ES486023A1 - Un procedimiento para la preparacion de antibioticos de ce- falosporina - Google Patents

Un procedimiento para la preparacion de antibioticos de ce- falosporina

Info

Publication number
ES486023A1
ES486023A1 ES486023A ES486023A ES486023A1 ES 486023 A1 ES486023 A1 ES 486023A1 ES 486023 A ES486023 A ES 486023A ES 486023 A ES486023 A ES 486023A ES 486023 A1 ES486023 A1 ES 486023A1
Authority
ES
Spain
Prior art keywords
antibiotics
activity against
high activity
cephalosporin antibiotics
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486023A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES486023A1 publication Critical patent/ES486023A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compuestos de cefalosporina, que poseen valiosas propiedades anfibióticas. Los antibióticos de cefalosporina son ampliamente utilizados en el tratamiento de enfermedades provocadas por bacterias patógenas en los seres humanos y animales, y son especialmente útiles para el tratamiento de enfermedades provocadas por bacterias que son resistentes a otros antibióticos, tales como compuestos de penicilina, y en el tratamiento de pacientes sensibles a la penicilina. En muchos casos, es deseable emplear un antibiótico de cefalosporina que muestre actividad contra microorganismos tanto gram positivos como gram negativos, y una importante cantidad de investigaciones ha sido encaminada al desarrollo de diversos tipos de antibioticos de cefalosporina de amplio espectro.
ES486023A 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina Expired ES486023A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7844873 1978-11-17

Publications (1)

Publication Number Publication Date
ES486023A1 true ES486023A1 (es) 1980-09-01

Family

ID=10501112

Family Applications (3)

Application Number Title Priority Date Filing Date
ES486026A Expired ES486026A1 (es) 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES486022A Expired ES8102139A1 (es) 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES486023A Expired ES486023A1 (es) 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES486026A Expired ES486026A1 (es) 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES486022A Expired ES8102139A1 (es) 1978-11-17 1979-11-16 Un procedimiento para la preparacion de antibioticos de ce- falosporina

Country Status (17)

Country Link
US (1) US4504477A (es)
JP (1) JPS5589289A (es)
AT (1) AT369377B (es)
AU (1) AU531801B2 (es)
BE (1) BE880068A (es)
CA (1) CA1131216A (es)
CH (1) CH649557A5 (es)
DE (1) DE2946415A1 (es)
DK (1) DK487979A (es)
ES (3) ES486026A1 (es)
FR (1) FR2441629A1 (es)
IE (1) IE49211B1 (es)
IT (1) IT1207008B (es)
NL (1) NL7908390A (es)
NZ (1) NZ192142A (es)
SE (1) SE7909501L (es)
ZA (1) ZA796195B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR229882A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
ZA823722B (en) * 1981-06-22 1983-03-30 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
FR2516515A1 (fr) * 1981-11-16 1983-05-20 Sanofi Sa Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
KR920004820B1 (ko) * 1984-02-23 1992-06-18 메이지제과 주식회사 새로운 세팔로스포린 유도체의 제조방법
US4645769A (en) * 1985-03-01 1987-02-24 Merck & Co., Inc. 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
JPH064645B2 (ja) * 1985-11-27 1994-01-19 明治製菓株式会社 新規セフアロスポリン誘導体およびそれを含む抗菌剤
FR2833265B1 (fr) * 2001-12-06 2006-02-10 Rhodia Chimie Sa Procede d'obtention de monoorganoxysilane polysulfures

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144392A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
PT70995B (en) * 1979-03-22 1981-06-25 Glaxo Group Ltd Cephalosporin antibiotics
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
US4394503A (en) * 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
IE792208L (en) 1980-05-17
CA1131216A (en) 1982-09-07
NZ192142A (en) 1982-12-21
IT1207008B (it) 1989-05-17
NL7908390A (nl) 1980-05-20
ZA796195B (en) 1980-11-26
SE7909501L (sv) 1980-05-18
JPS5589289A (en) 1980-07-05
IE49211B1 (en) 1985-08-21
DE2946415A1 (de) 1980-05-29
ATA732879A (de) 1982-05-15
ES486022A0 (es) 1980-12-16
AT369377B (de) 1982-12-27
AU531801B2 (en) 1983-09-08
FR2441629B1 (es) 1983-04-01
ES8102139A1 (es) 1980-12-16
BE880068A (fr) 1980-05-16
AU5291979A (en) 1980-05-22
IT7950842A0 (it) 1979-11-16
CH649557A5 (de) 1985-05-31
ES486026A1 (es) 1980-09-01
FR2441629A1 (fr) 1980-06-13
US4504477A (en) 1985-03-12
DK487979A (da) 1980-05-18

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601