IL74694A0 - N-alkenyl-3-hydroxybenzo(b)thiophene-2-carboxamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
N-alkenyl-3-hydroxybenzo(b)thiophene-2-carboxamide derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL74694A0 IL74694A0 IL74694A IL7469485A IL74694A0 IL 74694 A0 IL74694 A0 IL 74694A0 IL 74694 A IL74694 A IL 74694A IL 7469485 A IL7469485 A IL 7469485A IL 74694 A0 IL74694 A0 IL 74694A0
- Authority
- IL
- Israel
- Prior art keywords
- hydroxybenzo
- thiophene
- alkenyl
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59613484A | 1984-04-02 | 1984-04-02 | |
US06/705,115 US4760086A (en) | 1985-02-27 | 1985-02-27 | N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IL74694A0 true IL74694A0 (en) | 1985-06-30 |
Family
ID=27082470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL74694A IL74694A0 (en) | 1984-04-02 | 1985-03-22 | N-alkenyl-3-hydroxybenzo(b)thiophene-2-carboxamide derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0160408B1 (xx) |
KR (1) | KR870000288B1 (xx) |
AU (1) | AU572637B2 (xx) |
CA (1) | CA1298837C (xx) |
DE (1) | DE3572487D1 (xx) |
DK (1) | DK145585A (xx) |
ES (2) | ES8705419A1 (xx) |
GR (1) | GR850765B (xx) |
IL (1) | IL74694A0 (xx) |
PT (1) | PT80184B (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4703053A (en) * | 1985-10-28 | 1987-10-27 | Warner-Lambert Company | Benzothiophenes and benzofurans and antiallergic use thereof |
US4720503A (en) * | 1985-08-02 | 1988-01-19 | Merck & Co., Inc. | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
EP0253650A3 (en) * | 1986-07-18 | 1989-09-13 | Eli Lilly And Company | Improvements relating to benzothiophene derivatives |
US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
WO1990011763A1 (en) * | 1989-04-06 | 1990-10-18 | Pfizer Inc. | N-ALKENYLBENZO[b]THIENO[3,2-b]OXAZIN-2,4-DIONES |
EP0403885A1 (de) * | 1989-06-20 | 1990-12-27 | Bayer Ag | Verwendung von 3-Hydroxybenzothiophenen zur Bekämpfung von Endoparasiten, neue 3-Hydroxybenzothiophene und Verfahren zu ihrer Herstellung |
US5223502A (en) * | 1989-09-27 | 1993-06-29 | Bayer Aktiengesellschaft | Insecticidal 1,2,3,4-tetrahydro-5-nitropyrrolopyrimidine derivatives |
DE4115184A1 (de) * | 1991-05-09 | 1992-11-12 | Bayer Ag | Benzothiophen-2-carboxamid-s,s-dioxide |
DE69210959T2 (de) * | 1991-11-18 | 1996-09-26 | Lilly Industries Ltd | Benzo(b)thiophen-2-carboxamide zur Behandlung von Krankheiten des Zentralnervensystems |
GB9218113D0 (en) * | 1992-08-26 | 1992-10-14 | Lilly Industries Ltd | Pharmaceutical compounds |
DE4328074A1 (de) * | 1993-08-20 | 1995-02-23 | Bayer Ag | Schimmelfeste Dispersionsfarbenanstriche |
US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
DE19548428C1 (de) * | 1995-12-22 | 1997-08-28 | Hoechst Ag | 2-Alkylmerkapto-4-(trifluormethyl)-benzoesäureester sowie ein Verfahren zu ihrer Herstellung |
US6013674A (en) * | 1997-06-02 | 2000-01-11 | Eli Lilly And Company | Cell adhesion inhibitors |
BRPI0807942A2 (pt) | 2007-02-16 | 2014-07-01 | Ono Pharmaceutical Co | Agente terapêutico para distúrbio de excreção urinária |
EP2205072B1 (en) * | 2007-10-15 | 2013-11-20 | The Salk Institute for Biological Studies | Methods for treating a variety of diseases and conditions, and compounds useful therefor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MC807A1 (fr) * | 1968-07-29 | 1970-07-30 | Soc Et Scient Et Ind De L Ile | Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non |
DE2258036A1 (de) * | 1972-11-27 | 1974-05-30 | Goedecke Ag | Verfahren zur herstellung von benzo eckige klammer auf b eckige klammer zu thiophen-derivaten |
-
1985
- 1985-03-22 IL IL74694A patent/IL74694A0/xx unknown
- 1985-03-27 GR GR850765A patent/GR850765B/el unknown
- 1985-03-28 CA CA000477848A patent/CA1298837C/en not_active Expired - Fee Related
- 1985-03-28 PT PT80184A patent/PT80184B/pt unknown
- 1985-03-29 ES ES541781A patent/ES8705419A1/es not_active Expired
- 1985-04-01 DE DE8585302275T patent/DE3572487D1/de not_active Expired
- 1985-04-01 EP EP85302275A patent/EP0160408B1/en not_active Expired
- 1985-04-01 DK DK145585A patent/DK145585A/da not_active IP Right Cessation
- 1985-04-01 AU AU40564/85A patent/AU572637B2/en not_active Expired - Fee Related
- 1985-04-01 KR KR1019850002176A patent/KR870000288B1/ko active IP Right Grant
-
1986
- 1986-01-16 ES ES550966A patent/ES8800678A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES541781A0 (es) | 1987-05-01 |
AU572637B2 (en) | 1988-05-12 |
PT80184A (en) | 1985-04-01 |
EP0160408A1 (en) | 1985-11-06 |
DE3572487D1 (en) | 1989-09-28 |
DK145585A (da) | 1985-10-03 |
PT80184B (en) | 1987-03-20 |
ES8705419A1 (es) | 1987-05-01 |
DK145585D0 (da) | 1985-04-01 |
ES550966A0 (es) | 1987-11-16 |
GR850765B (xx) | 1985-11-25 |
EP0160408B1 (en) | 1989-08-23 |
ES8800678A1 (es) | 1987-11-16 |
AU4056485A (en) | 1985-10-10 |
KR850008342A (ko) | 1985-12-16 |
KR870000288B1 (ko) | 1987-02-25 |
CA1298837C (en) | 1992-04-14 |
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