ES451829A1 - Novel 11benzoyll22*2*6** dichlorphenylamino**22 imidazoline * salts and preparation thereof - Google Patents

Novel 11benzoyll22*2*6** dichlorphenylamino**22 imidazoline * salts and preparation thereof

Info

Publication number
ES451829A1
ES451829A1 ES451829A ES451829A ES451829A1 ES 451829 A1 ES451829 A1 ES 451829A1 ES 451829 A ES451829 A ES 451829A ES 451829 A ES451829 A ES 451829A ES 451829 A1 ES451829 A1 ES 451829A1
Authority
ES
Spain
Prior art keywords
formula
imidazoline
salts
preparation
dichlorphenylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES451829A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
Chemie Linz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz AG filed Critical Chemie Linz AG
Publication of ES451829A1 publication Critical patent/ES451829A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)

Abstract

Process for the preparation of 1-benzoyl-2- (2 ', 6'-dichlorophenylamino) -2-imidazoline of the formula ** (see formula) ** Or its salts, characterized in that 2,6-dichlorophenylisocyanide dihalides of the general formula ** (see formula) ** Where x means halogen, preferably chlorine, are reacted with benzoylethylenediamine in an inert solvent with respect to the reactants at temperatures from 0ºC up to the boiling point of the solvent used under the addition of acid acceptors, after which the obtained compound of formula (ia) or (ib) is isolated as a base or salt with inorganic or organic acids. (Machine-translation by Google Translate, not legally binding)
ES451829A 1975-09-25 1976-09-24 Novel 11benzoyll22*2*6** dichlorphenylamino**22 imidazoline * salts and preparation thereof Expired ES451829A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT735575A AT339897B (en) 1975-09-25 1975-09-25 PROCESS FOR PREPARING THE NEW 1-BENZOYL-2- (2 ', 6'-DICHLOROPHENYLAMINO) -2-IMIDAZOLINE AND THE SALT THEREOF

Publications (1)

Publication Number Publication Date
ES451829A1 true ES451829A1 (en) 1977-11-01

Family

ID=3595222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES451829A Expired ES451829A1 (en) 1975-09-25 1976-09-24 Novel 11benzoyll22*2*6** dichlorphenylamino**22 imidazoline * salts and preparation thereof

Country Status (18)

Country Link
JP (1) JPS5239675A (en)
AT (1) AT339897B (en)
BG (1) BG35040A3 (en)
CA (1) CA1062267A (en)
CH (1) CH601253A5 (en)
CS (1) CS196324B2 (en)
DD (1) DD126907A1 (en)
DK (1) DK144565C (en)
ES (1) ES451829A1 (en)
FI (1) FI63752C (en)
NL (1) NL7608971A (en)
NO (1) NO145274C (en)
PL (1) PL100503B1 (en)
PT (1) PT65438B (en)
RO (1) RO69914A (en)
SE (1) SE439010B (en)
SU (1) SU604488A3 (en)
YU (1) YU39360B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MTP837B (en) * 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE2811847A1 (en) * 1978-03-17 1979-09-20 Lentia Gmbh NEW ARYLAMINOIMIDAZOLINE DERIVATIVES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS
DE3200258A1 (en) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO IMIDAZOLIDINE, THE ACID ADDITION SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME

Also Published As

Publication number Publication date
ATA735575A (en) 1977-03-15
DK354376A (en) 1977-03-26
YU39360B (en) 1984-10-31
PT65438A (en) 1976-09-01
NO145274B (en) 1981-11-09
PT65438B (en) 1978-02-09
DD126907A1 (en) 1977-08-17
JPS5333592B2 (en) 1978-09-14
SE439010B (en) 1985-05-28
YU184876A (en) 1982-06-30
NO145274C (en) 1982-02-17
DK144565B (en) 1982-03-29
DK144565C (en) 1982-09-13
CS196324B2 (en) 1980-03-31
JPS5239675A (en) 1977-03-28
CH601253A5 (en) 1978-06-30
SU604488A3 (en) 1978-04-25
RO69914A (en) 1981-06-30
BG35040A3 (en) 1984-01-16
PL100503B1 (en) 1978-10-31
NO762439L (en) 1977-03-28
FI762025A (en) 1977-03-26
SE7609391L (en) 1977-03-26
FI63752B (en) 1983-04-29
FI63752C (en) 1983-08-10
AT339897B (en) 1977-11-10
CA1062267A (en) 1979-09-11
NL7608971A (en) 1977-03-29

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