ES446081A1 - Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora. - Google Patents
Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora.Info
- Publication number
- ES446081A1 ES446081A1 ES76446081A ES446081A ES446081A1 ES 446081 A1 ES446081 A1 ES 446081A1 ES 76446081 A ES76446081 A ES 76446081A ES 446081 A ES446081 A ES 446081A ES 446081 A1 ES446081 A1 ES 446081A1
- Authority
- ES
- Spain
- Prior art keywords
- inferior
- amino
- carbon atoms
- alquilo
- alcoxi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH244473A CH584209A5 (en) | 1973-02-20 | 1973-02-20 | 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity |
| FI193/74A FI60391C (fi) | 1973-02-20 | 1974-01-23 | Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES446081A1 true ES446081A1 (es) | 1977-06-16 |
Family
ID=25690464
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES76446081A Expired ES446081A1 (es) | 1973-02-20 | 1976-03-16 | Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora. |
| ES446083A Expired ES446083A1 (es) | 1973-02-20 | 1976-03-16 | Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES446083A Expired ES446083A1 (es) | 1973-02-20 | 1976-03-16 | Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora. |
Country Status (15)
| Country | Link |
|---|---|
| AR (6) | AR208397A1 (en, 2012) |
| AT (1) | AT335455B (en, 2012) |
| BE (1) | BE811274A (en, 2012) |
| CA (1) | CA1027131A (en, 2012) |
| CS (1) | CS203970B2 (en, 2012) |
| DD (1) | DD110041A5 (en, 2012) |
| DE (1) | DE2406930A1 (en, 2012) |
| DK (1) | DK143501C (en, 2012) |
| ES (2) | ES446081A1 (en, 2012) |
| FR (1) | FR2218101B1 (en, 2012) |
| GB (1) | GB1465946A (en, 2012) |
| IE (1) | IE38839B1 (en, 2012) |
| IL (1) | IL44202A (en, 2012) |
| LU (1) | LU69415A1 (en, 2012) |
| SE (1) | SE420834B (en, 2012) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4195090A (en) * | 1973-02-20 | 1980-03-25 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith |
| US4000282A (en) * | 1974-12-16 | 1976-12-28 | Merck & Co., Inc. | 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines |
| JPS5283759A (en) * | 1976-01-01 | 1977-07-12 | Merck & Co Inc | Substituted pyridines |
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
| US4091104A (en) * | 1976-06-15 | 1978-05-23 | Merck & Co., Inc. | Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use |
| US4092419A (en) * | 1976-06-15 | 1978-05-30 | Merck & Co., Inc. | Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use |
| DE2711655A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Pyridinyl-aminoalkylaether |
| US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
| US4753673A (en) * | 1977-07-22 | 1988-06-28 | The Dow Chemical Company | Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use |
| US4144343A (en) * | 1978-01-04 | 1979-03-13 | Merck & Co., Inc. | Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines |
| JPS54106476A (en) * | 1978-01-04 | 1979-08-21 | Merck & Co Inc | Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine |
| US4279913A (en) * | 1978-01-04 | 1981-07-21 | Merck & Co., Inc. | Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines |
| DK267779A (da) * | 1978-06-27 | 1979-12-28 | Merck & Co Inc | Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner |
| US4208416A (en) * | 1978-06-27 | 1980-06-17 | Merck & Co., Inc. | N-Aralkyl containing cyanopyridines |
| US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
| US4393212A (en) * | 1979-01-29 | 1983-07-12 | Merck & Co., Inc. | Certain nicotinic acid esters and corresponding nicotinonitriles |
| US4294969A (en) * | 1979-01-29 | 1981-10-13 | Merck & Co., Inc. | Process for producing 2-bromo-3,5-disubstituted pyridines |
| DD150456A5 (de) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols |
| US4281005A (en) | 1979-03-05 | 1981-07-28 | Merck & Co., Inc. | Novel 2-pyridylimidazole compounds |
