ES465034A1 - Procedimiento para la preparacion de derivados de acidos n- (benzotiazol-2-il)-oxamidicos. - Google Patents
Procedimiento para la preparacion de derivados de acidos n- (benzotiazol-2-il)-oxamidicos.Info
- Publication number
- ES465034A1 ES465034A1 ES465034A ES465034A ES465034A1 ES 465034 A1 ES465034 A1 ES 465034A1 ES 465034 A ES465034 A ES 465034A ES 465034 A ES465034 A ES 465034A ES 465034 A1 ES465034 A1 ES 465034A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- preparation
- group
- r1r2r3
- signify
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RXUORKOATDNJFN-UHFFFAOYSA-N 2-(1,3-benzothiazol-2-ylamino)-2-oxoacetic acid Chemical class C1=CC=C2SC(NC(=O)C(=O)O)=NC2=C1 RXUORKOATDNJFN-UHFFFAOYSA-N 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000004190 benzothiazol-2-yl group Chemical group [H]C1=C([H])C([H])=C2N=C(*)SC2=C1[H] 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- -1 methylenedioxy group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762656468 DE2656468A1 (de) | 1976-12-14 | 1976-12-14 | N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES465034A1 true ES465034A1 (es) | 1978-09-01 |
Family
ID=5995427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES465034A Expired ES465034A1 (es) | 1976-12-14 | 1977-12-14 | Procedimiento para la preparacion de derivados de acidos n- (benzotiazol-2-il)-oxamidicos. |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5377058A (cg-RX-API-DMAC7.html) |
| AR (1) | AR216496A1 (cg-RX-API-DMAC7.html) |
| AT (1) | AT360523B (cg-RX-API-DMAC7.html) |
| AU (1) | AU510730B2 (cg-RX-API-DMAC7.html) |
| BE (1) | BE861794A (cg-RX-API-DMAC7.html) |
| CS (1) | CS203179B2 (cg-RX-API-DMAC7.html) |
| DD (1) | DD133329A5 (cg-RX-API-DMAC7.html) |
| DE (1) | DE2656468A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES465034A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI57594C (cg-RX-API-DMAC7.html) |
| FR (1) | FR2374317A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1538822A (cg-RX-API-DMAC7.html) |
| HU (1) | HU175340B (cg-RX-API-DMAC7.html) |
| NL (1) | NL7713580A (cg-RX-API-DMAC7.html) |
| SE (1) | SE7714074L (cg-RX-API-DMAC7.html) |
| SU (1) | SU680647A3 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA777236B (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2676775A (en) * | 1949-10-24 | 1954-04-27 | Gustav O Schulz | Electric flatiron cord holder |
| DE3017976A1 (de) * | 1980-05-10 | 1981-11-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4321372A (en) | 1980-06-16 | 1982-03-23 | Pfizer Inc. | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides |
| DE3027527A1 (de) | 1980-07-19 | 1982-02-18 | Basf Ag, 6700 Ludwigshafen | Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| GB2090826B (en) * | 1981-01-09 | 1985-06-12 | Usv Pharma Corp | New heterocyclic compounds useful as anti-allergie agents |
| DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
| FI91859C (fi) * | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| ATE385794T1 (de) | 2000-06-21 | 2008-03-15 | Hoffmann La Roche | Benzothiazolderivate zur behandlung von alzheimer und parkinson |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| ATE382619T1 (de) | 2004-05-24 | 2008-01-15 | Hoffmann La Roche | 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid |
| CN101056857B (zh) | 2004-11-05 | 2010-12-01 | 弗·哈夫曼-拉罗切有限公司 | 异烟酸衍生物的制备方法 |
| MX2007011483A (es) | 2005-03-23 | 2007-10-12 | Hoffmann La Roche | Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2. |
| AU2006298829B2 (en) | 2005-09-27 | 2011-03-03 | F. Hoffmann-La Roche Ag | Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4150140A (en) * | 1976-12-23 | 1979-04-17 | The Upjohn Company | Benzothiazolyl oxanic acids, esters and salts |
-
1976
- 1976-12-14 DE DE19762656468 patent/DE2656468A1/de not_active Withdrawn
-
1977
- 1977-12-03 HU HU77BO1695A patent/HU175340B/hu unknown
- 1977-12-05 ZA ZA00777236A patent/ZA777236B/xx unknown
- 1977-12-07 SU SU772550552A patent/SU680647A3/ru active
- 1977-12-07 CS CS778173A patent/CS203179B2/cs unknown
- 1977-12-07 AR AR270289A patent/AR216496A1/es active
- 1977-12-07 GB GB50911/77A patent/GB1538822A/en not_active Expired
- 1977-12-08 NL NL7713580A patent/NL7713580A/xx not_active Application Discontinuation
- 1977-12-08 AU AU31377/77A patent/AU510730B2/en not_active Expired
- 1977-12-08 DD DD7700202483A patent/DD133329A5/xx unknown
- 1977-12-12 SE SE7714074A patent/SE7714074L/xx not_active Application Discontinuation
- 1977-12-12 FI FI773738A patent/FI57594C/fi not_active IP Right Cessation
- 1977-12-13 FR FR7737467A patent/FR2374317A1/fr active Granted
- 1977-12-13 BE BE183407A patent/BE861794A/xx unknown
- 1977-12-13 AT AT890777A patent/AT360523B/de not_active IP Right Cessation
- 1977-12-14 JP JP15041777A patent/JPS5377058A/ja active Pending
- 1977-12-14 ES ES465034A patent/ES465034A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5377058A (en) | 1978-07-08 |
| DE2656468A1 (de) | 1978-06-15 |
| NL7713580A (nl) | 1978-06-16 |
| SU680647A3 (ru) | 1979-08-15 |
| AU510730B2 (en) | 1980-07-10 |
| CS203179B2 (en) | 1981-02-27 |
| FI57594C (fi) | 1980-09-10 |
| FR2374317A1 (fr) | 1978-07-13 |
| ZA777236B (en) | 1978-11-29 |
| BE861794A (fr) | 1978-06-13 |
| AR216496A1 (es) | 1979-12-28 |
| AT360523B (de) | 1981-01-12 |
| SE7714074L (sv) | 1978-06-15 |
| DD133329A5 (de) | 1978-12-27 |
| FI773738A7 (fi) | 1978-06-15 |
| FI57594B (fi) | 1980-05-30 |
| AU3137777A (en) | 1979-06-14 |
| HU175340B (hu) | 1980-07-28 |
| GB1538822A (en) | 1979-01-24 |
| FR2374317B1 (cg-RX-API-DMAC7.html) | 1980-11-07 |
| ATA890777A (de) | 1980-06-15 |
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