ES462470A1 - Preparation of 2*33dichloroo44 *22thenoyl*phenoxyacetic acid - Google Patents

Preparation of 2*33dichloroo44 *22thenoyl*phenoxyacetic acid

Info

Publication number
ES462470A1
ES462470A1 ES462470A ES462470A ES462470A1 ES 462470 A1 ES462470 A1 ES 462470A1 ES 462470 A ES462470 A ES 462470A ES 462470 A ES462470 A ES 462470A ES 462470 A1 ES462470 A1 ES 462470A1
Authority
ES
Spain
Prior art keywords
22thenoyl
preparation
phenoxyacetic acid
compound
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462470A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Albert Rolland SA
Original Assignee
Laboratoires Albert Rolland SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Albert Rolland SA filed Critical Laboratoires Albert Rolland SA
Publication of ES462470A1 publication Critical patent/ES462470A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

This compound, also called tienilic acid, is a diuretic and uricosuric agent used in therapeutics. According to the invention, it is obtained in the very pure state in a single operation by decarboxylating, by heating, a compound of formula I in which R is a hydrogen atom or an alkyl group. When R is an alkyl group, the phenoxyacetic ester obtained is hydrolysed.
ES462470A 1976-09-21 1977-09-20 Preparation of 2*33dichloroo44 *22thenoyl*phenoxyacetic acid Expired ES462470A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7628272A FR2364914A1 (en) 1976-09-21 1976-09-21 PROCESS FOR THE PREPARATION OF DICHLORO-2,3 (THENOYL-2) -4 PHENOXY-ACETIC ACID

Publications (1)

Publication Number Publication Date
ES462470A1 true ES462470A1 (en) 1978-07-16

Family

ID=9177879

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462470A Expired ES462470A1 (en) 1976-09-21 1977-09-20 Preparation of 2*33dichloroo44 *22thenoyl*phenoxyacetic acid

Country Status (11)

Country Link
JP (1) JPS5340756A (en)
CA (1) CA1089475A (en)
CH (1) CH623048A5 (en)
ES (1) ES462470A1 (en)
FR (1) FR2364914A1 (en)
GR (1) GR63627B (en)
HU (1) HU173514B (en)
IL (1) IL52879A (en)
IT (1) IT1086081B (en)
PL (1) PL200936A1 (en)
PT (1) PT67033B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60005C (en) * 1979-11-27 1981-11-10 Farmos Oy ETT NYTT FOERFARANDE FOER FRAMSTAELLNING AV (2,3-DICHLORO-4- (2-THIENYLCARBONYL) PHENOXY) -AETHYXY MED THERAPEUTIC ACTIVITIES SAMT (2,3-DICHLORO-4- (2-THIENYL CARBONYL) FENOXYAN) FOERFARANDET
JPH0632887B2 (en) * 1986-08-29 1994-05-02 株式会社日立製作所 Chamfering method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793212C3 (en) * 1967-08-31 1974-02-21 Egyt Gyogyszervegyeszeti Gyar, Budapest Process for the preparation of 2,3-dichloro-4-butyryl-phenoxyacetic acid

Also Published As

Publication number Publication date
PT67033A (en) 1977-10-01
JPS5340756A (en) 1978-04-13
CA1089475A (en) 1980-11-11
IL52879A (en) 1981-09-13
GR63627B (en) 1979-11-27
IT1086081B (en) 1985-05-28
PT67033B (en) 1979-02-15
FR2364914A1 (en) 1978-04-14
FR2364914B1 (en) 1980-07-25
PL200936A1 (en) 1978-05-22
IL52879A0 (en) 1977-11-30
HU173514B (en) 1979-05-28
CH623048A5 (en) 1981-05-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980302