ES8102111A1 - Procedimiento para la preparacion de n-dialcohilaminome- til-s,s-diarilsulfoximidas - Google Patents
Procedimiento para la preparacion de n-dialcohilaminome- til-s,s-diarilsulfoximidasInfo
- Publication number
- ES8102111A1 ES8102111A1 ES491696A ES491696A ES8102111A1 ES 8102111 A1 ES8102111 A1 ES 8102111A1 ES 491696 A ES491696 A ES 491696A ES 491696 A ES491696 A ES 491696A ES 8102111 A1 ES8102111 A1 ES 8102111A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- formula
- obtaining
- aryl
- appropriate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE N-DIALCOHILAMINOMETIL-S, S-DIARILSULFOXIMIDAS DE FORMULA (I), DONDE R1 Y R2 REPRESENTAN UN RADICAL ARILO, Y R3 Y R4, QUE PUEDEN SER IGUALES O DISTINTOS , SIGNIFICAN UN ALCOHILO DE CADENA RECTA O RAMIFICADA. TANTO LOS RADICALES ARILO COMO LOS ALCOHILO PUEDEN PRESENTARSE SUSTITUIDOS O EN COMUN, RESPECTIVAMENTE, CON EL AZUFRE O EL NITROGENO PARA CONSTITUIR UN SISTEMA HETEROCICLICO. EL PROCEDIMIENTO DE OBTENCION CONSTA DE LA REACCION DE LA S,S-DIARILSULFOXIMIDA ADECUADA, EN UN DISOLVENTE NO MISCIBLE EN AGUA, CON FORMALDEHIDO Y CON LA AMINA SECUNDARIA APROPIADA. EL COMPUESTO EVENTUALMENTE OBTENIDO SE TRANSFORMA EN SU SAL TERCIARIA O CUATERNARIA. ESTOS COMPUESTOS PRESENTAN PROPIEDADES ESPASMOLITICAS DE INTERES FARMACOLOGICO. *FORMULA*
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2920958A DE2920958C2 (de) | 1979-05-23 | 1979-05-23 | Verfahren zur Herstellung von S,S-Diarylsulfoximidderivaten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8102111A1 true ES8102111A1 (es) | 1981-01-16 |
| ES491696A0 ES491696A0 (es) | 1981-01-16 |
Family
ID=6071557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491696A Granted ES491696A0 (es) | 1979-05-23 | 1980-05-21 | Procedimiento para la preparacion de n-dialcohilaminome- til-s,s-diarilsulfoximidas |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5625151A (es) |
| AR (1) | AR225039A1 (es) |
| AT (1) | AT371805B (es) |
| DD (1) | DD150896A5 (es) |
| DE (1) | DE2920958C2 (es) |
| ES (1) | ES491696A0 (es) |
| HU (1) | HU180140B (es) |
| IT (1) | IT1140964B (es) |
| PT (1) | PT71284A (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9000303D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Therapeutic agents |
-
1979
- 1979-05-23 DE DE2920958A patent/DE2920958C2/de not_active Expired
-
1980
- 1980-05-05 AT AT0237880A patent/AT371805B/de not_active IP Right Cessation
- 1980-05-20 AR AR281124A patent/AR225039A1/es active
- 1980-05-20 IT IT22192/80A patent/IT1140964B/it active
- 1980-05-21 ES ES491696A patent/ES491696A0/es active Granted
- 1980-05-21 HU HU801273A patent/HU180140B/hu unknown
- 1980-05-21 JP JP6838880A patent/JPS5625151A/ja active Pending
- 1980-05-21 PT PT71284A patent/PT71284A/pt unknown
- 1980-05-22 DD DD80221317A patent/DD150896A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU180140B (en) | 1983-02-28 |
| JPS5625151A (en) | 1981-03-10 |
| AR225039A1 (es) | 1982-02-15 |
| DE2920958C2 (de) | 1981-06-11 |
| IT8022192A0 (it) | 1980-05-20 |
| AT371805B (de) | 1983-08-10 |
| ATA237880A (de) | 1982-12-15 |
| DD150896A5 (de) | 1981-09-23 |
| ES491696A0 (es) | 1981-01-16 |
| DE2920958B1 (de) | 1980-09-18 |
| PT71284A (de) | 1980-06-01 |
| IT1140964B (it) | 1986-10-10 |
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