| IT1165040B (it) * | 1979-04-23 | 1987-04-22 | Isf Spa | Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione |
| DE2943774A1 (de) * | 1979-10-26 | 1981-05-14 | 1000 Berlin Schering Ag Berlin Und Bergkamen | Substituierte pyridine, verfahren zu ihrer herstellung und ihre verwendung |
| IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
| FR2502618A1 (fr) * | 1981-03-25 | 1982-10-01 | Synthelabo | Derives de pyridine, leur preparation et leur application en therapeutique |
| US4517188A (en) * | 1983-05-09 | 1985-05-14 | Mead Johnson & Company | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols |
| US4598149A (en) * | 1984-03-02 | 1986-07-01 | Merck & Co., Inc. | 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| US7361671B2 (en) * | 2001-11-15 | 2008-04-22 | The Institute For Pharmaceutical Discovery, Inc. | Substituted heteroarylalkanoic acids |
| EA008148B1 (ru) | 2002-06-19 | 2007-04-27 | Биовитрум Аб | Новые соединения, их применение и получение |
| MXPA05005661A (es) * | 2002-11-27 | 2005-11-23 | Artesian Therapeutics Inc | Compuestos con actividad antagonista o antagonista parcial mixta inhibidora de fosfodiesterasa y beta-adrenergica para el tratamiento de insuficiencia cardiaca. |
| WO2006008191A1 (en) * | 2004-07-23 | 2006-01-26 | Bayer Cropscience Sa | 3-pyridinylethylbenzamide derivatives as fungicides |
| AU2010295288A1 (en) * | 2009-09-21 | 2012-05-03 | Johnson & Johnson | O-benzyl nicotinamide analogs as mGluR5 positive allosteric modulators |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1001631A (en) * | 1972-05-05 | 1976-12-14 | Merck Sharp And Dohme (I.A.) Corp. | 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation |
-
1974
- 1974-01-01 AR AR257054A patent/AR208397A1/es active
- 1974-01-01 AR AR257055A patent/AR207133A1/es active
- 1974-01-01 AR AR257058A patent/AR206801A1/es active
- 1974-01-29 SE SE7401114A patent/SE420834B/xx unknown
- 1974-02-11 IE IE255/74A patent/IE38839B1/xx unknown
- 1974-02-12 CA CA192,292A patent/CA1027131A/en not_active Expired
- 1974-02-13 GB GB651874A patent/GB1465946A/en not_active Expired
- 1974-02-13 IL IL44202A patent/IL44202A/xx unknown
- 1974-02-14 DE DE19742406930 patent/DE2406930A1/de not_active Ceased
- 1974-02-15 DK DK80774A patent/DK143501C/da not_active IP Right Cessation
- 1974-02-18 LU LU69415A patent/LU69415A1/xx unknown
- 1974-02-18 FR FR7405391A patent/FR2218101B1/fr not_active Expired
- 1974-02-18 DD DD176616A patent/DD110041A5/xx unknown
- 1974-02-19 AT AT133074A patent/AT335455B/de not_active IP Right Cessation
- 1974-02-19 BE BE141130A patent/BE811274A/xx not_active IP Right Cessation
- 1974-02-20 AR AR252438A patent/AR214612A1/es active
- 1974-02-20 CS CS741252A patent/CS203970B2/cs unknown
- 1974-12-23 AR AR257057A patent/AR203878A1/es active
-
1976
- 1976-01-01 AR AR264155A patent/AR208043A1/es active
- 1976-03-16 ES ES76446081A patent/ES446081A1/es not_active Expired
- 1976-03-16 ES ES446083A patent/ES446083A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE811274A (fr) | 1974-08-19 |
| DD110041A5 (en, 2012) | 1974-12-05 |
| IL44202A (en) | 1978-10-31 |
| AT335455B (de) | 1977-03-10 |
| CS203970B2 (en) | 1981-03-31 |
| LU69415A1 (en, 2012) | 1975-12-09 |
| DK143501C (da) | 1982-02-22 |
| FR2218101A1 (en, 2012) | 1974-09-13 |
| AR214612A1 (es) | 1979-07-13 |
| GB1465946A (en) | 1977-03-02 |
| DE2406930A1 (de) | 1974-08-22 |
| AR207133A1 (es) | 1976-09-15 |
| IE38839B1 (en) | 1978-06-07 |
| IE38839L (en) | 1974-08-20 |
| AR208043A1 (es) | 1976-11-22 |
| ES446083A1 (es) | 1977-09-16 |
| FR2218101B1 (en, 2012) | 1977-07-15 |
| ATA133074A (de) | 1976-07-15 |
| DK143501B (da) | 1981-08-31 |
| AR203878A1 (es) | 1975-10-31 |
| AR208397A1 (es) | 1976-12-27 |
| AR206801A1 (es) | 1976-08-23 |
| CA1027131A (en) | 1978-02-28 |
| SE420834B (sv) | 1981-11-02 |
| IL44202A0 (en) | 1974-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19840217 |