ES457244A1 - Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. - Google Patents
Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina.Info
- Publication number
- ES457244A1 ES457244A1 ES457244A ES457244A ES457244A1 ES 457244 A1 ES457244 A1 ES 457244A1 ES 457244 A ES457244 A ES 457244A ES 457244 A ES457244 A ES 457244A ES 457244 A1 ES457244 A1 ES 457244A1
- Authority
- ES
- Spain
- Prior art keywords
- ethanolamine
- chlorophenoxy
- prepn
- ethyl nicotinate
- hypolipaemic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
Un procedimiento de preparación del clorhidrato de N-nicotinoil-O-p-cloro-fenoxi-isobutanoil-etanol-amina de fórmula *** ver imagen 01 caracterizado porque se aminoliza nicotinato de etilo por etanol-amina y porque se trata in situ la N-(hidroxi-2-etil)-nicotinamida por cloruro de p-cloro-fenoxi-isobutiroilo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7609253A FR2346010A2 (fr) | 1976-03-29 | 1976-03-29 | Procede de preparation du chlorhydrate de n-nicotinoyl o-p-chloro phenoxy isobutanoyl ethanol amine, utile dans le traitement des dislipidemies et la prevention de l'atherosclerose |
Publications (1)
Publication Number | Publication Date |
---|---|
ES457244A1 true ES457244A1 (es) | 1978-02-01 |
Family
ID=9171169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES457244A Expired ES457244A1 (es) | 1976-03-29 | 1977-03-26 | Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. |
Country Status (4)
Country | Link |
---|---|
CA (1) | CA1095051A (es) |
ES (1) | ES457244A1 (es) |
FR (1) | FR2346010A2 (es) |
ZA (1) | ZA771892B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4619938A (en) * | 1984-03-21 | 1986-10-28 | Terumo Kabushiki Kaisha | Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors |
-
1976
- 1976-03-29 FR FR7609253A patent/FR2346010A2/fr active Granted
-
1977
- 1977-03-26 ES ES457244A patent/ES457244A1/es not_active Expired
- 1977-03-28 CA CA274,862A patent/CA1095051A/fr not_active Expired
- 1977-03-29 ZA ZA00771892A patent/ZA771892B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FR2346010A2 (fr) | 1977-10-28 |
CA1095051A (fr) | 1981-02-03 |
ZA771892B (en) | 1978-03-29 |
FR2346010B2 (es) | 1979-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES457244A1 (es) | Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. | |
ES440247A1 (es) | Un procedimiento para recuperar el 1, 2-dicloroetano de una mezcla de 1, 2-dicloroetano e hidrocarburos clorados mas pe-sados que el 1, 2-dicloroetano. | |
NL7706803A (en) | Hypolipaemic and hypocholesterolaemic ethanolamine derivs. prepn. - by treating ethyl nicotinate with ethanolamine and then with p-chlorophenoxy-isobutyroyl chloride | |
ES8505916A1 (es) | Procedimiento para la obtencion de acido formico por destilacion. | |
IL49013A (en) | Process for the substitution of the chlorine atoms of cyanuric chloride by amines | |
GB1505633A (en) | 3,5-bis(acylamino)benzamides | |
IE44449L (en) | Morphanthridines | |
ES333713A1 (es) | Procedimiento de preparacion de benzamidas sustituidas. | |
IL64844A0 (en) | N-substituted polyglycidyl urazole compounds,their production and pharmaceutical preparations containing them | |
GB816588A (en) | Improvements in the purification of acetylene | |
ES466909A1 (es) | Procedimiento quimico para la sintesis industrial del cloro-formiato y del tiocloroformiato de vinilo y de isopropenilo. | |
ES268422A1 (es) | Procedimiento para la preparacion de nuevos derivados de glucosamina | |
GB901891A (en) | Fluorinated amides | |
GB979657A (en) | Process for the production of unsymmetrically substituted 1,3,5-triazines | |
NL7512200A (nl) | Werkwijze voor het verwijderen van fluorwaterstof uit gasvormige mengsels door absorptie op aardal- kalimetaalfluoride. | |
GB894720A (en) | Process for the purification of dark-coloured crude fatty acid amides | |
ES283770A1 (es) | Procedimiento para preparar nuevos derivados de sulfanilamida | |
ES483076A1 (es) | Procedimiento para la purificacion de triptofano y derivadosde triptofano | |
GB1492380A (en) | Substituted trithiolans and their use as flavouring agent | |
GB1398202A (en) | Process for the preparation of alpha-oximinonitriles | |
GB955352A (en) | Method of preparing polynitro compounds | |
GB1443406A (en) | Purification of coumarin and alkylated derivatives thereof | |
ES290275A2 (es) | Procedimiento para preparar nuevos compuestos de la 6-metil y la 1,6-dimetil-er-golina ii | |
ES447297A1 (es) | Procedimiento para la preparacion den-acetoacetil-2,5-dime- toxi-4-cloroanilina. | |
GB1519911A (en) | Reaction products of sulphur dioxide with schiff's bases and their use as metal treatment agents |