ES2057455T3 - Procedimiento de preparacion de isomeros opticos de los derivados de la 1,4-dihidro-piridina. - Google Patents

Procedimiento de preparacion de isomeros opticos de los derivados de la 1,4-dihidro-piridina.

Info

Publication number
ES2057455T3
ES2057455T3 ES90400096T ES90400096T ES2057455T3 ES 2057455 T3 ES2057455 T3 ES 2057455T3 ES 90400096 T ES90400096 T ES 90400096T ES 90400096 T ES90400096 T ES 90400096T ES 2057455 T3 ES2057455 T3 ES 2057455T3
Authority
ES
Spain
Prior art keywords
radical
carbon atoms
denotes
piridine
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90400096T
Other languages
English (en)
Inventor
Jean Louis Peglion
Bernard Serkiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2057455T3 publication Critical patent/ES2057455T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

EL INVENTO CONSISTE EN UN NUEVO PROCESO DE SEPARACION DE ISOMEROS OPTICOS DE LOS COMPUESTOS DE FORMULA (I), DONDE: AR REPRESENTA UN RADICAL FENILO, COMPORTANDO EVENTUALMENTE DE 1 A 5 SUSTITUYENTES IDENTICOS O DIFERENTES REPRESENTANDO CADA UNO, UN ATOMO DE HALOGENO, UN RADICAL ALCOXI CONTENIENDO DE 1 A 4 ATOMOS DE CARBONO, UN RADICAL ALQUILTIO CONTENIENDO DE 1 A 4 ATOMOS DE CARBONO, UN RADICAL TRIHALOGENOMETILO O UN RADICAL METILENODIOXI; Y, Z, Y1 Y Z1, IDENTICOS O DIFERENTES REPRESENTAN CADA UNO UN ATOMO DE HIDROGENO, UN RADICAL ALQUILO INFERIOR LINEAL O RAMIFICADO CONTENIENDO DE 1 A 4 ATOMOS DE CARBONO, UN RADICAL CICLOPROPILO, UN RADICAL DICICLOPROPILMETILO, UN RADICAL DICICLOPROPIL-2,2 ETILO, UN RADICAL DICICLOPROPIL-2,2 ETILENO, UN RADICAL DICICLOPROPIL-3,3 PROPILO, UN RADICAL DICICLOPROPIL-3,3 PROPILENO-1, UN RADICAL ALQUILENO LINEAL O RAMIFICADO CONTENIENDO DE 2 A 5 ATOMOS DE CARBONO O UN RADICAL FENILO EVENTUALMENTE SUSTITUIDO POR UN RADICAL NITRO; Y N ES IGUAL A 1, 2 O 3.
ES90400096T 1989-09-20 1990-01-15 Procedimiento de preparacion de isomeros opticos de los derivados de la 1,4-dihidro-piridina. Expired - Lifetime ES2057455T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8912323A FR2652083B1 (fr) 1989-09-20 1989-09-20 Nouveau procede de separation d'isomeres optiques des derives de la dihydro-1,4 pyridine.

Publications (1)

Publication Number Publication Date
ES2057455T3 true ES2057455T3 (es) 1994-10-16

Family

ID=9385673

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90400096T Expired - Lifetime ES2057455T3 (es) 1989-09-20 1990-01-15 Procedimiento de preparacion de isomeros opticos de los derivados de la 1,4-dihidro-piridina.

Country Status (14)

Country Link
EP (1) EP0419297B1 (es)
JP (1) JPH03112965A (es)
AT (1) ATE106870T1 (es)
AU (1) AU618444B2 (es)
CA (1) CA2007718A1 (es)
DE (1) DE69009642T2 (es)
DK (1) DK0419297T3 (es)
ES (1) ES2057455T3 (es)
FR (1) FR2652083B1 (es)
IE (1) IE63293B1 (es)
NZ (1) NZ232089A (es)
OA (1) OA09436A (es)
PT (1) PT92859B (es)
ZA (1) ZA90231B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686879B1 (fr) * 1992-02-05 1994-03-18 Adir Cie Nouveaux composes de 1,4-dihydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
FR2602231B1 (fr) * 1986-08-04 1988-10-28 Adir Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2649395B1 (fr) * 1989-07-04 1992-11-06 Adir Nouveau derive de la dihydro-1,4 pyridine denomme (-) Ÿi1Ÿ(((amino-2 ethoxy)-2 ethoxy) methylŸi1Ÿ) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent

Also Published As

Publication number Publication date
EP0419297B1 (fr) 1994-06-08
OA09436A (fr) 1992-10-15
PT92859A (pt) 1990-07-31
AU618444B2 (en) 1991-12-19
DE69009642D1 (de) 1994-07-14
IE900028A1 (en) 1991-03-27
ZA90231B (en) 1990-11-28
EP0419297A1 (fr) 1991-03-27
IE63293B1 (en) 1995-04-05
PT92859B (pt) 1995-12-29
NZ232089A (en) 1991-09-25
AU4792690A (en) 1991-03-28
DE69009642T2 (de) 1994-10-27
FR2652083A1 (fr) 1991-03-22
DK0419297T3 (da) 1994-10-31
JPH03112965A (ja) 1991-05-14
CA2007718A1 (fr) 1991-03-20
FR2652083B1 (fr) 1992-01-24
ATE106870T1 (de) 1994-06-15

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