ES517865A0 - Un procedimiento para la preparacion de pirimidin-2-onas-sustituidas. - Google Patents
Un procedimiento para la preparacion de pirimidin-2-onas-sustituidas.Info
- Publication number
- ES517865A0 ES517865A0 ES517865A ES517865A ES517865A0 ES 517865 A0 ES517865 A0 ES 517865A0 ES 517865 A ES517865 A ES 517865A ES 517865 A ES517865 A ES 517865A ES 517865 A0 ES517865 A0 ES 517865A0
- Authority
- ES
- Spain
- Prior art keywords
- sup
- sub
- group
- ring
- heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8100613 | 1981-01-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES517865A0 true ES517865A0 (es) | 1984-06-16 |
| ES8405771A1 ES8405771A1 (es) | 1984-06-16 |
Family
ID=10518891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508593A Expired ES8304945A1 (es) | 1981-01-09 | 1982-01-08 | "un procedimiento para la preparacion de pirimidin-2-onas sustituidas". |
| ES517865A Expired ES8405771A1 (es) | 1981-01-09 | 1982-12-01 | Un procedimiento para la preparacion de pirimidin-2-onas-sustituidas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508593A Expired ES8304945A1 (es) | 1981-01-09 | 1982-01-08 | "un procedimiento para la preparacion de pirimidin-2-onas sustituidas". |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US4596870A (es) |
| EP (1) | EP0056319B1 (es) |
| JP (1) | JPS57136575A (es) |
| AT (1) | ATE19242T1 (es) |
| AU (1) | AU7929482A (es) |
| CA (1) | CA1180710A (es) |
| DE (1) | DE3270525D1 (es) |
| DK (1) | DK5382A (es) |
| ES (2) | ES8304945A1 (es) |
| NO (1) | NO160514C (es) |
| NZ (1) | NZ199447A (es) |
| ZA (1) | ZA82125B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK83783A (da) * | 1982-02-24 | 1983-08-25 | Nyegaard & Co As | Fremgangsmaade til fremstilling af substituerede pyrimidin-2-oner |
| GB2135992B (en) * | 1983-01-11 | 1986-09-24 | Nyegaard & Co As | Substituted pyrimidines and processes for their preparation |
| EP0119457B1 (de) * | 1983-02-23 | 1986-12-30 | Bayer Ag | Mittel zur Regulierung des Pflanzenwachstums |
| GB8411291D0 (en) * | 1984-05-02 | 1984-06-06 | Nyegaard & Co As | Chemical compounds |
| US4864021A (en) * | 1984-10-30 | 1989-09-05 | Otsuka Pharmaceutical Co., Ltd. | 5-fluorouracil derivatives |
| US4675321A (en) * | 1986-02-07 | 1987-06-23 | Merck & Co., Inc. | Substituted pyrimidines useful as calcium channel blockers |
| US4849426A (en) * | 1987-05-15 | 1989-07-18 | Pearlman Dale L | Method for treating actinic keratosis with cytotoxic agents |
| US4820711A (en) * | 1987-05-15 | 1989-04-11 | Pearlman Dale L | Method for treating actinic keratosis with cytotoxic agents |
| US4853388A (en) * | 1987-05-15 | 1989-08-01 | Pearlman Dale L | Method for treating psoriasis with cytotoxic agents |
| US8933239B1 (en) * | 2013-07-16 | 2015-01-13 | Dow Global Technologies Llc | Bis(aryl)acetal compounds |
| GB201321734D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1561290A (en) * | 1975-10-16 | 1980-02-20 | Nyegaard & Co As | Pyrimid - 2 - ones |
| US4044008A (en) * | 1976-10-06 | 1977-08-23 | Morton-Norwich Products, Inc. | 1-[2-Hydroxy-3-(2-naphthoxy)propyl]-2(1H)pyrimidone hydrochloride |
| ES498337A0 (es) * | 1980-01-07 | 1982-06-01 | Nyegaard & Co As | Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas |
| NZ195992A (en) * | 1980-01-10 | 1983-11-30 | Nyegaard & Co As | 5-halopyrimidines;their 2-sulphides and s-oxides;pharmaceutical compositions |
| DK83783A (da) * | 1982-02-24 | 1983-08-25 | Nyegaard & Co As | Fremgangsmaade til fremstilling af substituerede pyrimidin-2-oner |
-
1982
- 1982-01-08 JP JP57001098A patent/JPS57136575A/ja active Pending
- 1982-01-08 CA CA000393785A patent/CA1180710A/en not_active Expired
- 1982-01-08 NO NO820049A patent/NO160514C/no unknown
- 1982-01-08 US US06/337,988 patent/US4596870A/en not_active Expired - Fee Related
- 1982-01-08 EP EP82300106A patent/EP0056319B1/en not_active Expired
- 1982-01-08 AU AU79294/82A patent/AU7929482A/en not_active Abandoned
- 1982-01-08 DE DE8282300106T patent/DE3270525D1/de not_active Expired
- 1982-01-08 NZ NZ199447A patent/NZ199447A/en unknown
- 1982-01-08 ES ES508593A patent/ES8304945A1/es not_active Expired
- 1982-01-08 AT AT82300106T patent/ATE19242T1/de not_active IP Right Cessation
- 1982-01-08 DK DK5382A patent/DK5382A/da not_active Application Discontinuation
- 1982-01-08 ZA ZA82125A patent/ZA82125B/xx unknown
- 1982-12-01 ES ES517865A patent/ES8405771A1/es not_active Expired
-
1986
- 1986-04-08 US US06/849,271 patent/US4705791A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0056319A3 (en) | 1982-10-27 |
| DK5382A (da) | 1982-07-10 |
| US4596870A (en) | 1986-06-24 |
| EP0056319B1 (en) | 1986-04-16 |
| ES508593A0 (es) | 1983-03-16 |
| ATE19242T1 (de) | 1986-05-15 |
| NO160514C (no) | 1989-04-26 |
| NO160514B (no) | 1989-01-16 |
| NO820049L (no) | 1982-07-12 |
| DE3270525D1 (en) | 1986-05-22 |
| ES8405771A1 (es) | 1984-06-16 |
| CA1180710A (en) | 1985-01-08 |
| ES8304945A1 (es) | 1983-03-16 |
| JPS57136575A (en) | 1982-08-23 |
| EP0056319A2 (en) | 1982-07-21 |
| NZ199447A (en) | 1985-08-16 |
| ZA82125B (en) | 1982-12-29 |
| US4705791A (en) | 1987-11-10 |
| AU7929482A (en) | 1982-07-15 |
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