ES515573A0 - Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo. - Google Patents
Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo.Info
- Publication number
- ES515573A0 ES515573A0 ES515573A ES515573A ES515573A0 ES 515573 A0 ES515573 A0 ES 515573A0 ES 515573 A ES515573 A ES 515573A ES 515573 A ES515573 A ES 515573A ES 515573 A0 ES515573 A0 ES 515573A0
- Authority
- ES
- Spain
- Prior art keywords
- halogenovinyl
- beta
- furanosil
- uracilo
- arabino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56142045A JPS5843993A (ja) | 1981-09-09 | 1981-09-09 | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8308570A1 ES8308570A1 (es) | 1983-09-16 |
| ES515573A0 true ES515573A0 (es) | 1983-09-16 |
Family
ID=15306105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515573A Granted ES515573A0 (es) | 1981-09-09 | 1982-09-08 | Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4542210A (OSRAM) |
| EP (1) | EP0074101B1 (OSRAM) |
| JP (1) | JPS5843993A (OSRAM) |
| KR (1) | KR890000762B1 (OSRAM) |
| AT (1) | ATE12503T1 (OSRAM) |
| AU (1) | AU552353B2 (OSRAM) |
| CA (1) | CA1204107A (OSRAM) |
| DE (1) | DE3262887D1 (OSRAM) |
| ES (1) | ES515573A0 (OSRAM) |
| GB (1) | GB2108964B (OSRAM) |
| MY (1) | MY8700826A (OSRAM) |
| SG (1) | SG81787G (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
| JPS58225097A (ja) * | 1982-06-23 | 1983-12-27 | Yamasa Shoyu Co Ltd | ヌクレオシド5′−アルキルもしくはアルケニルりん酸 |
| NZ205619A (en) * | 1982-09-17 | 1987-09-30 | Glaxo Group Ltd | 5-halovinyl-2'-deoxyuridines and pharmaceutical compositions |
| US4658044A (en) * | 1983-09-16 | 1987-04-14 | Glaxo Group Limited | Intermediates for uracil derivatives |
| ZA85578B (en) * | 1985-01-24 | 1985-07-22 | Neopharmed S.P.A. | Acylated derivatives of cytidine-diphosphate-choline,process for their preparation and their therapeutic use |
| GB8912972D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Therapeutic nucleosides |
| WO1992019638A1 (en) * | 1991-04-24 | 1992-11-12 | Yamasa Shoyu Kabushiki Kaisha | 1-β-D-ARABINOFURANOSYL-(E)-5-(2-HALOGENOVINYL)-URACIL DERIVATIVE |
| US5446031A (en) * | 1991-04-24 | 1995-08-29 | Yamasa Shuyu Kabushiki Kaisha | 1-β-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivatives |
| CA2298681C (en) | 1997-08-08 | 2008-07-08 | Newbiotics, Inc. | Methods and compositions for overcoming resistance to biologic and chemotherapy |
| EP1045897B1 (en) | 1998-01-23 | 2002-01-30 | Newbiotics Inc. | Enzyme catalyzed therapeutic agents |
| US7462605B2 (en) * | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
| US6653318B1 (en) * | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
| CN1391486A (zh) | 1999-07-22 | 2003-01-15 | 新生物公司 | 治疗对治疗有抗性的肿瘤的方法 |
| US6683061B1 (en) * | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
| CA2441350A1 (en) * | 2001-01-19 | 2002-07-25 | Newbiotics, Inc. | Methods to treat autoimmune and inflammatory conditions |
| WO2003053360A2 (en) * | 2001-12-20 | 2003-07-03 | Pharmassett Ltd. | Treatment of ebv and khsv infection and associated abnormal cellular proliferation |
| JP4964473B2 (ja) * | 2006-02-10 | 2012-06-27 | アリジェン製薬株式会社 | ピリミジンヌクレオシド誘導体及びその塩 |
| US8076302B2 (en) | 2007-02-15 | 2011-12-13 | Arigen Pharmaceuticals, Inc. | Pyrimidine nucleoside derivatives and salts thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE684554A (OSRAM) * | 1965-07-27 | 1967-01-03 | ||
| US3382232A (en) * | 1965-08-26 | 1968-05-07 | Takeda Chemical Industries Ltd | Method for the production of 5'-ribonucleotide |
| FR5616M (OSRAM) * | 1966-07-29 | 1968-01-15 | ||
| EP0015584A3 (de) * | 1979-03-12 | 1980-12-10 | Kailash Kumar Dr. Prof. Gauri | Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel |
| US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
| US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
| GB2060604B (en) * | 1979-10-03 | 1983-11-23 | Univ Birmingham And Stichting | E15-(2-halogenovinyl)-2'-deoxycytidines |
| JPS5687599A (en) * | 1979-12-19 | 1981-07-16 | Yamasa Shoyu Co Ltd | E 55 22halogenovinyl arabinofuranosyluracil and its preparation |
| JPS5714598A (en) * | 1980-06-30 | 1982-01-25 | Yamasa Shoyu Co Ltd | 5-substituted-1-beta-d-arabinofuranosyluracil derivative and its preparation |
