ES468967A1 - Un procedimiento para la preparacion de d-homoesteroides - Google Patents

Un procedimiento para la preparacion de d-homoesteroides

Info

Publication number
ES468967A1
ES468967A1 ES468967A ES468967A ES468967A1 ES 468967 A1 ES468967 A1 ES 468967A1 ES 468967 A ES468967 A ES 468967A ES 468967 A ES468967 A ES 468967A ES 468967 A1 ES468967 A1 ES 468967A1
Authority
ES
Spain
Prior art keywords
homopregnanes
aroyloxy
fluoro
chloro
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468967A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU77173A external-priority patent/LU77173A1/xx
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES468967A1 publication Critical patent/ES468967A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la preparación de D-homoesteroides de la fórmula general **(Fórmula)** en donde R6 representa un átomo de hidrógeno, cloro o flúor o un grupo metílico X representa un grupo beta-hidroximetilénico o carbonílico, R17a representa un grupo hidroxílico o aciloxílico y R21 representa un átomo de hidrógeno, cloro o flúor o un grupo hidroxílico o aciloxilico o un radical de sulfato o fosfato, y la línea de trazos en la posición 1,2 denota un enlace carbono-carbono opcional, y sus sales.
ES468967A 1977-04-21 1978-04-20 Un procedimiento para la preparacion de d-homoesteroides Expired ES468967A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77173A LU77173A1 (es) 1977-04-21 1977-04-21
CH13978A CH632280A5 (en) 1977-04-21 1978-01-06 D-Homosteroids

Publications (1)

Publication Number Publication Date
ES468967A1 true ES468967A1 (es) 1979-09-16

Family

ID=25683635

Family Applications (1)

Application Number Title Priority Date Filing Date
ES468967A Expired ES468967A1 (es) 1977-04-21 1978-04-20 Un procedimiento para la preparacion de d-homoesteroides

Country Status (23)

Country Link
US (1) US4131655A (es)
JP (1) JPS53132553A (es)
AR (1) AR220127A1 (es)
AT (1) AT358748B (es)
AU (1) AU515487B2 (es)
CA (1) CA1114364A (es)
DE (1) DE2817081A1 (es)
DK (1) DK158678A (es)
ES (1) ES468967A1 (es)
FI (1) FI62317C (es)
FR (1) FR2387997A1 (es)
GB (1) GB1587032A (es)
GR (1) GR72714B (es)
HU (1) HU179486B (es)
IE (1) IE46775B1 (es)
IL (1) IL54508A (es)
IT (1) IT1094923B (es)
NL (1) NL7802905A (es)
NO (1) NO147275C (es)
NZ (1) NZ186988A (es)
PH (1) PH15961A (es)
PT (1) PT67927B (es)
SE (1) SE7804552L (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2950026C2 (de) * 1979-12-10 1982-05-19 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 11-Ketosteroiden
JPS60161914A (ja) * 1984-02-02 1985-08-23 Green Cross Corp:The ステロイド脂肪酸エステル含有直腸投与製剤
DE3409554A1 (de) * 1984-03-13 1985-09-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methyl-d-homo-kortikoide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
US4036874A (en) * 1972-03-29 1977-07-19 Hoffmann-La Roche Inc. D-homopregnanes
GB1440064A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd Delta8-9- steroids of the pregnane series
NO140672C (no) * 1973-03-28 1979-10-17 Hoffmann La Roche Analogifremgangsmaate ved fremstilling av nye anti-inflammatorisk virksomme steroider
DE2448662C2 (de) * 1974-10-09 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen 6α-Fluor-16α-methyl-1,4,8-pregnatrien-3,20-dion-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
IL51468A (en) * 1976-02-23 1981-01-30 Sparamedica Ag 17 -hydroxy- -d-homosteroid derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB1587032A (en) 1981-03-25
IL54508A0 (en) 1978-07-31
IE46775B1 (en) 1983-09-21
FR2387997A1 (fr) 1978-11-17
DK158678A (da) 1978-10-22
PT67927B (en) 1980-04-07
US4131655A (en) 1978-12-26
GR72714B (es) 1983-12-01
SE7804552L (sv) 1978-10-22
FI62317B (fi) 1982-08-31
CA1114364A (en) 1981-12-15
NO147275B (no) 1982-11-29
DE2817081A1 (de) 1978-11-09
FI781055A (fi) 1978-10-22
NO147275C (no) 1983-03-16
IT1094923B (it) 1985-08-10
FR2387997B1 (es) 1980-01-18
FI62317C (fi) 1982-12-10
AR220127A1 (es) 1980-10-15
IL54508A (en) 1982-03-31
NZ186988A (en) 1980-05-27
NL7802905A (nl) 1978-10-24
AU3512378A (en) 1979-10-18
JPS53132553A (en) 1978-11-18
AT358748B (de) 1980-09-25
PT67927A (en) 1978-05-01
AU515487B2 (en) 1981-04-09
IT7822628A0 (it) 1978-04-21
HU179486B (en) 1982-10-28
IE780750L (en) 1978-10-21
NO781390L (no) 1978-10-24
PH15961A (en) 1983-05-04
ATA281178A (de) 1980-02-15

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