ES443476A1 - Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing them - Google Patents
Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing themInfo
- Publication number
- ES443476A1 ES443476A1 ES443476A ES443476A ES443476A1 ES 443476 A1 ES443476 A1 ES 443476A1 ES 443476 A ES443476 A ES 443476A ES 443476 A ES443476 A ES 443476A ES 443476 A1 ES443476 A1 ES 443476A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- tetrazolyl
- alkyl
- carboxyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D335/16—Oxygen atoms, e.g. thioxanthones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Thioxanthone derivatives of the formula I, wherein Z<1> denotes a carboxyl, 5-tetrazolyl, 5-(1-alkyl)tetrazolyl or 5-(2-alkyl)tetrazolyl group, with the alkyl groups having 1 to 6 carbon atoms and being optionally substituted by a hydroxyl group or a basic or acidic group and Z<2> denotes hydrogen, halogen, an amino or nitro group, an alkyl group having 1 to 6 carbon atoms, an alkoxy, alkylthio, acyl or acylamino group having 1 to 6 carbon atoms or a 5-tetrazolyl, 5-(1-alkyl)tetrazolyl or 5-(2-alkyl)tetrazolyl group, with the alkyl groups having 1 to 6 carbon atoms and being optionally substituted by a hydroxyl group or a basic or acidic group, are active compounds and are obtained if appropriately substituted diphenyl sulphide derivatives, which in the 2-position possess a carboxyl group or a reactive functional derivative of such a group, are cyclised in the presence of Lewis acids or of protonic acids. The compounds are optionally converted to their salts or, if at least one of the substituents is a carboxyl group, to their esters or amides by esterification or amidation. The compounds act as inhibitors of certain allergic reactions in mammals. Several of the compounds of the formula I which have been prepared are novel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4143372A GB1458185A (en) | 1972-09-06 | 1972-09-06 | Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing them |
| GB3341073 | 1973-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES443476A1 true ES443476A1 (en) | 1977-08-16 |
Family
ID=26261859
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES418514A Expired ES418514A1 (en) | 1972-09-06 | 1973-09-05 | Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing them |
| ES443476A Expired ES443476A1 (en) | 1972-09-06 | 1975-12-13 | Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing them |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES418514A Expired ES418514A1 (en) | 1972-09-06 | 1973-09-05 | Carboxyl and tetrazolyl cerivatives of thioxanthones methods for their preparation and compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5829309B2 (en) |
| CA (1) | CA1023365A (en) |
| CH (1) | CH614203A5 (en) |
| DE (1) | DE2344799A1 (en) |
| ES (2) | ES418514A1 (en) |
| FR (2) | FR2197607B1 (en) |
| GB (1) | GB1458185A (en) |
| IE (1) | IE38329B1 (en) |
| IL (1) | IL43162A0 (en) |
| NL (1) | NL7312253A (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55122785A (en) * | 1979-03-15 | 1980-09-20 | Yoshitomi Pharmaceut Ind Ltd | Preparation of benzopyranopyridine derivative |
| CH640849A5 (en) * | 1979-05-18 | 1984-01-31 | Ciba Geigy Ag | THIOXANTHONICARBONIC ACID ESTERS, THIOESTERS AND AMIDES. |
| US4367324A (en) | 1980-02-05 | 1983-01-04 | Ciba-Geigy Corporation | Photocrosslinkable polymers with thioxanthone and imidyl groupings in side chains |
| US4348530A (en) * | 1980-02-05 | 1982-09-07 | Ciba-Geigy Corporation | Thioxanthonecarboxylic acids, esters, thioesters and amides with reactive functional groups |
| CH643552A5 (en) * | 1980-05-06 | 1984-06-15 | Ciba Geigy Ag | THIOXANTHONIC CARBON ACIDS AND THIOXANTHON CARBON ACID DERIVATIVES. |
| US4564578A (en) * | 1982-11-25 | 1986-01-14 | Ciba-Geigy Corporation | Novel thioxanthones substituted by alpha-aminoalkyl groups |
| EP0150891A1 (en) * | 1984-01-05 | 1985-08-07 | The Wellcome Foundation Limited | Tricyclic compounds, processes for their preparation, compositions containing such compounds and their use in medicine |
| GB8400201D0 (en) | 1984-01-05 | 1984-02-08 | Wellcome Found | Tricyclic compounds |
| GB8400203D0 (en) * | 1984-01-05 | 1984-02-08 | Wellcome Found | Tricyclic compounds |
| CN101906095B (en) * | 2010-07-06 | 2013-08-14 | 天津久日化学股份有限公司 | Thioxathone-4-carboxylic ester and preparation method as well as photoinitiator composition and application |
| JP7372904B2 (en) * | 2018-02-16 | 2023-11-01 | 株式会社Adeka | Radical polymerization initiator, composition containing same, cured product thereof, manufacturing method thereof, and compound |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793954A (en) * | 1972-07-19 | 1973-07-12 | Syntex Corp | THIOXANTHONE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES |
-
1972
- 1972-09-06 GB GB4143372A patent/GB1458185A/en not_active Expired
-
1973
- 1973-09-05 ES ES418514A patent/ES418514A1/en not_active Expired
- 1973-09-05 DE DE19732344799 patent/DE2344799A1/en not_active Ceased
- 1973-09-05 IL IL43162A patent/IL43162A0/en unknown
- 1973-09-06 NL NL7312253A patent/NL7312253A/xx not_active Application Discontinuation
- 1973-09-06 CH CH1282773A patent/CH614203A5/en not_active IP Right Cessation
- 1973-09-06 CA CA180,382A patent/CA1023365A/en not_active Expired
- 1973-09-06 IE IE1590/73A patent/IE38329B1/en unknown
- 1973-09-06 JP JP48100727A patent/JPS5829309B2/en not_active Expired
- 1973-09-06 FR FR7332118A patent/FR2197607B1/fr not_active Expired
-
1975
- 1975-12-13 ES ES443476A patent/ES443476A1/en not_active Expired
-
1976
- 1976-01-14 FR FR7600805A patent/FR2289184A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CA1023365A (en) | 1977-12-27 |
| DE2344799A1 (en) | 1974-03-21 |
| FR2197607B1 (en) | 1977-01-28 |
| IE38329B1 (en) | 1978-02-15 |
| JPS5829309B2 (en) | 1983-06-22 |
| IL43162A0 (en) | 1973-11-28 |
| AU6003573A (en) | 1975-03-06 |
| GB1458185A (en) | 1976-12-08 |
| ES418514A1 (en) | 1977-01-01 |
| FR2289184B1 (en) | 1979-09-28 |
| NL7312253A (en) | 1974-03-08 |
| FR2197607A1 (en) | 1974-03-29 |
| JPS4992072A (en) | 1974-09-03 |
| FR2289184A1 (en) | 1976-05-28 |
| IE38329L (en) | 1974-03-06 |
| CH614203A5 (en) | 1979-11-15 |
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