ES456632A1 - Procedimiento para la preparacion de derivados de aziridina. - Google Patents
Procedimiento para la preparacion de derivados de aziridina.Info
- Publication number
- ES456632A1 ES456632A1 ES456632A ES456632A ES456632A1 ES 456632 A1 ES456632 A1 ES 456632A1 ES 456632 A ES456632 A ES 456632A ES 456632 A ES456632 A ES 456632A ES 456632 A1 ES456632 A1 ES 456632A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- group
- nitrile
- phenyl
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical class C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 title 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 150000002825 nitriles Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001541 aziridines Chemical class 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- -1 dialkohylamino Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762610156 DE2610156A1 (de) | 1976-03-11 | 1976-03-11 | 1-eckige klammer auf 2-cyanaziridinyl-(1)eckige klammer zu-1-eckige klammer auf 2-carbamoyl-aziridinyl- (1)eckige klammer zu-cyclohexan |
| DE19762632517 DE2632517A1 (de) | 1976-07-20 | 1976-07-20 | 2- eckige klammer auf 2-cyanaziridinyl- (1) eckige klammer zu -2- eckige klammer auf 2-carbamoyl-aziridinyl-(1) eckige klammer zu -propan und verfahren zu dessen herstellung |
| DE19762656240 DE2656240C2 (de) | 1976-12-11 | 1976-12-11 | Neue Aziridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456632A1 true ES456632A1 (es) | 1978-01-16 |
Family
ID=27186778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456632A Expired ES456632A1 (es) | 1976-03-11 | 1977-03-08 | Procedimiento para la preparacion de derivados de aziridina. |
Country Status (28)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT386195B (de) * | 1978-08-03 | 1988-07-11 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von neuen n-substituierten aziridin-2-carbonsaeurederivaten und ihren salzen |
| US4925835A (en) * | 1986-05-01 | 1990-05-15 | Sloan-Kettering Institute For Cancer Research | Aziridinyl putrescine containing compositions and their uses in treating prostate cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3828024A (en) * | 1970-12-21 | 1974-08-06 | Hercules Inc | Poly(aziridine)s |
-
1977
- 1977-03-03 CA CA273,107A patent/CA1086321A/en not_active Expired
- 1977-03-06 EG EG137/77A patent/EG13513A/xx active
- 1977-03-07 IL IL51602A patent/IL51602A/xx unknown
- 1977-03-07 DK DK098577AA patent/DK154832B/da not_active Application Discontinuation
- 1977-03-07 SE SE7702521A patent/SE436128B/xx not_active IP Right Cessation
- 1977-03-07 GB GB9499/77A patent/GB1518494A/en not_active Expired
- 1977-03-07 FI FI770718A patent/FI67212C/fi not_active IP Right Cessation
- 1977-03-07 PT PT66275A patent/PT66275B/pt unknown
- 1977-03-07 IT IT21008/77A patent/IT1076885B/it active
- 1977-03-08 AT AT154277A patent/AT351043B/de not_active IP Right Cessation
- 1977-03-08 ES ES456632A patent/ES456632A1/es not_active Expired
- 1977-03-08 DD DD7700197731A patent/DD128615A5/xx unknown
- 1977-03-08 NZ NZ183528A patent/NZ183528A/xx unknown
- 1977-03-09 US US05/776,068 patent/US4370323A/en not_active Expired - Lifetime
- 1977-03-09 IE IE518/77A patent/IE44640B1/en unknown
- 1977-03-09 YU YU00630/77A patent/YU63077A/xx unknown
- 1977-03-09 CH CH296577A patent/CH629770A5/de not_active IP Right Cessation
- 1977-03-09 NL NLAANVRAGE7702527,A patent/NL177916C/xx not_active IP Right Cessation
- 1977-03-09 LU LU76918A patent/LU76918A1/xx unknown
- 1977-03-09 JP JP2586777A patent/JPS52111563A/ja active Granted
- 1977-03-09 GR GR52957A patent/GR73009B/el unknown
- 1977-03-09 HU HU77BO1654A patent/HU176646B/hu unknown
- 1977-03-09 PL PL1977196543A patent/PL106627B1/pl unknown
- 1977-03-10 FR FR7707061A patent/FR2343739A1/fr active Granted
- 1977-03-10 NO NO770847A patent/NO147185C/no unknown
- 1977-03-11 AR AR266818A patent/AR214733A1/es active
- 1977-03-11 SU SU772459152A patent/SU673167A3/ru active
- 1977-03-11 OA OA56096A patent/OA05594A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981103 |