ES528481A0 - Un procedimiento para la preparacion de una quinazolina - Google Patents

Un procedimiento para la preparacion de una quinazolina

Info

Publication number
ES528481A0
ES528481A0 ES528481A ES528481A ES528481A0 ES 528481 A0 ES528481 A0 ES 528481A0 ES 528481 A ES528481 A ES 528481A ES 528481 A ES528481 A ES 528481A ES 528481 A0 ES528481 A0 ES 528481A0
Authority
ES
Spain
Prior art keywords
quinazoline
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES528481A
Other languages
English (en)
Other versions
ES8504793A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Pfizer Inc
Original Assignee
Pfizer Corp
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp, Pfizer Inc filed Critical Pfizer Corp
Publication of ES8504793A1 publication Critical patent/ES8504793A1/es
Publication of ES528481A0 publication Critical patent/ES528481A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES528481A 1982-05-15 1983-12-28 Un procedimiento para la preparacion de una quinazolina Granted ES528481A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8214206 1982-05-15

Publications (2)

Publication Number Publication Date
ES8504793A1 ES8504793A1 (es) 1985-05-01
ES528481A0 true ES528481A0 (es) 1985-05-01

Family

ID=10530384

Family Applications (3)

Application Number Title Priority Date Filing Date
ES522278A Expired ES8407039A1 (es) 1982-05-15 1983-05-11 Un procedimiento para preparacion de una quinalozina.
ES528481A Granted ES528481A0 (es) 1982-05-15 1983-12-28 Un procedimiento para la preparacion de una quinazolina
ES528482A Expired ES8504794A1 (es) 1982-05-15 1983-12-28 Un procedimiento para la preparacion de una quinazolina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES522278A Expired ES8407039A1 (es) 1982-05-15 1983-05-11 Un procedimiento para preparacion de una quinalozina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES528482A Expired ES8504794A1 (es) 1982-05-15 1983-12-28 Un procedimiento para la preparacion de una quinazolina

Country Status (22)

Country Link
US (1) US4489075A (es)
EP (1) EP0094766B1 (es)
JP (1) JPS58208289A (es)
KR (1) KR840004747A (es)
AU (1) AU538171B2 (es)
CA (1) CA1195977A (es)
DD (2) DD216018A5 (es)
DE (1) DE3368631D1 (es)
DK (1) DK210183A (es)
ES (3) ES8407039A1 (es)
FI (1) FI831684L (es)
GR (1) GR77498B (es)
IL (1) IL68668A0 (es)
IN (1) IN160680B (es)
NO (1) NO831728L (es)
NZ (1) NZ204225A (es)
PH (1) PH18763A (es)
PL (2) PL247054A1 (es)
PT (1) PT76687B (es)
SU (1) SU1194257A3 (es)
YU (1) YU105083A (es)
ZA (1) ZA833422B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US5138062A (en) * 1989-10-03 1992-08-11 Philip Morris Incorporated Nicotine analogs
BR9205811A (pt) * 1991-03-28 1994-06-28 Pfizer Derivados heterociclicos de aminas ciclicas
PL3143019T3 (pl) * 2014-05-15 2021-03-22 Pfizer Inc. Krystaliczna postać 6-[(4R)-4-metylo-1,2-dioksydo-1,2,6-tiadiazynan-2-ylo]izochinolino-1-karbonitrylu

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971783A (en) * 1973-03-07 1976-07-27 Pfizer Inc. 4-Aminoquinazoline derivatives as cardiac stimulants
GB1460389A (en) * 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants
US4171363A (en) * 1977-02-22 1979-10-16 Bristol-Myers Company 1,2,3-Thiadiazole process
CA1086735A (en) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines

Also Published As

Publication number Publication date
FI831684A0 (fi) 1983-05-13
KR840004747A (ko) 1984-10-24
AU538171B2 (en) 1984-08-02
IL68668A0 (en) 1983-09-30
EP0094766A3 (en) 1984-12-12
US4489075A (en) 1984-12-18
ES8504793A1 (es) 1985-05-01
AU1452283A (en) 1983-11-17
ES522278A0 (es) 1984-08-16
NZ204225A (en) 1985-12-13
DK210183A (da) 1983-11-16
FI831684L (fi) 1983-11-16
YU105083A (en) 1986-02-28
ES528482A0 (es) 1985-05-01
EP0094766A2 (en) 1983-11-23
PL241968A1 (en) 1984-08-13
EP0094766B1 (en) 1986-12-30
GR77498B (es) 1984-09-24
DE3368631D1 (de) 1987-02-05
PL247054A1 (en) 1985-03-26
SU1194257A3 (ru) 1985-11-23
JPS58208289A (ja) 1983-12-03
NO831728L (no) 1983-11-16
DD216018A5 (de) 1984-11-28
PH18763A (en) 1985-09-20
ES8407039A1 (es) 1984-08-16
CA1195977A (en) 1985-10-29
ES8504794A1 (es) 1985-05-01
PT76687B (en) 1986-03-27
DK210183D0 (da) 1983-05-11
IN160680B (es) 1987-07-25
ZA833422B (en) 1984-02-29
DD210269A5 (de) 1984-06-06
PT76687A (en) 1983-06-01

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