ES538903A0 - Procedimiento para la preparacion de agentes anti-psoriaticos del tipo naftalenico - Google Patents

Procedimiento para la preparacion de agentes anti-psoriaticos del tipo naftalenico

Info

Publication number
ES538903A0
ES538903A0 ES538903A ES538903A ES538903A0 ES 538903 A0 ES538903 A0 ES 538903A0 ES 538903 A ES538903 A ES 538903A ES 538903 A ES538903 A ES 538903A ES 538903 A0 ES538903 A0 ES 538903A0
Authority
ES
Spain
Prior art keywords
optionally substituted
substituted phenyl
lower alkyl
alkyl
naftalenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES538903A
Other languages
English (en)
Other versions
ES8600730A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES8600730A1 publication Critical patent/ES8600730A1/es
Publication of ES538903A0 publication Critical patent/ES538903A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C07C205/46Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group the carbon skeleton containing carbon atoms of quinone rings
    • C07C205/47Anthraquinones containing nitro groups
    • C07C205/48Anthraquinones containing nitro groups the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/57Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • C07C46/02Preparation of quinones by oxidation giving rise to quinoid structures
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/24Quinones containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Luminescent Compositions (AREA)
  • Organic Insulating Materials (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Multiple-Way Valves (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ES538903A 1983-12-22 1984-12-20 Procedimiento para la preparacion de agentes anti-psoriaticos del tipo naftalenico Granted ES538903A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/564,155 US4593120A (en) 1982-10-27 1983-12-22 Naphthalene anti-psoriatic agents

Publications (2)

Publication Number Publication Date
ES8600730A1 ES8600730A1 (es) 1985-11-01
ES538903A0 true ES538903A0 (es) 1985-11-01

Family

ID=24253366

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538903A Granted ES538903A0 (es) 1983-12-22 1984-12-20 Procedimiento para la preparacion de agentes anti-psoriaticos del tipo naftalenico

Country Status (15)

Country Link
US (1) US4593120A (es)
EP (1) EP0146145B1 (es)
JP (1) JPS60156642A (es)
KR (1) KR850004574A (es)
AT (1) ATE45877T1 (es)
AU (1) AU580277B2 (es)
DE (1) DE3479563D1 (es)
DK (1) DK617284A (es)
ES (1) ES538903A0 (es)
FI (1) FI845047L (es)
HU (1) HU195471B (es)
IL (1) IL73878A0 (es)
NO (1) NO160360C (es)
NZ (1) NZ210666A (es)
ZA (1) ZA849959B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466981A (en) * 1982-10-27 1984-08-21 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
ATE36316T1 (de) * 1984-01-27 1988-08-15 Syntex Inc Gegen psoriasis wirkende naphthalin-verbindungen.
US4833164A (en) * 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
SU1600627A3 (ru) * 1985-05-08 1990-10-15 Е.И.Дюпон Де Немур Энд Компани (Фирма) Способ получени 2-замещенных 1-нафтолов
US4792556A (en) * 1985-09-09 1988-12-20 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
ZA866823B (en) * 1985-09-09 1988-04-27 Syntex Inc Naphthalene anti-psoritic agents
HU199778B (en) * 1987-03-09 1990-03-28 Syntex Inc Process for production of derivatives of naphtaline against psioriasis and medical compositions containing them
US5134161A (en) * 1987-03-09 1992-07-28 Syntex (U.S.A.) Inc. Method for treating disease states in mammals with naphthalene lipoxygenase-inhibiting agents
US4786652A (en) * 1987-03-09 1988-11-22 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
US4882339A (en) * 1987-07-10 1989-11-21 Ciba-Geigy Corporation 4-Amino-substituted 1,2-dihydroxynaphthalene derivatives useful in inhibiting 5-lipoxygenase activity in mammals
US5242946A (en) * 1988-10-27 1993-09-07 Bio-Mega, Inc. Treating herpes Viral infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466981A (en) * 1982-10-27 1984-08-21 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
ATE36316T1 (de) * 1984-01-27 1988-08-15 Syntex Inc Gegen psoriasis wirkende naphthalin-verbindungen.
JPH0520420A (ja) * 1991-07-12 1993-01-29 Brother Ind Ltd 図形処理装置

Also Published As

Publication number Publication date
KR850004574A (ko) 1985-07-25
AU3711984A (en) 1985-07-04
FI845047A0 (fi) 1984-12-20
NO160360B (no) 1989-01-02
NZ210666A (en) 1988-06-30
ES8600730A1 (es) 1985-11-01
FI845047L (fi) 1985-06-23
HUT36079A (en) 1985-08-28
US4593120A (en) 1986-06-03
DE3479563D1 (en) 1989-10-05
HU195471B (en) 1988-05-30
AU580277B2 (en) 1989-01-12
NO160360C (no) 1989-04-12
JPS60156642A (ja) 1985-08-16
IL73878A0 (en) 1985-03-31
NO845147L (no) 1985-06-24
DK617284D0 (da) 1984-12-20
ZA849959B (en) 1986-08-27
EP0146145A3 (en) 1986-04-16
EP0146145A2 (en) 1985-06-26
EP0146145B1 (en) 1989-08-30
DK617284A (da) 1985-06-23
ATE45877T1 (de) 1989-09-15

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