ES457244A1 - Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. - Google Patents
Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina.Info
- Publication number
- ES457244A1 ES457244A1 ES457244A ES457244A ES457244A1 ES 457244 A1 ES457244 A1 ES 457244A1 ES 457244 A ES457244 A ES 457244A ES 457244 A ES457244 A ES 457244A ES 457244 A1 ES457244 A1 ES 457244A1
- Authority
- ES
- Spain
- Prior art keywords
- ethanolamine
- chlorophenoxy
- prepn
- ethyl nicotinate
- hypolipaemic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 title abstract 8
- XBLVHTDFJBKJLG-UHFFFAOYSA-N Ethyl nicotinate Chemical compound CCOC(=O)C1=CC=CN=C1 XBLVHTDFJBKJLG-UHFFFAOYSA-N 0.000 title abstract 6
- OODRWLGKUBMFLZ-UHFFFAOYSA-N 2-(4-chlorophenoxy)-2-methylpropanoyl chloride Chemical compound ClC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 OODRWLGKUBMFLZ-UHFFFAOYSA-N 0.000 title abstract 3
- 229940064982 ethylnicotinate Drugs 0.000 title abstract 3
- 230000000055 hyoplipidemic effect Effects 0.000 title 1
- 230000000871 hypocholesterolemic effect Effects 0.000 title 1
- 229940031098 ethanolamine Drugs 0.000 abstract 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 abstract 2
- KMQANHOODDGGJW-UHFFFAOYSA-N Cl.C(C(C)C)(=O)C(O)CN Chemical compound Cl.C(C(C)C)(=O)C(O)CN KMQANHOODDGGJW-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7609253A FR2346010A2 (fr) | 1976-03-29 | 1976-03-29 | Procede de preparation du chlorhydrate de n-nicotinoyl o-p-chloro phenoxy isobutanoyl ethanol amine, utile dans le traitement des dislipidemies et la prevention de l'atherosclerose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES457244A1 true ES457244A1 (es) | 1978-02-01 |
Family
ID=9171169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES457244A Expired ES457244A1 (es) | 1976-03-29 | 1977-03-26 | Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. |
Country Status (4)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619938A (en) * | 1984-03-21 | 1986-10-28 | Terumo Kabushiki Kaisha | Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors |
-
1976
- 1976-03-29 FR FR7609253A patent/FR2346010A2/fr active Granted
-
1977
- 1977-03-26 ES ES457244A patent/ES457244A1/es not_active Expired
- 1977-03-28 CA CA274,862A patent/CA1095051A/fr not_active Expired
- 1977-03-29 ZA ZA00771892A patent/ZA771892B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2346010B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-05-18 |
| CA1095051A (fr) | 1981-02-03 |
| ZA771892B (en) | 1978-03-29 |
| FR2346010A2 (fr) | 1977-10-28 |
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