ES550966A0 - Un procedimiento para la preparacion de nuevos benzotiofenos - Google Patents

Un procedimiento para la preparacion de nuevos benzotiofenos

Info

Publication number
ES550966A0
ES550966A0 ES550966A ES550966A ES550966A0 ES 550966 A0 ES550966 A0 ES 550966A0 ES 550966 A ES550966 A ES 550966A ES 550966 A ES550966 A ES 550966A ES 550966 A0 ES550966 A0 ES 550966A0
Authority
ES
Spain
Prior art keywords
benzothiophenes
procedure
preparation
new
new benzothiophenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES550966A
Other languages
English (en)
Other versions
ES8800678A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/705,115 external-priority patent/US4760086A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES550966A0 publication Critical patent/ES550966A0/es
Publication of ES8800678A1 publication Critical patent/ES8800678A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES550966A 1984-04-02 1986-01-16 Un procedimiento para la preparacion de nuevos benzotiofenos Expired ES8800678A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59613484A 1984-04-02 1984-04-02
US06/705,115 US4760086A (en) 1985-02-27 1985-02-27 N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors

Publications (2)

Publication Number Publication Date
ES550966A0 true ES550966A0 (es) 1987-11-16
ES8800678A1 ES8800678A1 (es) 1987-11-16

Family

ID=27082470

Family Applications (2)

Application Number Title Priority Date Filing Date
ES541781A Expired ES8705419A1 (es) 1984-04-02 1985-03-29 Un procedimiento para la preparacion de nuevos benzotiopenos.
ES550966A Expired ES8800678A1 (es) 1984-04-02 1986-01-16 Un procedimiento para la preparacion de nuevos benzotiofenos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES541781A Expired ES8705419A1 (es) 1984-04-02 1985-03-29 Un procedimiento para la preparacion de nuevos benzotiopenos.

Country Status (10)

Country Link
EP (1) EP0160408B1 (es)
KR (1) KR870000288B1 (es)
AU (1) AU572637B2 (es)
CA (1) CA1298837C (es)
DE (1) DE3572487D1 (es)
DK (1) DK145585A (es)
ES (2) ES8705419A1 (es)
GR (1) GR850765B (es)
IL (1) IL74694A0 (es)
PT (1) PT80184B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703053A (en) * 1985-10-28 1987-10-27 Warner-Lambert Company Benzothiophenes and benzofurans and antiallergic use thereof
US4720503A (en) * 1985-08-02 1988-01-19 Merck & Co., Inc. N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
EP0253650A3 (en) * 1986-07-18 1989-09-13 Eli Lilly And Company Improvements relating to benzothiophene derivatives
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
US5217968A (en) * 1989-04-06 1993-06-08 Pfizer Inc. N-alkylbenzo(b)thieno [3,2-b]oxazin-2,4-diones
EP0403885A1 (de) * 1989-06-20 1990-12-27 Bayer Ag Verwendung von 3-Hydroxybenzothiophenen zur Bekämpfung von Endoparasiten, neue 3-Hydroxybenzothiophene und Verfahren zu ihrer Herstellung
US5223502A (en) * 1989-09-27 1993-06-29 Bayer Aktiengesellschaft Insecticidal 1,2,3,4-tetrahydro-5-nitropyrrolopyrimidine derivatives
DE4115184A1 (de) * 1991-05-09 1992-11-12 Bayer Ag Benzothiophen-2-carboxamid-s,s-dioxide
ES2087463T3 (es) * 1991-11-18 1996-07-16 Lilly Industries Ltd Benzo(b)tiofen-2-carboxamidas para el tratamiento de trastornos del sistema nervioso central.
GB9218113D0 (en) * 1992-08-26 1992-10-14 Lilly Industries Ltd Pharmaceutical compounds
DE4328074A1 (de) * 1993-08-20 1995-02-23 Bayer Ag Schimmelfeste Dispersionsfarbenanstriche
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
DE19548428C1 (de) * 1995-12-22 1997-08-28 Hoechst Ag 2-Alkylmerkapto-4-(trifluormethyl)-benzoesäureester sowie ein Verfahren zu ihrer Herstellung
US6013674A (en) * 1997-06-02 2000-01-11 Eli Lilly And Company Cell adhesion inhibitors
CA2677769C (en) 2007-02-16 2016-01-19 Ono Pharmaceutical Co., Ltd. Therapeutic agent for urinary excretion disorder
EP2772136B1 (en) 2007-10-15 2015-09-09 The Salk Institute for Biological Studies Methods for treating a variety of diseases and conditions, and compounds useful therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC807A1 (fr) * 1968-07-29 1970-07-30 Soc Et Scient Et Ind De L Ile Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non
DE2258036A1 (de) * 1972-11-27 1974-05-30 Goedecke Ag Verfahren zur herstellung von benzo eckige klammer auf b eckige klammer zu thiophen-derivaten

Also Published As

Publication number Publication date
DK145585A (da) 1985-10-03
EP0160408B1 (en) 1989-08-23
AU4056485A (en) 1985-10-10
CA1298837C (en) 1992-04-14
PT80184B (en) 1987-03-20
ES8705419A1 (es) 1987-05-01
IL74694A0 (en) 1985-06-30
PT80184A (en) 1985-04-01
KR850008342A (ko) 1985-12-16
EP0160408A1 (en) 1985-11-06
DK145585D0 (da) 1985-04-01
KR870000288B1 (ko) 1987-02-25
ES541781A0 (es) 1987-05-01
AU572637B2 (en) 1988-05-12
ES8800678A1 (es) 1987-11-16
GR850765B (es) 1985-11-25
DE3572487D1 (en) 1989-09-28

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