ES476110A1 - Procedimiento para la acilacion de derivados de 6-aminopenamy de 7-aminocefem. - Google Patents
Procedimiento para la acilacion de derivados de 6-aminopenamy de 7-aminocefem.Info
- Publication number
- ES476110A1 ES476110A1 ES476110A ES476110A ES476110A1 ES 476110 A1 ES476110 A1 ES 476110A1 ES 476110 A ES476110 A ES 476110A ES 476110 A ES476110 A ES 476110A ES 476110 A1 ES476110 A1 ES 476110A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl moiety
- hydroxy
- amino
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QITDACOZCQXYQY-BAFYGKSASA-N (6r)-7-amino-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical class S1CC=CN2C(=O)C(N)[C@H]21 QITDACOZCQXYQY-BAFYGKSASA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 10
- -1 hydroxy, amino Chemical group 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
- ASOKPJOREAFHNY-UHFFFAOYSA-N 1-Hydroxybenzotriazole Chemical compound C1=CC=C2N(O)N=NC2=C1 ASOKPJOREAFHNY-UHFFFAOYSA-N 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000006323 alkenyl amino group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004471 alkyl aminosulfonyl group Chemical group 0.000 abstract 1
- 125000005336 allyloxy group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004472 dialkylaminosulfonyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772758000 DE2758000A1 (de) | 1977-12-24 | 1977-12-24 | Verfahren zur herstellung von penicillinen und cephalosporinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES476110A1 true ES476110A1 (es) | 1979-04-16 |
Family
ID=6027278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES476110A Expired ES476110A1 (es) | 1977-12-24 | 1978-12-19 | Procedimiento para la acilacion de derivados de 6-aminopenamy de 7-aminocefem. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0002774B1 (en, 2012) |
| JP (1) | JPS5495593A (en, 2012) |
| AT (1) | AT370417B (en, 2012) |
| AU (1) | AU526890B2 (en, 2012) |
| CA (1) | CA1106358A (en, 2012) |
| DE (2) | DE2758000A1 (en, 2012) |
| DK (1) | DK579878A (en, 2012) |
| ES (1) | ES476110A1 (en, 2012) |
| IE (1) | IE48101B1 (en, 2012) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0037380B1 (en) * | 1980-03-28 | 1984-09-12 | BIOCHEMIE Gesellschaft m.b.H. | New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production |
| DE3037997A1 (de) * | 1980-10-08 | 1982-05-13 | Bayer Ag | (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel |
| DK165118C (da) * | 1980-11-22 | 1993-03-01 | Gema Sa | Fremgangsmaade til fremstilling af oploesninger af 7-aminocephalosporansyrer |
| ES8106907A1 (es) * | 1980-11-22 | 1981-10-01 | Gema Sa | Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos |
| US4681877A (en) * | 1982-12-24 | 1987-07-21 | Kureha Kagaku Kogyo Kabushiki Kaisha | Pivaloyloxymethyl 7-β-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-(2-amino-1,3-thiadiazolyl-5-thiomethyl)-3-cepheme-4-carboxylate and pharmaceutical composition containing the same |
| US4914091A (en) * | 1984-04-02 | 1990-04-03 | American Cyanamid Company | Esters of cephalosporin derivitives |
| KR870001332B1 (ko) * | 1984-09-27 | 1987-07-18 | 한미약품공업 주식회사 | 세펨 유도체의 간단한 제조방법 |
| GR890100706A (el) * | 1989-10-31 | 1992-03-20 | Han Mi Pharma Ind Co Ltd | Μέ?οδος παρασκευής παραγώγων κεφέμης. |
| KR950014571B1 (ko) * | 1991-11-18 | 1995-12-08 | 제일제당주식회사 | 세펨 유도체의 제조방법 |
| KR100197788B1 (ko) * | 1995-06-30 | 1999-06-15 | 김충환 | 세펨 유도체의 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1668723A1 (de) * | 1966-09-16 | 1971-04-08 | Toyo Jozo Kk | Verfahren zum Herstellen von Verbindungen mit Saeureamid-Bindung |
| US4073780A (en) * | 1976-06-03 | 1978-02-14 | Pfizer Inc. | 4-Pyridylformimidoylglycyl-D-phenylglycine |
| US4319028A (en) * | 1976-08-26 | 1982-03-09 | Eli Lilly And Company | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins |
-
1977
- 1977-12-24 DE DE19772758000 patent/DE2758000A1/de not_active Withdrawn
-
1978
- 1978-12-18 EP EP78101749A patent/EP0002774B1/de not_active Expired
- 1978-12-18 DE DE7878101749T patent/DE2861126D1/de not_active Expired
- 1978-12-19 ES ES476110A patent/ES476110A1/es not_active Expired
- 1978-12-21 AU AU42785/78A patent/AU526890B2/en not_active Expired
- 1978-12-22 AT AT0924078A patent/AT370417B/de not_active IP Right Cessation
- 1978-12-22 CA CA318,498A patent/CA1106358A/en not_active Expired
- 1978-12-22 DK DK579878A patent/DK579878A/da not_active Application Discontinuation
- 1978-12-23 JP JP15817378A patent/JPS5495593A/ja active Granted
- 1978-12-24 IE IE2545/78A patent/IE48101B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2758000A1 (de) | 1979-07-05 |
| DE2861126D1 (en) | 1981-12-10 |
| IE48101B1 (en) | 1984-10-03 |
| EP0002774A1 (de) | 1979-07-11 |
| ATA924078A (de) | 1982-08-15 |
| JPS6337112B2 (en, 2012) | 1988-07-22 |
| AU526890B2 (en) | 1983-02-03 |
| AT370417B (de) | 1983-03-25 |
| IE782545L (en) | 1979-06-24 |
| CA1106358A (en) | 1981-08-04 |
| DK579878A (da) | 1979-06-25 |
| AU4278578A (en) | 1979-06-28 |
| EP0002774B1 (de) | 1981-09-23 |
| JPS5495593A (en) | 1979-07-28 |
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