| US4383990A (en) * | 1980-10-01 | 1983-05-17 | Beecham Group Limited | Antiviral agents, their preparation and use |
| JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
-
1981
- 1981-09-09 JP JP56142045A patent/JPS5843993A/ja active Granted
-
1982
- 1982-09-03 EP EP82108163A patent/EP0074101B1/en not_active Expired
- 1982-09-03 US US06/414,824 patent/US4542210A/en not_active Expired - Fee Related
- 1982-09-03 KR KR8203969A patent/KR890000762B1/ko not_active Expired
- 1982-09-03 AU AU87996/82A patent/AU552353B2/en not_active Ceased
- 1982-09-03 DE DE8282108163T patent/DE3262887D1/de not_active Expired
- 1982-09-03 AT AT82108163T patent/ATE12503T1/de not_active IP Right Cessation
- 1982-09-08 GB GB08225547A patent/GB2108964B/en not_active Expired
- 1982-09-08 CA CA000411003A patent/CA1204107A/en not_active Expired
- 1982-09-08 ES ES515573A patent/ES515573A0/es active Granted
-
1987
- 1987-10-09 SG SG817/87A patent/SG81787G/en unknown
- 1987-12-30 MY MY826/87A patent/MY8700826A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2108964A (en) | 1983-05-25 |
| AU8799682A (en) | 1983-03-17 |
| DE3262887D1 (en) | 1985-05-09 |
| GB2108964B (en) | 1985-04-11 |
| KR840001589A (ko) | 1984-05-07 |
| KR890000762B1 (ko) | 1989-04-05 |
| JPS637559B2 (OSRAM) | 1988-02-17 |
| EP0074101B1 (en) | 1985-04-03 |
| EP0074101A1 (en) | 1983-03-16 |
| JPS5843993A (ja) | 1983-03-14 |
| ES8308570A1 (es) | 1983-09-16 |
| AU552353B2 (en) | 1986-05-29 |
| SG81787G (en) | 1988-04-15 |
| MY8700826A (en) | 1987-12-31 |
| CA1204107A (en) | 1986-05-06 |
| ATE12503T1 (de) | 1985-04-15 |
| US4542210A (en) | 1985-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES515573A0 (es) | Un procedimiento para producir 5'-fosfato de 1, beta d-arabino-furanosil-(e)-5-(2-halogenovinil) uracilo. | |
| IL71664A0 (en) | Fluoroalkoxy compounds,process for their preparation,and pharmaceutical composition containing the same | |
| RO77559A (ro) | Procedeu de preparare a eritro-9-(2-hidroxi-3-alchil)hidroxantinei | |
| NO823836L (no) | Fremgangsmaate ved fremstilling av antifibrinolytisk aktive forbindelser. | |
| DK357585A (da) | Fremgangsmaade til fremstilling af 2'-deoxyadenosinforbindelser | |
| ES515081A0 (es) | "procedimiento para la preparacion de derivados de 6-metilprednisolona". | |
| DK281482A (da) | Fremgangsmaade til fremstilling af 2-aryl-3,4-diazabicyclo(4.n.o)alken-(2)-on-5-forbindelser | |
| AU542509B2 (en) | Phosphoric acids and their derivatives | |
| ES498508A0 (es) | Procedimiento para la preparacion de 2-halo piridinas | |
| MX155561A (es) | Procedimiento para la obtencion de derivados de fenetanolamina | |
| ES2068663T3 (es) | Procedimiento para la preparacion de compuestos de piridina sustituidos con halogenosulfonilo. | |
| ES540260A0 (es) | Procedimiento para preparar derivados de 2-alcoxiaminosulfo-nilbencenosulfonilurea | |
| DE3261606D1 (en) | Novel quinolinecarboxylic acid derivative, process for production thereof, and antibacterial agent containing said compound as active ingredient | |
| DE3060236D1 (en) | Thiazole derivatives, their preparation and medicaments containing them | |
| FR2366298A1 (fr) | Procede de preparation de derives de rifamycine p et q | |
| BR8200443A (pt) | Processo para a preparacao de compostos de 2-piridiloxi-acetanilida,composicoes herbicidas,processo para o combate de ervas daninhas e para a preparacao de composicoes herbicidas | |
| FR2434801A1 (fr) | Procede de preparation d'hexamethylene bis-(dicyanodiamide) | |
| MX155296A (es) | Procedimiento para preparar derivados de tiazol | |
| IL61784A (en) | 2-(1-methoxy-2-chloroethoxy)-phenyl-n-methyl-n-trimethyl-silyl-carbamate,its preparation and pesticidal compositions containing it | |
| JPS57156440A (en) | Novel derivatives of 4-methyl-3-formylpentanoic acid, manufacture and use for manufacturing cyclic derivatives | |
| ES516405A0 (es) | "un procedimiento para la preparacion de compuestos de isocianuro-triorganoestano". | |
| ES477248A1 (es) | Un procedimiento para la obtencion de 6-aril-1,2,2-trimetil-4-metilenpiperidinas. | |
| SE8300686D0 (sv) | Herbicidal compositions | |
| ES459649A1 (es) | Un procedimiento para la produccion de un derivado de diaza-bicicloalcano. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20040601 |