (en) 1980-07-24
AU5469180A (en) 1980-07-31
FI800161A (fi) 1980-07-25
JPS55108893A (en) 1980-08-21
ES487966A0 (es) 1981-01-16
EP0014005A1 (en) 1980-08-06
EP0014005B1 (en) 1983-08-03
DK22180A (da) 1980-07-25
ZA80215B (en) 1980-12-31
CA1160623A (en) 1984-01-17

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