ES454888A1 - Un procedimiento para la preparacion de nuevos cromados. - Google Patents

Un procedimiento para la preparacion de nuevos cromados.

Info

Publication number
ES454888A1
ES454888A1 ES454888A ES454888A ES454888A1 ES 454888 A1 ES454888 A1 ES 454888A1 ES 454888 A ES454888 A ES 454888A ES 454888 A ES454888 A ES 454888A ES 454888 A1 ES454888 A1 ES 454888A1
Authority
ES
Spain
Prior art keywords
preparation
composition containing
containing same
antihypertensives
piperidino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454888A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB3024/76A external-priority patent/GB1548221A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES454888A1 publication Critical patent/ES454888A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Un procedimiento para la preparación de nuevos cromanos de fórmula (II): **(Fórmula)** y sales de los mismos, donde R9 es un grupo metilo o etilo; R10 es un átomo de hidrógeno o un grupo metilo; R11 es un átomo de hidrógeno o un grupo metilo; R12 es un átomo de hidrógeno o halógeno o un grupo alquilo C1-6, alquenilo C2-6, alcoxilo C1-6, alquenoxilo C2-6. aquiltio C1-6, nitro, trifluorometilo, acilamino C2-7 o nitrilo; R13 es un grupo R14 u OR14, donde R14 es un grupo hidrocarburo de hasta 18 átomos de carbono, opcionalmente sustituido con halógeno y X es un enlace que uno los dos átomos de carbono o es un grupo -CH2-, -CH2CH2-, -CH2-CH2-CH2- o -CH=CH- o un átomo de oxígeno.
ES454888A 1976-01-27 1977-01-07 Un procedimiento para la preparacion de nuevos cromados. Expired ES454888A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3024/76A GB1548221A (en) 1976-01-27 1976-01-27 Trans-4-heterocycyl-3,4-dihydro-2h-benzo pyran-3-ol esters
GB1423976 1976-04-08

Publications (1)

Publication Number Publication Date
ES454888A1 true ES454888A1 (es) 1978-05-01

Family

ID=26237940

Family Applications (1)

Application Number Title Priority Date Filing Date
ES454888A Expired ES454888A1 (es) 1976-01-27 1977-01-07 Un procedimiento para la preparacion de nuevos cromados.

Country Status (9)

Country Link
JP (1) JPS5291866A (es)
AU (1) AU505768B2 (es)
DE (1) DE2702092A1 (es)
DK (1) DK31977A (es)
ES (1) ES454888A1 (es)
FR (1) FR2339606A1 (es)
IE (1) IE44588B1 (es)
NL (1) NL7700819A (es)
SE (1) SE7700824L (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795275B (en) * 1978-10-04 1980-09-24 Beecham Group Ltd Chromanol derivatives a process for their preparation and their use in pharmaceutical compositions
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
GB8313679D0 (en) * 1983-05-18 1983-06-22 Beecham Group Plc Active compounds
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
US5352814A (en) * 1991-08-30 1994-10-04 Nissan Chemical Industries, Ltd. Asymmetric epoxidation reaction
AU7319800A (en) 1999-09-24 2001-04-24 Nissan Chemical Industries Ltd. 4-oxybenzopyran derivative
US6677371B1 (en) 1999-10-05 2004-01-13 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
DE60206505T2 (de) 2001-06-25 2006-07-06 Nissan Chemical Industries, Ltd. Substituierte benzopyranderivate gegen arrhytmie

Also Published As

Publication number Publication date
SE7700824L (sv) 1977-07-28
FR2339606B1 (es) 1981-01-16
DK31977A (da) 1977-07-28
AU505768B2 (en) 1979-11-29
DE2702092A1 (de) 1977-07-28
NL7700819A (nl) 1977-07-29
AU2162577A (en) 1978-08-03
IE44588L (en) 1977-07-27
JPS5291866A (en) 1977-08-02
IE44588B1 (en) 1982-01-27
FR2339606A1 (fr) 1977-08-26

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