ES515573A0 - Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo. - Google Patents
Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo.Info
- Publication number
- ES515573A0 ES515573A0 ES515573A ES515573A ES515573A0 ES 515573 A0 ES515573 A0 ES 515573A0 ES 515573 A ES515573 A ES 515573A ES 515573 A ES515573 A ES 515573A ES 515573 A0 ES515573 A0 ES 515573A0
- Authority
- ES
- Spain
- Prior art keywords
- halogenovinyl
- beta
- furanosil
- uracilo
- arabino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56142045A JPS5843993A (ja) | 1981-09-09 | 1981-09-09 | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8308570A1 ES8308570A1 (es) | 1983-09-16 |
ES515573A0 true ES515573A0 (es) | 1983-09-16 |
Family
ID=15306105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515573A Granted ES515573A0 (es) | 1981-09-09 | 1982-09-08 | Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4542210A (es) |
EP (1) | EP0074101B1 (es) |
JP (1) | JPS5843993A (es) |
KR (1) | KR890000762B1 (es) |
AT (1) | ATE12503T1 (es) |
AU (1) | AU552353B2 (es) |
CA (1) | CA1204107A (es) |
DE (1) | DE3262887D1 (es) |
ES (1) | ES515573A0 (es) |
GB (1) | GB2108964B (es) |
MY (1) | MY8700826A (es) |
SG (1) | SG81787G (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
JPS58225097A (ja) * | 1982-06-23 | 1983-12-27 | Yamasa Shoyu Co Ltd | ヌクレオシド5′−アルキルもしくはアルケニルりん酸 |
NZ205619A (en) * | 1982-09-17 | 1987-09-30 | Glaxo Group Ltd | 5-halovinyl-2'-deoxyuridines and pharmaceutical compositions |
US4658044A (en) * | 1983-09-16 | 1987-04-14 | Glaxo Group Limited | Intermediates for uracil derivatives |
ZA85578B (en) * | 1985-01-24 | 1985-07-22 | Neopharmed S.P.A. | Acylated derivatives of cytidine-diphosphate-choline,process for their preparation and their therapeutic use |
GB8912972D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Therapeutic nucleosides |
US5446031A (en) * | 1991-04-24 | 1995-08-29 | Yamasa Shuyu Kabushiki Kaisha | 1-β-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivatives |
AU645422B2 (en) * | 1991-04-24 | 1994-01-13 | Yamasa Shoyu Kabushiki Kaisha | 1-beta-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)-uracil derivative |
JP2001512830A (ja) * | 1997-08-08 | 2001-08-28 | ニューバイオティックス インコーポレイテッド | 生物療法耐性および化学療法耐性を克服するための方法および組成物 |
US7462605B2 (en) * | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
IL137164A0 (en) | 1998-01-23 | 2001-07-24 | Newbiotics Inc | Enzyme catalyzed therapeutic agents |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US6683061B1 (en) * | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
BR0012676A (pt) | 1999-07-22 | 2003-07-01 | Newbiotics Inc | Métodos para tratamento de tumores resistentes a terapia |
AU2002241911B9 (en) * | 2001-01-19 | 2007-01-25 | Celmed Oncology (Usa), Inc. | Methods to treat autoimmune and inflammatory conditions |
US7211570B2 (en) * | 2001-12-20 | 2007-05-01 | Pharmasset, Inc. | Treatment of EBV and KHSV infection |
JP4964473B2 (ja) * | 2006-02-10 | 2012-06-27 | アリジェン製薬株式会社 | ピリミジンヌクレオシド誘導体及びその塩 |
WO2008099492A1 (ja) * | 2007-02-15 | 2008-08-21 | Arigen Pharmaceuticals, Inc. | ピリミジンヌクレオシド誘導体及びその塩 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1487712A (fr) * | 1965-07-27 | 1967-07-07 | Takeda Chemical Industries Ltd | Procédé de production du 5'-ribonucléotide |
US3382232A (en) * | 1965-08-26 | 1968-05-07 | Takeda Chemical Industries Ltd | Method for the production of 5'-ribonucleotide |
FR5616M (es) * | 1966-07-29 | 1968-01-15 | ||
EP0015584A3 (de) * | 1979-03-12 | 1980-12-10 | Kailash Kumar Dr. Prof. Gauri | Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
GB2060604B (en) * | 1979-10-03 | 1983-11-23 | Univ Birmingham And Stichting | E15-(2-halogenovinyl)-2'-deoxycytidines |
JPS5687599A (en) * | 1979-12-19 | 1981-07-16 | Yamasa Shoyu Co Ltd | E 55 22halogenovinyl arabinofuranosyluracil and its preparation |
JPS5714598A (en) * | 1980-06-30 | 1982-01-25 | Yamasa Shoyu Co Ltd | 5-substituted-1-beta-d-arabinofuranosyluracil derivative and its preparation |
US4383990A (en) * | 1980-10-01 | 1983-05-17 | Beecham Group Limited | Antiviral agents, their preparation and use |
JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
-
1981
- 1981-09-09 JP JP56142045A patent/JPS5843993A/ja active Granted
-
1982
- 1982-09-03 DE DE8282108163T patent/DE3262887D1/de not_active Expired
- 1982-09-03 AU AU87996/82A patent/AU552353B2/en not_active Ceased
- 1982-09-03 AT AT82108163T patent/ATE12503T1/de not_active IP Right Cessation
- 1982-09-03 KR KR8203969A patent/KR890000762B1/ko active
- 1982-09-03 US US06/414,824 patent/US4542210A/en not_active Expired - Fee Related
- 1982-09-03 EP EP82108163A patent/EP0074101B1/en not_active Expired
- 1982-09-08 CA CA000411003A patent/CA1204107A/en not_active Expired
- 1982-09-08 GB GB08225547A patent/GB2108964B/en not_active Expired
- 1982-09-08 ES ES515573A patent/ES515573A0/es active Granted
-
1987
- 1987-10-09 SG SG817/87A patent/SG81787G/en unknown
- 1987-12-30 MY MY826/87A patent/MY8700826A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE3262887D1 (en) | 1985-05-09 |
EP0074101A1 (en) | 1983-03-16 |
US4542210A (en) | 1985-09-17 |
MY8700826A (en) | 1987-12-31 |
EP0074101B1 (en) | 1985-04-03 |
AU552353B2 (en) | 1986-05-29 |
ATE12503T1 (de) | 1985-04-15 |
AU8799682A (en) | 1983-03-17 |
GB2108964A (en) | 1983-05-25 |
JPS637559B2 (es) | 1988-02-17 |
KR840001589A (ko) | 1984-05-07 |
KR890000762B1 (ko) | 1989-04-05 |
CA1204107A (en) | 1986-05-06 |
SG81787G (en) | 1988-04-15 |
ES8308570A1 (es) | 1983-09-16 |
GB2108964B (en) | 1985-04-11 |
JPS5843993A (ja) | 1983-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20040601 |