FR2218101B1 - - Google Patents

Info

Publication number
FR2218101B1
FR2218101B1 FR7405391A FR7405391A FR2218101B1 FR 2218101 B1 FR2218101 B1 FR 2218101B1 FR 7405391 A FR7405391 A FR 7405391A FR 7405391 A FR7405391 A FR 7405391A FR 2218101 B1 FR2218101 B1 FR 2218101B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7405391A
Other versions
FR2218101A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH244473A external-priority patent/CH584209A5/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2218101A1 publication Critical patent/FR2218101A1/fr
Application granted granted Critical
Publication of FR2218101B1 publication Critical patent/FR2218101B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7405391A 1973-02-20 1974-02-18 Expired FR2218101B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity
FI193/74A FI60391C (fi) 1973-02-20 1974-01-23 Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar

Publications (2)

Publication Number Publication Date
FR2218101A1 FR2218101A1 (fr) 1974-09-13
FR2218101B1 true FR2218101B1 (fr) 1977-07-15

Family

ID=25690464

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7405391A Expired FR2218101B1 (fr) 1973-02-20 1974-02-18

Country Status (15)

Country Link
AR (6) AR207133A1 (fr)
AT (1) AT335455B (fr)
BE (1) BE811274A (fr)
CA (1) CA1027131A (fr)
CS (1) CS203970B2 (fr)
DD (1) DD110041A5 (fr)
DE (1) DE2406930A1 (fr)
DK (1) DK143501C (fr)
ES (2) ES446081A1 (fr)
FR (1) FR2218101B1 (fr)
GB (1) GB1465946A (fr)
IE (1) IE38839B1 (fr)
IL (1) IL44202A (fr)
LU (1) LU69415A1 (fr)
SE (1) SE420834B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195090A (en) * 1973-02-20 1980-03-25 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
US4000282A (en) * 1974-12-16 1976-12-28 Merck & Co., Inc. 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines
JPS5283759A (en) * 1976-01-01 1977-07-12 Merck & Co Inc Substituted pyridines
US4091104A (en) * 1976-06-15 1978-05-23 Merck & Co., Inc. Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use
US4092419A (en) * 1976-06-15 1978-05-30 Merck & Co., Inc. Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use
US4060601A (en) * 1976-06-15 1977-11-29 Merck & Co., Inc. Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines
DE2711655A1 (de) * 1977-03-17 1978-09-21 Basf Ag Pyridinyl-aminoalkylaether
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4753673A (en) * 1977-07-22 1988-06-28 The Dow Chemical Company Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines
JPS54106476A (en) * 1978-01-04 1979-08-21 Merck & Co Inc Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine
US4279913A (en) * 1978-01-04 1981-07-21 Merck & Co., Inc. Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
DK267779A (da) * 1978-06-27 1979-12-28 Merck & Co Inc Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner
US4393212A (en) * 1979-01-29 1983-07-12 Merck & Co., Inc. Certain nicotinic acid esters and corresponding nicotinonitriles
US4294969A (en) * 1979-01-29 1981-10-13 Merck & Co., Inc. Process for producing 2-bromo-3,5-disubstituted pyridines
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
US4281005A (en) 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
IT1165040B (it) * 1979-04-23 1987-04-22 Isf Spa Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione
DE2943774A1 (de) * 1979-10-26 1981-05-14 1000 Berlin Schering Ag Berlin Und Bergkamen Substituierte pyridine, verfahren zu ihrer herstellung und ihre verwendung
IL62602A (en) * 1980-05-19 1984-06-29 Labaz Sanofi Nv Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
FR2502618A1 (fr) * 1981-03-25 1982-10-01 Synthelabo Derives de pyridine, leur preparation et leur application en therapeutique
US4517188A (en) * 1983-05-09 1985-05-14 Mead Johnson & Company 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
US7361671B2 (en) * 2001-11-15 2008-04-22 The Institute For Pharmaceutical Discovery, Inc. Substituted heteroarylalkanoic acids
BR0311970A (pt) 2002-06-19 2005-03-29 Biovitrum Ab Novos compostos, seu uso e preparação
JP2006509790A (ja) * 2002-11-27 2006-03-23 アルテシアン セラピューティック,インコーポレイティド 心不全の治療のための混合されたPDE阻害およびβアドレナリン拮抗薬活性または部分的作用薬活性を有する化合物
US20080033020A1 (en) * 2004-07-23 2008-02-07 Darren Mansfield 3-Pyridinylethylbenzamide Derivatives as Fungicides
BR112012006330A2 (pt) * 2009-09-21 2017-07-04 Janssen Cilag S A análogos de o-benzil nicotinamida como moduladores alostéricos positivos de mglur5

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1001631A (en) * 1972-05-05 1976-12-14 Merck Sharp And Dohme (I.A.) Corp. 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation

Also Published As

Publication number Publication date
AR203878A1 (es) 1975-10-31
ATA133074A (de) 1976-07-15
AR206801A1 (es) 1976-08-23
IE38839L (en) 1974-08-20
AR208043A1 (es) 1976-11-22
DE2406930A1 (de) 1974-08-22
ES446083A1 (es) 1977-09-16
IE38839B1 (en) 1978-06-07
CS203970B2 (en) 1981-03-31
DD110041A5 (fr) 1974-12-05
AT335455B (de) 1977-03-10
ES446081A1 (es) 1977-06-16
CA1027131A (fr) 1978-02-28
AR208397A1 (es) 1976-12-27
FR2218101A1 (fr) 1974-09-13
AR214612A1 (es) 1979-07-13
DK143501B (da) 1981-08-31
LU69415A1 (fr) 1975-12-09
AR207133A1 (es) 1976-09-15
IL44202A0 (en) 1974-06-30
GB1465946A (en) 1977-03-02
BE811274A (fr) 1974-08-19
IL44202A (en) 1978-10-31
DK143501C (da) 1982-02-22
SE420834B (sv) 1981-11-02

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Legal Events

Date Code Title Description
ST Notification of lapse