ES478070A1 - Un procedimiento de preparacion de derivados bencilidenicos. - Google Patents

Un procedimiento de preparacion de derivados bencilidenicos.

Info

Publication number
ES478070A1
ES478070A1 ES478070A ES478070A ES478070A1 ES 478070 A1 ES478070 A1 ES 478070A1 ES 478070 A ES478070 A ES 478070A ES 478070 A ES478070 A ES 478070A ES 478070 A1 ES478070 A1 ES 478070A1
Authority
ES
Spain
Prior art keywords
alkyl
compounds
ch3o
exception
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478070A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7805578A external-priority patent/FR2418222A2/fr
Priority claimed from FR7820940A external-priority patent/FR2430936A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES478070A1 publication Critical patent/ES478070A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento de preparación de derivados bencilidénicos que responden a la fórmula (I) **(Fórmula)** en la cual X1, X2, X3 y X4 representan, cada uno, independientemente el uno del otro, un átomo de hidrógeno o de halógeno, un radical CH3, CH3O, NO2, CF3, C(CH3)3 ó CH3CONH; n representa un número entero que está comprendido entre 1 y 10; R es un radical OH, OM (M= metal alcalino), NH2, NH- cicloalcohilo, NH-fenilo, NH-bencilo, NH-alcohilo, N- (alcohilo)2, N-(alcohil)-(bencilo), y R'' representa un átomo de hidrógeno o un alcohilo, teniendo los alcohilos de 1 a 4 átomos de carbono, con la excepción de los compuestos en los que R'' = H cuando X1, X2 y X3 son, cada uno, independientemente el uno del otro, H, Hal, CH3, CH3O y X4 = H y del compuesto para el cual R'' = H, X1 - X3 = X4 = H, X2 = C1-5, n = 1 y R = OH.
ES478070A 1978-02-27 1979-02-26 Un procedimiento de preparacion de derivados bencilidenicos. Expired ES478070A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7805578A FR2418222A2 (fr) 1975-08-01 1978-02-27 Procede de preparation de derives benzylideniques
FR7820940A FR2430936A1 (fr) 1978-07-13 1978-07-13 Derives benzylideniques, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES478070A1 true ES478070A1 (es) 1979-07-01

Family

ID=26220461

Family Applications (1)

Application Number Title Priority Date Filing Date
ES478070A Expired ES478070A1 (es) 1978-02-27 1979-02-26 Un procedimiento de preparacion de derivados bencilidenicos.

Country Status (20)

Country Link
JP (1) JPS54125644A (es)
AT (1) AT365564B (es)
AU (1) AU520618B2 (es)
BE (1) BE874488A (es)
CA (1) CA1119613A (es)
CH (1) CH637112A5 (es)
DE (1) DE2907379A1 (es)
DK (1) DK82079A (es)
ES (1) ES478070A1 (es)
FI (1) FI790656A (es)
GB (1) GB2021559B (es)
GR (1) GR66971B (es)
IE (1) IE47930B1 (es)
IT (1) IT1113010B (es)
LU (1) LU80974A1 (es)
NL (1) NL7901474A (es)
NO (1) NO790646L (es)
NZ (1) NZ189769A (es)
PT (1) PT69288A (es)
SE (1) SE7901706L (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0047516B1 (en) * 1980-09-04 1984-01-04 Toray Industries, Inc. Propylamine derivative and process of manufacturing the same
JPS5746951A (en) * 1980-09-04 1982-03-17 Toray Ind Inc Production of 2-amino-4-cyanobutyric derivative
FR2536746A1 (fr) * 1982-11-29 1984-06-01 Synthelabo Derives benzylideniques alkyles, leur preparation et leur application en therapeutique
FR2544308B1 (fr) * 1983-04-14 1985-06-14 Synthelabo Ethines substituees, leur preparation et leur application en therapeutique
EP0367671B1 (en) * 1988-11-03 1993-07-28 Fournier Industrie Et Sante Novel beta-d-phenylthioxylosides, their method of preparation and their use as pharmaceuticals
WO1991007380A1 (en) * 1989-11-08 1991-05-30 Dunlena Pty. Ltd. Arthropodicides
JP2005232103A (ja) * 2004-02-20 2005-09-02 Nagase & Co Ltd 光学活性なビシナルジアミンおよびその製造方法

Also Published As

Publication number Publication date
NZ189769A (en) 1981-07-13
CH637112A5 (fr) 1983-07-15
IT7920543A0 (it) 1979-02-26
AU4460279A (en) 1979-09-06
JPS54125644A (en) 1979-09-29
AT365564B (de) 1982-01-25
CA1119613A (en) 1982-03-09
GR66971B (es) 1981-05-15
ATA149179A (de) 1981-06-15
GB2021559A (en) 1979-12-05
GB2021559B (en) 1982-07-07
AU520618B2 (en) 1982-02-11
IT1113010B (it) 1986-01-20
BE874488A (fr) 1979-08-27
DK82079A (da) 1979-08-28
NO790646L (no) 1979-08-28
IE47930B1 (en) 1984-07-25
FI790656A (fi) 1979-08-28
SE7901706L (sv) 1979-08-28
DE2907379A1 (de) 1979-09-06
LU80974A1 (fr) 1980-09-24
IE790556L (en) 1979-08-27
PT69288A (fr) 1979-03-01
NL7901474A (nl) 1979-08-29

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