ES446093A1 - Procedure for the obtaining of derivatives of tetrahidropiridina. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Procedure for obtaining tetrahydropyridine derivatives of general formula I **(See formula)** wherein R1 signifies an aliphatic hydrocarbon residue with 1-12 or a cycloaliphatic hydrocarbon residue with -12 carbon atoms, the residues of which may be interrupted by oxygen, or a phenyl- (lower alkyl) residue, in which benzene ring at least three Hydrogen atoms may be substituted by substituents of the halogen compound group up to atomic number 35, lower alkyl and lower alkoxy groups, of the methylenedioxy group and of the trifluomethyl group or a cinnamyl moiety, if appropriate correspondingly substituted on the benzene ring, but which it cannot be a methyl group in the event that R2, R3, R4 and R5 each signify hydrogen, R2 signifies hydrogen or a lower alkyl group, R3 and R4, independent of each other signify hydrogen, lower alkyl or lower alkoxy groups, halogen atoms up to atomic number 35, or benzyl groups, and R3 can also mean a trifluoromethyl group, or lower alk-1-enyl, a 1-cycloalk-1-enyl group oo cycloalkyl, in each case with 5-8 carbon atoms, or R3 and R4 together trimethylene or tetramethylene moiety or, correspondingly a benzene ring condemning, the 1,3-butadienylene moiety, R5 means hydrogen or an alkyl group with maximum 4 atoms carbon, and its addition salts with inorganic and organic acids, characterized in that of a compound of general formula II **(See formula)** where R2, R3, R4 and R5 have the meaning indicated under formula I, water is cleaved and, if desired, a compound obtained of general formula I is transformed into an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)