SE7609391L - METHOD OF PREPARING 1-BENZOYL-2- (2 ', 6'-DICHLOROPHENYLAMINO) -2-IMIDAZOLINE AND SALTS thereof - Google Patents
METHOD OF PREPARING 1-BENZOYL-2- (2 ', 6'-DICHLOROPHENYLAMINO) -2-IMIDAZOLINE AND SALTS thereofInfo
- Publication number
- SE7609391L SE7609391L SE7609391A SE7609391A SE7609391L SE 7609391 L SE7609391 L SE 7609391L SE 7609391 A SE7609391 A SE 7609391A SE 7609391 A SE7609391 A SE 7609391A SE 7609391 L SE7609391 L SE 7609391L
- Authority
- SE
- Sweden
- Prior art keywords
- dichlorophenylamino
- imidazoline
- benzoyl
- salts
- degree
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
PROCESS FOR THE PREPARATION OF 1-BENZOYL-2-(2',6'-DICHLOROPHENYLAMINO)-2-IMIDAZOLINE AND SALTS THEREOF A process for the preparation of 1-berzoyl-2-(2',6'-dichlorophenylamino)-2-imidazoline or a salt thereof, which comprises reacting a 2,6-dichlorophenyl-isocyanide dihalide with benzoylethylenediamine in a solvent inert to the reactants at a temperature from 0.degree.C. up to the boiling point of the solvent used, preferably from +10.degree.C. to +50.degree.C., in the presence of an acidbinding agent, and isolating the desired product as the free base or a salt with an inorganic or organic acid.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT735575A AT339897B (en) | 1975-09-25 | 1975-09-25 | PROCESS FOR PREPARING THE NEW 1-BENZOYL-2- (2 ', 6'-DICHLOROPHENYLAMINO) -2-IMIDAZOLINE AND THE SALT THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7609391L true SE7609391L (en) | 1977-03-26 |
| SE439010B SE439010B (en) | 1985-05-28 |
Family
ID=3595222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7609391A SE439010B (en) | 1975-09-25 | 1976-08-25 | SET TO PREPARE 1-BENZOYL-2- (2 ', 6'-DICHLORPHENYLAMINO) -2-IMIDAZOLINE AND SALTS THEREOF |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5239675A (en) |
| AT (1) | AT339897B (en) |
| BG (1) | BG35040A3 (en) |
| CA (1) | CA1062267A (en) |
| CH (1) | CH601253A5 (en) |
| CS (1) | CS196324B2 (en) |
| DD (1) | DD126907A1 (en) |
| DK (1) | DK144565C (en) |
| ES (1) | ES451829A1 (en) |
| FI (1) | FI63752C (en) |
| NL (1) | NL7608971A (en) |
| NO (1) | NO145274C (en) |
| PL (1) | PL100503B1 (en) |
| PT (1) | PT65438B (en) |
| RO (1) | RO69914A (en) |
| SE (1) | SE439010B (en) |
| SU (1) | SU604488A3 (en) |
| YU (1) | YU39360B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MTP837B (en) * | 1977-11-07 | 1979-10-22 | Hoffman La Roche And Co Aktien | Derivatives 2 finino-imidazolidire |
| DE2811847A1 (en) | 1978-03-17 | 1979-09-20 | Lentia Gmbh | NEW ARYLAMINOIMIDAZOLINE DERIVATIVES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS |
| DE3200258A1 (en) * | 1982-01-07 | 1983-07-21 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO IMIDAZOLIDINE, THE ACID ADDITION SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME |
-
1975
- 1975-09-25 AT AT735575A patent/AT339897B/en not_active IP Right Cessation
-
1976
- 1976-07-05 CH CH859676A patent/CH601253A5/en not_active IP Right Cessation
- 1976-07-12 FI FI762025A patent/FI63752C/en not_active IP Right Cessation
- 1976-07-12 NO NO762439A patent/NO145274C/en unknown
- 1976-07-21 BG BG7633815A patent/BG35040A3/en unknown
- 1976-07-27 YU YU1848/76A patent/YU39360B/en unknown
- 1976-07-28 RO RO7687139A patent/RO69914A/en unknown
- 1976-08-04 PT PT65438A patent/PT65438B/en unknown
- 1976-08-06 DK DK354376A patent/DK144565C/en not_active IP Right Cessation
- 1976-08-12 NL NL7608971A patent/NL7608971A/en not_active Application Discontinuation
- 1976-08-25 SE SE7609391A patent/SE439010B/en not_active IP Right Cessation
- 1976-08-27 CA CA259,993A patent/CA1062267A/en not_active Expired
- 1976-09-21 SU SU762399518A patent/SU604488A3/en active
- 1976-09-22 JP JP51113178A patent/JPS5239675A/en active Granted
- 1976-09-23 DD DD194962A patent/DD126907A1/xx unknown
- 1976-09-23 PL PL1976192594A patent/PL100503B1/en unknown
- 1976-09-24 CS CS766199A patent/CS196324B2/en unknown
- 1976-09-24 ES ES451829A patent/ES451829A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO762439L (en) | 1977-03-28 |
| CH601253A5 (en) | 1978-06-30 |
| RO69914A (en) | 1981-06-30 |
| NO145274C (en) | 1982-02-17 |
| CA1062267A (en) | 1979-09-11 |
| JPS5239675A (en) | 1977-03-28 |
| ATA735575A (en) | 1977-03-15 |
| SE439010B (en) | 1985-05-28 |
| ES451829A1 (en) | 1977-11-01 |
| FI63752B (en) | 1983-04-29 |
| FI63752C (en) | 1983-08-10 |
| PT65438B (en) | 1978-02-09 |
| DK144565B (en) | 1982-03-29 |
| JPS5333592B2 (en) | 1978-09-14 |
| PT65438A (en) | 1976-09-01 |
| NL7608971A (en) | 1977-03-29 |
| SU604488A3 (en) | 1978-04-25 |
| YU39360B (en) | 1984-10-31 |
| FI762025A (en) | 1977-03-26 |
| BG35040A3 (en) | 1984-01-16 |
| NO145274B (en) | 1981-11-09 |
| DK144565C (en) | 1982-09-13 |
| DD126907A1 (en) | 1977-08-17 |
| AT339897B (en) | 1977-11-10 |
| DK354376A (en) | 1977-03-26 |
| PL100503B1 (en) | 1978-10-31 |
| YU184876A (en) | 1982-06-30 |
| CS196324B2 (en) | 1980-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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