ES454939A1 - Un procedimiento de preparacion de derivados de 2-aminoinda-no. - Google Patents
Un procedimiento de preparacion de derivados de 2-aminoinda-no.Info
- Publication number
- ES454939A1 ES454939A1 ES454939A ES454939A ES454939A1 ES 454939 A1 ES454939 A1 ES 454939A1 ES 454939 A ES454939 A ES 454939A ES 454939 A ES454939 A ES 454939A ES 454939 A1 ES454939 A1 ES 454939A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- aminoindane
- phenyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LMHHFZAXSANGGM-UHFFFAOYSA-N 2-aminoindane Chemical class C1=CC=C2CC(N)CC2=C1 LMHHFZAXSANGGM-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 150000001412 amines Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- MHVHCDLCLNXADJ-UHFFFAOYSA-N n-phenyl-2,3-dihydro-1h-inden-2-amine Chemical compound C1C2=CC=CC=C2CC1NC1=CC=CC=C1 MHVHCDLCLNXADJ-UHFFFAOYSA-N 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 229910018954 NaNH2 Inorganic materials 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- ZBRGOLQQTDZDDU-UHFFFAOYSA-N Cl.NC1CC2=CC=CC=C2C1C1=CC=CC=C1 Chemical compound Cl.NC1CC2=CC=CC=C2C1C1=CC=CC=C1 ZBRGOLQQTDZDDU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- -1 benzene or toluene Chemical compound 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU74197A LU74197A1 (en:Method) | 1976-01-16 | 1976-01-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES454939A1 true ES454939A1 (es) | 1977-12-01 |
Family
ID=19728141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES454939A Expired ES454939A1 (es) | 1976-01-16 | 1977-01-11 | Un procedimiento de preparacion de derivados de 2-aminoinda-no. |
Country Status (21)
| Country | Link |
|---|---|
| AR (1) | AR211042A1 (en:Method) |
| AT (1) | AT347444B (en:Method) |
| AU (1) | AU503658B2 (en:Method) |
| CA (1) | CA1068289A (en:Method) |
| CH (1) | CH617663A5 (en:Method) |
| CS (1) | CS193538B2 (en:Method) |
| DD (1) | DD123598A5 (en:Method) |
| DK (1) | DK4677A (en:Method) |
| ES (1) | ES454939A1 (en:Method) |
| FI (1) | FI770039A7 (en:Method) |
| HU (1) | HU174694B (en:Method) |
| IL (1) | IL51125A (en:Method) |
| LU (1) | LU74197A1 (en:Method) |
| MX (1) | MX4651E (en:Method) |
| NO (1) | NO143217C (en:Method) |
| NZ (1) | NZ182904A (en:Method) |
| PL (1) | PL104367B1 (en:Method) |
| PT (1) | PT66020B (en:Method) |
| SE (1) | SE7700321L (en:Method) |
| SU (1) | SU640658A3 (en:Method) |
| ZA (1) | ZA767468B (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7718674B2 (en) | 2004-09-27 | 2010-05-18 | Bridge Pharma, Inc. | Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine |
| CA2655809C (en) | 2006-07-21 | 2013-10-01 | Bridge Pharma, Inc. | Dermal anesthetic compounds |
-
1976
- 1976-01-16 LU LU74197A patent/LU74197A1/xx unknown
- 1976-03-01 DD DD191667A patent/DD123598A5/xx unknown
- 1976-03-04 HU HU76CI1646A patent/HU174694B/hu unknown
- 1976-03-11 CS CS761606A patent/CS193538B2/cs unknown
- 1976-03-12 PL PL1976187911A patent/PL104367B1/pl unknown
- 1976-03-16 SU SU762333209A patent/SU640658A3/ru active
- 1976-12-15 CA CA267,951A patent/CA1068289A/en not_active Expired
- 1976-12-15 ZA ZA767468A patent/ZA767468B/xx unknown
- 1976-12-16 NZ NZ182904A patent/NZ182904A/xx unknown
- 1976-12-17 IL IL51125A patent/IL51125A/xx unknown
- 1976-12-17 AU AU20677/76A patent/AU503658B2/en not_active Expired
- 1976-12-27 AT AT966976A patent/AT347444B/de not_active IP Right Cessation
- 1976-12-28 PT PT66020A patent/PT66020B/pt unknown
-
1977
- 1977-01-05 AR AR266112A patent/AR211042A1/es active
- 1977-01-05 MX MX775301U patent/MX4651E/es unknown
- 1977-01-06 DK DK4677A patent/DK4677A/da unknown
- 1977-01-06 FI FI770039A patent/FI770039A7/fi not_active Application Discontinuation
- 1977-01-11 ES ES454939A patent/ES454939A1/es not_active Expired
- 1977-01-13 SE SE7700321A patent/SE7700321L/xx unknown
- 1977-01-14 NO NO770126A patent/NO143217C/no unknown
- 1977-01-14 CH CH49977A patent/CH617663A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT66020A (en) | 1977-01-01 |
| AT347444B (de) | 1978-12-27 |
| AU503658B2 (en) | 1979-09-13 |
| IL51125A (en) | 1980-06-30 |
| LU74197A1 (en:Method) | 1977-07-22 |
| PL104367B1 (pl) | 1979-08-31 |
| NO143217C (no) | 1981-01-07 |
| DD123598A5 (en:Method) | 1977-01-05 |
| HU174694B (hu) | 1980-03-28 |
| NO770126L (no) | 1977-07-19 |
| ATA966976A (de) | 1978-05-15 |
| MX4651E (es) | 1982-07-16 |
| IL51125A0 (en) | 1977-02-28 |
| DK4677A (da) | 1977-07-17 |
| CH617663A5 (en) | 1980-06-13 |
| NO143217B (no) | 1980-09-22 |
| ZA767468B (en) | 1977-11-30 |
| SU640658A3 (ru) | 1978-12-30 |
| AR211042A1 (es) | 1977-10-14 |
| NZ182904A (en) | 1979-01-11 |
| AU2067776A (en) | 1978-06-22 |
| PT66020B (en) | 1978-06-19 |
| CS193538B2 (en) | 1979-10-31 |
| CA1068289A (en) | 1979-12-18 |
| FI770039A7 (en:Method) | 1977-07-17 |
| SE7700321L (sv) | 1977-07-17 |
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