ES467750A3 - Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES467750A3
ES467750A3 ES0467750A ES467750A ES467750A3 ES 467750 A3 ES467750 A3 ES 467750A3 ES 0467750 A ES0467750 A ES 0467750A ES 467750 A ES467750 A ES 467750A ES 467750 A3 ES467750 A3 ES 467750A3
Authority
ES
Spain
Prior art keywords
fermentation
tryptophan
translation
hydroxy
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0467750A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lasa Laboratorios SA
Original Assignee
Lasa Laboratorios SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lasa Laboratorios SA filed Critical Lasa Laboratorios SA
Priority to ES0467750A priority Critical patent/ES467750A3/en
Publication of ES467750A3 publication Critical patent/ES467750A3/en
Expired legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Process for obtaining l-5-hydroxy-tryptophan, essentially by microbiological fermentation of l-tryptophan or l-acetyltryptophan, by the action of non-pathogenic microorganisms selected from the families of the micrococcaceae, pseudomonadaceae, corynebacteriaceae, enterobacteriaceae and bacillaceae, characterized in that said fermentation is conducted at temperatures between 25º and 40ºC and ph of 6 to 8, feeding the crop an air flow between 1 and 5 liters/minute, in the presence of fe ions that increase the yield of fermentation and of ascorbic acid. Fermentative process, whose fe and ascorbic acid components are incorporated into the process at a time close to the end of the main growth of the microorganism, controlling the growth of the substrate by thin layer chromatography and following the fermentation, a separation of the bacterial cells of the culture broth by centrifugation or filtration and fixing of the l-5-hydroxytryptophan formed on a cation exchanger in the h form, from which the eluate is eluted and purified, once concentrated, with gel-dextran. (Machine-translation by Google Translate, not legally binding)
ES0467750A 1978-03-10 1978-03-10 Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding) Expired ES467750A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES0467750A ES467750A3 (en) 1978-03-10 1978-03-10 Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES0467750A ES467750A3 (en) 1978-03-10 1978-03-10 Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES467750A3 true ES467750A3 (en) 1978-10-16

Family

ID=8475625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0467750A Expired ES467750A3 (en) 1978-03-10 1978-03-10 Procedure for obtaining l-5-hydroxy-tryptophan. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES467750A3 (en)

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