ES462229A1 - Un procedimiento para preparar una indol dihiindolcarboxami-da dimerica. - Google Patents

Un procedimiento para preparar una indol dihiindolcarboxami-da dimerica.

Info

Publication number
ES462229A1
ES462229A1 ES462229A ES462229A ES462229A1 ES 462229 A1 ES462229 A1 ES 462229A1 ES 462229 A ES462229 A ES 462229A ES 462229 A ES462229 A ES 462229A ES 462229 A1 ES462229 A1 ES 462229A1
Authority
ES
Spain
Prior art keywords
alkaloids
vinblastine
carboxamido derivatives
amine
dimeric indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462229A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES462229A1 publication Critical patent/ES462229A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES462229A 1976-09-08 1977-09-08 Un procedimiento para preparar una indol dihiindolcarboxami-da dimerica. Expired ES462229A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (1)

Publication Number Publication Date
ES462229A1 true ES462229A1 (es) 1978-07-16

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462229A Expired ES462229A1 (es) 1976-09-08 1977-09-08 Un procedimiento para preparar una indol dihiindolcarboxami-da dimerica.

Country Status (27)

Country Link
JP (1) JPS5340799A (fi)
AR (3) AR226411A1 (fi)
AT (1) AT360513B (fi)
AU (1) AU511055B2 (fi)
BE (1) BE858451A (fi)
CA (1) CA1082179A (fi)
CH (1) CH631990A5 (fi)
DD (1) DD133055A5 (fi)
DE (1) DE2739443A1 (fi)
DK (1) DK146822C (fi)
ES (1) ES462229A1 (fi)
FR (1) FR2364220A1 (fi)
GB (1) GB1586709A (fi)
GR (1) GR69783B (fi)
HU (1) HU180722B (fi)
IE (1) IE45558B1 (fi)
IL (1) IL52731A0 (fi)
MX (1) MX4740E (fi)
NL (1) NL7709806A (fi)
NZ (1) NZ184932A (fi)
PH (1) PH14771A (fi)
PL (1) PL104309B1 (fi)
PT (1) PT66984B (fi)
RO (3) RO77922A (fi)
SE (1) SE434953B (fi)
YU (1) YU209777A (fi)
ZA (1) ZA774988B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Also Published As

Publication number Publication date
NL7709806A (nl) 1978-03-10
DK398577A (da) 1978-03-09
CH631990A5 (en) 1982-09-15
PH14771A (en) 1981-12-09
PT66984B (en) 1979-02-13
PT66984A (en) 1977-10-01
GB1586709A (en) 1981-03-25
GR69783B (fi) 1982-07-07
ZA774988B (en) 1979-03-28
IL52731A0 (en) 1977-10-31
DE2739443C2 (fi) 1991-08-14
RO77921A (ro) 1981-12-25
ATA644277A (de) 1980-06-15
BE858451A (fr) 1978-03-07
HU180722B (en) 1983-04-29
AR230642A1 (es) 1984-05-31
RO77922A (ro) 1981-12-25
SE7710059L (sv) 1978-03-09
DK146822B (da) 1984-01-16
RO72474A (ro) 1982-05-10
DE2739443A1 (de) 1978-03-09
FR2364220B1 (fi) 1980-04-25
DK146822C (da) 1984-06-25
DD133055A5 (de) 1978-11-29
FR2364220A1 (fr) 1978-04-07
AU2803977A (en) 1979-02-22
IE771700L (en) 1978-03-08
CA1082179A (en) 1980-07-22
AR226411A1 (es) 1982-07-15
AT360513B (de) 1981-01-12
PL200607A1 (pl) 1978-05-22
NZ184932A (en) 1979-11-01
JPS5340799A (en) 1978-04-13
AR231643A1 (es) 1985-01-31
AU511055B2 (en) 1980-07-24
PL104309B1 (pl) 1979-08-31
IE45558B1 (en) 1982-09-22
YU209777A (en) 1982-08-31
MX4740E (es) 1982-08-25
JPS624398B2 (fi) 1987-01-30
SE434953B (sv) 1984-08-27

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